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Modulatory Potential of LncRNA Zfas1 for Inflammation and Neuronal Apoptosis in Temporal Lobe Epilepsy

He C, Su C, Zhang W, Zhou Q, Shen X, Yang J, Shi N

Purpose: This study aimed to elucidate whether lncRNA ZFAS1 is involved in neuronal apoptosis and inflammation in temporal lobe epilepsy (TLE). Materials and Methods: Ninety-six TLE patients were recruited, and their...
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Intra-Articular Injection of miR-29a-3p of BMSCs Promotes Cartilage Self-Repairing and Alleviates Pain in the Rat Osteoarthritis

Wang Q, Chen Y, Shen X, Chen J, Li Y

BACKGROUND: Stem cells intra-articular injection stagey indicated a potential therapeutic effect on improving the pathological progress of osteoarthritis (OA). However, the long-term effect of stem cells intra-articular injection on the...
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Perceptions of a night float system for intern doctors in an internal medicine program: an Asian perspective

Tan BY, Ngiam NJ, Chang ZY, Tan SM, Shen X, Mok SF, Subramanian S, Ooi SB, Kee AC

Long duty hours have been associated with significant medical errors, adverse events, and physician “burn-out”. An innovative night float (NF) system has been implemented in our internal medicine program to...
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Benefits of procyanidins on gut microbiota in Bama minipigs and implications in replacing antibiotics

Zhao T, Shen X, Dai C, Cui L

Several studies have reported the effect of absorption of procyanidins and their contribution to the small intestine. However, differences between dietary interventions of procyanidins and interventions via antibiotic feeding in...
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One-Carbon Metabolism Nutrients, Genetic Variation, and Diabetes Mellitus

Zhu J, Saikia G, Zhang X, Shen X, Kahe K

Diabetes mellitus (DM) affects about 9.3% of the population globally. Hyperhomocysteinemia (HHcy) has been implicated in the pathogenesis of DM, owing to its promotion of oxidative stress, β-cell dysfunction, and...
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Mutational analysis of KRAS and its clinical implications in cervical cancer patients

Jiang W, Xiang L, Pei X, He T, Shen X, Wu X, Yang H

OBJECTIVE: The predictive and prognostic role of KRAS mutations in cervical cancer remains inconclusive. The aim of this study was to explore the clinicopathological and prognostic relevance of KRAS mutations...
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Spatial analysis of tuberculosis treatment outcomes in Shanghai: implications for tuberculosis control

Zhang J, Shen X, Yang C, Chen Y, Guo J, Wang D, Zhang J, Lynn H, Hu Y, Pan Q, Zhang Z

OBJECTIVES: Tuberculosis (TB) treatment outcomes are a key indicator in the assessment of TB control programs. We aimed to identify spatial factors associated with TB treatment outcomes, and to provide...
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Distal pancreatectomy with splenectomy for the management of splenic hilum metastasis in cytoreductive surgery of epithelial ovarian cancer

Xiang L, Tu Y, He T, Shen X, Li Z, Wu X, Yang H

OBJECTIVE: Distal pancreatectomy with splenectomy may be required for optimal cytoreductive surgery in patients with epithelial ovarian cancer (EOC) metastasized to splenic hilum. This study evaluates the morbidity and treatment...
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Anti-diabetic activities of catalpol in db/db mice

Bao Q, Shen X, Qian L, Gong C, Nie M, Dong Y

The objective was to investigate the hypoglycemic action of catalpol in spontaneous diabetes db/db mice. 40 db/db mice were randomly divided into fi ve groups: model control gourp; db/db plus...
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Macrophage migration inhibitory factor mediates peripheral nerve injury-induced hypersensitivity by curbing dopaminergic descending inhibition

Wang X, Ma S, Wu H, Shen X, Xu S, Guo X, Bolick ML, Wu S, Wang F

Our previous works disclosed the contributing role of macrophage migration inhibitory factor (MIF) and dopaminergic inhibition by lysine dimethyltransferase G9a/Glp complex in peripheral nerve injury-induced hypersensitivity. We herein propose that...
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