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How an Occluded Artery Recanalizes during Acute Stroke Thrombolysis

Sharma VK, Yeo LL, Teoh HL

No abstract available.
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Giant Carotid Pseudoaneurysm

Yeo LL, Wong J, Paliwal P, Majumder A, Chee EY, Ting E, Sharma VK

No abstract available.
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Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratios Are Associated with Recurrent Ischemic Stroke in Patients with Embolic Stroke of Undetermined Source

Li TY, Sia CH, Chan BP, Ho JS, Leow AS, Chan MY, Kojodjojo P, Galupo MJ, Teoh HL, Sharma VK, Seet RC, Yeo LL, Tan BYQ

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Determination of levels of nitric oxide in smoker and nonsmoker patients with chronic periodontitis

Wadhwa D, Bey A, Hasija M, Moin S, Kumar A, Aman S, Sharma VK

PURPOSE: Cigarette smoking is a major risk factor in periodontal diseases. The pathogenesis of periodontal diseases may be affected by alterations of the inflammatory response by smoke. Nitric oxide (NO)...
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Non-alcoholic fatty liver disease increases risk of carotid atherosclerosis and ischemic stroke: An updated meta-analysis with 135,602 individuals

Tang ASP, Chan KE, Quek J, Xiao J, Tay P, Teng M, Lee KS, Lin SY, Myint MZ, Tan B, Sharma VK, Tan DJH, Lim WH, Kaewdech A, Huang D, Chew NW, Siddiqui MS, Sanyal AJ, Muthiah M, Ng CH

Background/Aims: Non-alcoholic fatty liver disease (NAFLD) is associated with the development of cardiovascular disease. While existing studies have examined cardiac remodeling in NAFLD, there has been less emphasis on the...
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Ethnic Differences in the Safety and Efficacy of Tenecteplase Versus Alteplase for Acute Ischemic Stroke: A Systematic Review and Meta-Analysis

Koh JH, Lim CYJ, Tan LTP, Sia CH, Poh KK, Sharma VK, Yeo LLL, Ho AFW, Wu T, Kong WKF, Tan BYQ

Background and Purpose Tenecteplase is a thrombolytic agent with pharmacological advantages over alteplase and has been shown to be noninferior to alteplase for acute ischemic stroke in randomized trials. However,...
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Bridging Thrombolysis versus Direct Mechanical Thrombectomy in Stroke Due to Basilar Artery Occlusion

Siow I, Y.Q. Tan B, Lee KS, Ong N, Toh E, Gopinathan A, Yang C, Bhogal P, Lam E, Spooner O, Meyer L, Fiehler J, Papanagiotou P, Kastrup A, Alexandrou M, Zubel S, Wu Q, Mpotsaris A, Maus V, Anderson T, Gontu V, Arnberg F, Lee TH, Chan BP, Seet RC, Teoh HL, Sharma VK, Yeo LL

Background and Purpose Mechanical thrombectomy (MT) is an effective treatment for patients with basilar artery occlusion (BAO) acute ischemic stroke. It remains unclear whether bridging intravenous thrombolysis (IVT) prior to...
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Timing of Recanalization and Functional Recovery in Acute Ischemic Stroke

Tsivgoulis G, Saqqur M, Sharma VK, Brunser A, Eggers J, Mikulik R, Katsanos A, Sergentanis TN, Vadikolias K, Perren F, Rubiera M, Bavarsad Shahripour R, Nguyen HT, Martínez-Sánchez P, Safouris A, Heliopoulos I, Shuaib A, Derksen C, Voumvourakis K, Psaltopoulou T, Alexandrov AW, Alexandrov AV, CLOTBUST-PRO investigators

Background and Purpose Although onset-to-treatment time is associated with early clinical recovery in acute ischemic stroke (AIS) patients treated with intravenous tissue plasminogen activator (tPA), the effect of the timing...
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