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Genoprotective Effect of Melatonin Against to the Genotoxicity of Glyphosate on Human Blood Lymphocytes

Kim JG, Choi WI, Lee JH, Choi IJ, Jin SC

PURPOSE: Glyphosate is a widely used non-selective herbicide. Previous studies have shown that glyphosate has genotoxicity, and that even low-doses of glyphosate can cause DNA damage. Melatonin is a hormone...
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In vitro Effects of Epigallocatechin Gallate on Sister Chromatid Exchange in the Lymphocytes Exposed to Glyphosate

Park JM, Choi WI, Jin SC, Lee JH, Choi IJ

PURPOSE: Green tea is known as a potent anti-oxidant, anti-carcinogen, and genetic protector. Glyphosate (N-phosphonomethyl glycine) is a widely used non-selective herbicide that causes DNA damage. The present study was...
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Genotoxicity of low-dose Glyphosate by Sister Chromatid Exchange

Lee SH, Kim SJ, Choi WI, Jin SC, Choi IJ, Lee JH

  • KMID: 2025759
  • J Korean Soc Clin Toxicol.
  • 2014 Jun;12(1):8-13.
PURPOSE: Glyphosate (N-phosphonomethyl glycine) is widely used as an herbicide for weed control in rural areas. It is also readily available for suicide attempts. Glyphosate has high toxicity and negatively...
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Cytogenetic Finding of Breast Cancer Cases and in Their First-Degree Relatives

Celik DA, Kosar PA, Ozcelik N, Eroglu E

PURPOSE: The aim of this study was to evaluate and compare the rate of sister chromatid exchange (SCE), the occurrence of micronuclei, and the lymphocyte proliferation rate index (PRI) in...
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Health Effects of Chemicals used in hospitals among Healthcare Workers

Won JU

Healthcare workers are exposed to a variety of chemical agents used in many different areas and purposes. The chemicals could cause health problems to healthcare workers using them. Glutaraldehyde is...
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The Effects of Etodolac, Nimesulid and Naproxen Sodium on the Frequency of Sister Chromatid Exchange after Enclused Third Molars Surgery

Koseoglu B, Ozturk S, Kocak H, Palanduz S, Cefle K

PURPOSE: Non-steroidal anti-inflammatory drugs (NSAID) are frequently used in oral surgical procedures in dentistry. The evaluation of the frequency of sister chromatid exchange (SCE) is accepted as a reliable cytogenetic...
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Effects of Smoking and Age on SCE Frequency Reflecting DNA Damage of Human Lymphocytes in Elderly Koreans

Lee JH, Kang MH

  • KMID: 1618398
  • Korean J Nutr.
  • 2003 Oct;36(8):851-858.
Sister chromatid exchange (SCE) has recently become a common cytogenic assay system for detecting exposure to chemical mutagens and carcinogens. One application of SCE is the monitoring of populations believed...
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Effects of Stem Cell and Myeloperoxidase on Sister Chromatid Exchanges and Micronuclei Induction of Peripheral Lymphocytes by Styrene, Hydroquinone and Trichloroethylene

Lee KJ, Kim HA, Shin MJ, Sung JH, Park CY, Han H, Lee SH

  • KMID: 2028158
  • Korean J Occup Environ Med.
  • 2001 Sep;13(3):315-324.
OBJECTIVES: The objective of this study was to identify the possible role of stem cell and myeloperoxidase (MPO) in the metabolic activation of styrene, hydroquinone and trichloroethylene, by investigating the...
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Concentration of Urinary Cotinine and Frequency of Sister Chromatid Exchange in Lymphocytes among Male Adolescents

Paek DK, Chang SS, Lee TY, Roh YM, Lee Y, Cho YC, Lee DB

  • KMID: 1876276
  • Korean J Prev Med.
  • 2001 Aug;34(3):269-276.
OBJECTIVES: To evaluate the internal burden and hazardous effects associated with smoking in middle and high school students. METHODS: We analysed urinary cotinine (U-cotinine) concentrations and the frequency of Sister Chromatid...
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Detection of hepatitis B virus DNA and sister chromatid exchange in peripheral bloods from patients with chronic hepatitis B

Choi WI, Kim DK

  • KMID: 2092697
  • Korean J Anat.
  • 1999 Oct;32(5):629-635.
In the present study author investigated 48 patients with chronic hepatitis B for the presence of peripheral blood HBV-DNA with the aid of DNA molecular techniques. HBV-DNA was detected in...
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Sister Chromatid Exchange Frequencies in Stomach Cancer Patients

Park CS, Kim DK

  • KMID: 2092695
  • Korean J Anat.
  • 1999 Oct;32(5):615-617.
This study was made to show the effect of stomach cancer on chromosome by sister chromatid exchange (SCE) analysis, because very few studies have reported. Metaphase preparation from peripheral blood...
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Chromosome Aberrations and Sister-chromatid Exchanges in Workers Exposed to Mixed-organic Solvents in Shoe-making Workshops

Song J, Lee SJ, Roh SC, Sohn SJ, Oh HY, Park CH, Han ES, Ha KW

  • KMID: 1546031
  • Korean J Aerosp Environ Med.
  • 1999 Jun;9(2):207-214.
Chromosome aberrations and sister chromatid exchanges (SCEs) in lymphocytes of peropheral blood as an indicator which could evaluate the effects of mutagenicity after in human exposure to mixed-organic solvents were...
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Sister Chromatid Exchanges in Workers Occupationally Exposed to Ethylene Oxide

Chang SH, Lee WJ, Kim CS, Hwang CH, Park JT, Kim DS, Kim YW

  • KMID: 2028035
  • Korean J Occup Environ Med.
  • 1998 Dec;10(4):428-437.
Operators of hospital sterilizers who use ethylene oxide (EtO) were studied to determine the exposure of EtO level and the frequency of sister chromatid exchanges (SCEs) from June 12 to...
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Chromosome Aberrations and Sister Chromatid Exchanges of Hospital Workers Exposed to Radiation

Cha AR, Kim MS, Hwang IK, Lee SI, Cho BM, Kim DK

  • KMID: 2282955
  • Korean J Prev Med.
  • 1998 Nov;31(4):616-627.
In order to evaluate the cytogenetic hazard among hospital workers potentially exposed to low dose of radiation, the analysis of chromosome aberrations(CA) and sister chromatid exchanges(SCE) in lymphocytes were performed...
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Assessment of Genotoxic Hazard in Petrochemical Workers

Moon JD, Suh SP, Park JS, Cho JH, Ahn KW

  • KMID: 2028002
  • Korean J Occup Environ Med.
  • 1998 Feb;10(1):53-60.
In order to evaluate the genotoxic hazard among workers potentially exposed to low level petrochemical substances, the analyses of micronuclei (MN) and sister chromatid exchanges (SCEs) in lymphocytes were performed...
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Chromosomal Vulnerability to gamma-irradiation of Peripheral Blood Lymphocytes in Patients with Various Cancers

Cho D, Bom HS, Choi KH, Byun DE, Kim SH, Sun SP

  • KMID: 2089456
  • Korean J Clin Pathol.
  • 1997 Aug;17(4):662-667.
BACKGROUND: Human cancel can be induced by various environmental factors such as virus, chemicals, and radiations. However, susceptibility of host to these environmental factors is not well studied. The purpose...
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The Study of Chromosomal Aberration in NSCLC Patients which Developed after Administration of Chemotherapeutic Agents

Cha WK, Lee JY, Shinn JJ, Lee HK, Yu KH, Song JS, Yang KH, Kim ES, Kim JS

  • KMID: 1906182
  • J Korean Cancer Assoc.
  • 1997 Jun;29(3):504-511.
PURPOSE: Except hormonal agents and biologic response modifier, the biologic effects of chemotherapy and radiotherapy as anti-cancer therapy have the mechanism of DNA injury. They cause not only cancer cell...
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The effects of chromium exposure on sister chromatid exchange and concentration of 8-hydroxydeoxyguanosine

Han SH, Cho SH, Kim H, Park SM, Ha M, Joo YS, Kwon HJ, Kwon YD, Kwon MH

  • KMID: 2282757
  • Korean J Prev Med.
  • 1995 Jun;28(2):511-525.
To elucidate some DNA adducts as a biological marker for workers of chromate pigment, the effects of chromium exposure on the formation of 8-hydroxydeoxyguanosine(8-OH-dG) and sister chromatid exchanges(SCEs) frequency in...
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A study on the Frequency of Sister Chromatid Exchanges in Peripheral Lymphocytes among Painters

Yang SR

  • KMID: 2074950
  • Korean J Occup Environ Med.
  • 1994 Sep;6(2):332-341.
The author studied the frequencies of sister chromatid exchanges of cultured peripheral Iymphocytes from 51 chromium exposed workers and 29 controls in order to examine the inductivity of sister chromatid...
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Development of Methods to Estimate Exposure Levels to Vinyl Chloride Monomer and Multiphasic Screening Tests for Workers of Polyvinyl Chloride Manufacturing Factories

Kim H, Nam YJ, Kim ST, Kim DY, Han SH, Park KT

  • KMID: 2074939
  • Korean J Occup Environ Med.
  • 1994 Sep;6(2):201-218.
In order to develop questionnaire estimating vinyl chloride monomer(VCM) exposure levels, to reset selection criteria for detailed tests, to measure current VCM exposure levels, to evaluate the mutagenic effects of...
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