- Features and Outcomes of Children with Ulcerative Colitis who Undergo a Diagnostic Change: A Single-Center Experience
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Ito N, Takeuchi I, Kyodo R, Hirano Y, Sato T, Usami M, Shimizu H, Shimizu T, Arai K
- KMID: 2518435
- Pediatr Gastroenterol Hepatol Nutr.
- 2021 Jul;24(4):357-365.
- doi: 10.5223/pghn.2021.24.4.357
Purpose: A change in diagnosis from ulcerative colitis (UC) to Crohn's disease (CD) has been reported in pediatric inflammatory bowel disease; however, only a few clinical characteristics and predictors of... -
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- Long-Term Efficacy and Safety of Golimumab for Ulcerative Colitis in a Pediatric Inflammatory Bowel Disease Center in Japan
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Tokita K, Shimizu H, Takeuchi I, Shimizu T, Arai K
- KMID: 2535163
- Pediatr Gastroenterol Hepatol Nutr.
- 2022 Nov;25(6):461-472.
- doi: 10.5223/pghn.2022.25.6.461
Purpose: Golimumab (GLM) is an anti-tumor necrosis factor (TNF)-α antibody preparation known to be less immunogenic than infliximab (IFX) or adalimumab. Few reports on GLM in pediatric patients with ulcerative... -
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- Predictors of Small Bowel Transit Time for Capsule Endoscopy in Children with Inflammatory Bowel Disease
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Oka I, Funayama R, Shimizu H, Takeuchi I, Nojiri S, Shimizu T, Arai K
- KMID: 2544881
- Pediatr Gastroenterol Hepatol Nutr.
- 2023 Jul;26(4):181-192.
- doi: 10.5223/pghn.2023.26.4.181
Purpose: The development of assistive devices has allowed for the performance of capsule endoscopy in children. Anticipating the capsule’s transit time could affect the efficacy of the investigation and potentially... -
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- Long-Term Durability of Infliximab for Pediatric Ulcerative Colitis: A Retrospective Data Review in a Tertiary Children's Hospital in Japan
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Shimizu H, Arai K, Takeuchi I, Minowa K, Hosoi K, Sato M, Oka I, Kaburaki Y, Shimizu T
- KMID: 2510620
- Pediatr Gastroenterol Hepatol Nutr.
- 2021 Jan;24(1):7-18.
- doi: 10.5223/pghn.2021.24.1.7
Purpose: The long-term efficacy and safety of infliximab (IFX) in children with ulcerative colitis (UC) have not been well-evaluated. Here, we reviewed the long-term durability and safety of IFX in... -
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- Ramelteon for Delayed Sleep-wake Phase Disorder: A Case Report
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Takeshima M, Shimizu T, Ishikawa H, Kanbayashi T
- KMID: 2502140
- Clin Psychopharmacol Neurosci.
- 2020 Feb;18(1):167-169.
- doi: 10.9758/cpn.2020.18.1.167
Recently developed melatonin receptor agonists are expected to be effective for delayed sleep-wake phase disorder (DSWPD). To date, however, no study has described the effect of melatonin receptor agonists on... -
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- Relationship between Clozapine-Induced Electroencephalogram Abnormalities and Serum Concentration of Clozapine in Japanese Patients with Treatment-Resistant Schizophrenia
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Kikuchi YS, Kanbayashi T, Shimizu T
- KMID: 2447785
- Psychiatry Investig.
- 2019 Apr;16(4):279-284.
- doi: 10.30773/pi.2018.12.16
OBJECTIVE: The objective of this study was to investigate the relationship between the serum concentration of clozapine (C-CLZ), N-desmethylclozapine (N-CLZ) and the daily dose of CLZ (D-CLZ), and the relationships... -
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- Physical Activity and Activities of Daily Living in Older Adult Patients With Heart Failure Admitted for Subacute Musculoskeletal Disease
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Shimizu T, Kanai C, Ueda K, Asakawa Y
- KMID: 2548401
- Ann Rehabil Med.
- 2023 Oct;47(5):426-437.
- doi: 10.5535/arm.23031
Objective: To examine activities of daily living (ADL) and physical activity in older adults with heart failure admitted to a rehabilitation ward for subacute musculoskeletal disease. Methods: This study included patients... -
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- Successful Management of Clozapine-induced Akathisia with Gabapentin Enacarbil: A Case Report
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Takeshima , Ishikawa H, Kikuchi Y, Kanbayashi T, Shimizu T
- KMID: 2419991
- Clin Psychopharmacol Neurosci.
- 2018 Aug;16(3):346-348.
- doi: 10.9758/cpn.2018.16.3.346
The management of clozapine (CLZ)-induced adverse events affects patient prognoses. Akathisia is a relatively rare adverse event related to CLZ administration and thus the management of this syndrome is not... -
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- Phenotypic characteristics of pediatric inflammatory bowel disease in Japan: results from a multicenter registry
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Arai K, Kunisaki R, Kakuta F, Hagiwara Si, Murakoshi T, Yanagi T, Shimizu T, Kato S, Ishige T, Aomatsu T, Inoue M, Saito T, Iwama I, Kawashima H, Kumagai H, Tajiri H, Iwata N, Mochizuki T, Noguchi A, Kashiwabara T, Shimizu H, Suzuki Y, Hirano Y, Fujiwara T
- KMID: 2508568
- Intest Res.
- 2020 Oct;18(4):412-420.
- doi: 10.5217/ir.2019.00130
Background/Aims: There are few published registry studies from Asia on pediatric inflammatory bowel disease (IBD). Registry network data enable comparisons among ethnic groups. This study examined the characteristics of IBD... -
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- Repair of Iliac Crest Defects with a Hydroxyapatite/Collagen Composite
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Murata K, Fujibayashi S, Otsuki B, Shimizu T, Matsuda S
- KMID: 2510557
- Asian Spine J.
- 2020 Dec;14(6):808-813.
- doi: 10.31616/asj.2019.0310
Study Design: Retrospective study. Purpose: This study aimed to assess the effect of refilling with hydroxyapatite/collagen (HAp/Col) composite on an iliac crest defect after spinal fusion. Overview of Literature: The use of... -
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- Efficacy and Safety of Abdominal Trunk Muscle Strengthening Using an Innovative Device in Elderly Patients With Chronic Low Back Pain: A Pilot Study
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Kato S, Demura S, Kurokawa Y, Takahashi N, Shinmura K, Yokogawa N, Yonezawa N, Shimizu T, Kitagawa R, Tsuchiya H
- KMID: 2504445
- Ann Rehabil Med.
- 2020 Jun;44(3):246-255.
- doi: 10.5535/arm.19100
Objective To examine the efficacy and safety of an innovative, device-driven abdominal trunk muscle strengthening program, with the ability to measure muscle strength, to treat chronic low back pain... -
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- Sagittal Section Hounsfield Units of the Upper Instrumented Vertebrae as a Predictor of Proximal Junctional Vertebral Fractures Following Adult Spinal Deformity Surgery
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Murata K, Otsuki B, Shimizu T, Sono T, Fujibayashi S, Matsuda S
- KMID: 2554736
- Asian Spine J.
- 2024 Apr;18(2):209-217.
- doi: 10.31616/asj.2023.0339
Study Design: A retrospective observational study. Purpose: This study aimed to determine an accurate and convenient screening method for predicting proximal junctional fractures (PJFr) following surgery for adult spinal deformity (ASD)... -
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- Predictive Value of Heterogeneously Enhanced Magnetic Resonance Imaging Findings With Computed Tomography Evidence of Calcification for Severe Motor Deficits in Spinal Meningioma
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Ono K, Shimizu T, Fujibayashi S, Otsuki B, Murata K, Sakamoto A, Matsuda S
- KMID: 2514299
- Neurospine.
- 2021 Mar;18(1):163-169.
- doi: 10.14245/ns.2040494.247
Objective: Spinal meningioma is mostly benign, but they can exhibit neurological deficit. The relationship between neurological impairment and its radiographic findings, including intratumor magnetic resonance imaging (MRI) gadolinium enhancement and... -
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- Safety and Recipient Satisfaction of Propofol Sedation in Outpatient Endoscopy: A 24-Hour Prospective Investigation Using a Questionnaire Survey
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Kanno Y, Ohira T, Harada Y, Koshita S, Ogawa T, Kusunose H, Koike Y, Yamagata T, Sakai T, Masu K, Yonamine K, Miyamoto K, Tanaka M, Shimada T, Kozakai F, Endo K, Okano H, Komabayashi D, Shimizu T, Suzuki S, Ito K
- KMID: 2516313
- Clin Endosc.
- 2021 May;54(3):340-347.
- doi: 10.5946/ce.2020.138
Background/Aims: The aim of this study was to evaluate the safety of sedation with propofol as an alternative to benzodiazepine drugs in outpatient endoscopy. Methods: In this prospective study, examinees who... -
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- Temperature-Responsive surface for novel co-culture systems of hepatocytes with endothelial cells: 2-D patterned and double layered co-cultures
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Hirose M, Yamato M, Kwon OH, Harimoto M, Kushida A, Shimizu T, Kikuchi A, Okano T
- KMID: 1114568
- Yonsei Med J.
- 2000 Dec;41(6):803-813.
- doi: 10.3349/ymj.2000.41.6.803
We have developed two novel cell co-culture system, without any on cell type combination limitation, utilizing a polymer surface which is temperature-sensitive with respect to its cell adhesion characteristics. One... -
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- Effects of Stress on Mouse beta-Defensin-3 Expression in the Upper Digestive Mucosa
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Kawashima , Shimizu T, To M, Saruta J, Jinbu Y, Kusama M, Tsukinoki
- KMID: 2386467
- Yonsei Med J.
- 2014 Mar;55(2):387-394.
PURPOSE: Gastrointestinal integrity and immune surveillance are affected by stress. Stress also adversely affects mucosal barrier function. beta-defensins constitute an integral component of the innate immune system as antimicrobial peptides,... -
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- Multicenter Prospective Study of Lateral Lumbar Interbody Fusions Using Bioactive Porous Titanium Spacers without Bone Grafts
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Fujibayashi S, Takemoto M, Ishii K, Funao H, Isogai N, Otsuki B, Shimizu T, Nakamura T, Matsuda S
- KMID: 2537260
- Asian Spine J.
- 2022 Dec;16(6):890-897.
- doi: 10.31616/asj.2021.0354
Study Design: Prospective multicenter clinical study. Purpose: To evaluate the efficacy of bioactive surface treatment for porous titanium spacers without bone graft for lateral lumbar interbody fusion (LLIF) through clinical and... -
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- Significance of intraprostatic architecture and regrowth velocity for considering discontinuation of dutasteride after combination therapy with an alpha blocker: A prospective, pilot study
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Shindo T, Hashimoto , Shimizu T, Itoh N, Masumori N
- KMID: 2155306
- Korean J Urol.
- 2015 Apr;56(4):305-309.
- doi: 10.4111/kju.2015.56.4.305
PURPOSE: We conducted a prospective single-center study to evaluate the possibility of discontinuation of dutasteride after combination therapy with an alpha blocker for benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: We... -
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- The Relationship between the Occipitocervical Junction and Thoracic Kyphosis in Ankylosing Spondylitis: A Retrospective Cohort Study of 86 Cervical Fractures in Surgically Treated Patients
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Manabe N, Covaro A, Bobinski L, Shimizu T, Olerud C, Robinson Y
- KMID: 2441544
- Asian Spine J.
- 2019 Feb;13(1):103-110.
- doi: 10.31616/asj.2018.0010
STUDY DESIGN: Retrospective analysis of prospectively collected data. PURPOSE: To describe the radiological characteristics of the occipitocervical area in patients with ankylosing spondylitis (AS) using the novel measure X-angle and to... -
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- Implantation of Bone Marrow Stromal Cell Sheets Derived from Old Donors Supports Bone Tissue Formation
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Akahane M, Shimizu T, Inagaki Y, Kira T, Egawa T, Okuda A, Onishi T, Imamura T, Tanaka Y
- KMID: 2405970
- Tissue Eng Regen Med.
- 2018 Feb;15(1):89-100.
- doi: 10.1007/s13770-017-0088-4
The purpose of this study was to evaluate the osteogenesis ability of osteogenic matrix cell sheets (OMCS) derived from old donor cells. Bone marrow stromal cells (BMSC) were obtained from... -
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