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Emerging Pharmacologic Therapies for Constipation-predominant Irritable Bowel Syndrome and Chronic Constipation

Eswaran S, Guentner A, Chey WD

  • KMID: 2381166
  • J Neurogastroenterol Motil.
  • 2014 Apr;20(2):141-151.
Irritable bowel syndrome with constipation and chronic functional constipation are common digestive disorders that negatively impact quality of life and account for billions of dollars in health care costs. Related...
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Characteristics of 5-Hydroxytryptamine Receptors Involved in Contraction of Feline Ileal Longitudinal Smooth Muscle

Wang Y, Park SY, Oh KH, Min Y, Lee YJ, Lee SY, Sohn UD

A number of studies have demonstrated that 5-hydroxytryptamine (5-HT) can induce muscle contraction or relaxation response and enhance secretion in the gastrointestinal tract via a multiplicity of 5-HT receptor subtypes....
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Serotonin syndrome associated with linezolid

Jeon DS, Nam YH, Kim SH, Choi WJ, Kim EB, Lee HW, Nam HJ, Song JE, Lee SK

Serotonin syndrome (SS) is a potentially life-threatening drug reaction characterized by mental status change, increased neuromuscular tone, and autonomic instability. Linezolid, an oxazolidinone antibacterial agent, is widely used in general...
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Double-Blind Placebo-Controlled Randomized Clinical Trial of Zolmitriptan in Acute Treatment of Migraine

Lee SB, Kim YI, Choi YB, Chung SW, Yang DW, Lee KS, Kwon SU, Kim JS, Kim BS

  • KMID: 1812913
  • J Korean Neurol Assoc.
  • 2001 Jan;19(1):29-35.
BACKGROUND: Zolmitriptan (Zomig) is a selective serotonin agonist at the 5-hydroxytryptamine (5-HT1B/1D) receptor that acts both centrally and peripherally in the trigeminal nucleus and axon terminals and at adjacent meningeal...
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Effects of Opioid Agonists on the Suppressed Spontaneous Alternation Behaviour in Rats

Lee GC, Jeon SI, Lee JH, Choi YM, Kim SH, Ryu JH, Choi M, Chang HI

  • KMID: 2334619
  • J Korean Soc Biol Psychiatry.
  • 1999 Nov;6(2):193-201.
This study was designed to evaluated the effects of opioid receptor agonists on the spontaneous alternation behaviour in an animal model of obsessive-compulsive disorder in rats. According to the theory...
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Effects of the Clozapine on the Suppressed Spontaneous Alternation Behaviour in Rats

Cheon KH, Lee GC, Lee JH, Choi YM, Jeon SI, Jung HK, Ryu JW, Choi M

  • KMID: 2340211
  • J Korean Neuropsychiatr Assoc.
  • 1998 Sep;37(5):983-991.
OBJECTIVES: The study was designed to evaluate the role of the 5-HT2 and dopanmine D2 antagonist on spontaneous alternation behaviour which is an animal model of obsessive compulsive disorder in...
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Current Issues in Functional Dyspepsia

Park JK, Huh KC, Shin CM, Lee H, Yoon YH, Song KH, Min BH, Choi KD, The Korean Society of Neurogastroenterology and Motility

Functional dyspepsia is one of the most common gastrointestinal disorders encountered in clinical practice. Functional dyspepsia is currently defined by Rome III criteria as the chronic dyspeptic symptoms (postprandial fullness,...
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Hiccup: Mystery, Nature and Treatment

Chang FY, Lu CL

  • KMID: 2325876
  • J Neurogastroenterol Motil.
  • 2012 Apr;18(2):123-130.
Hiccup is the sudden onset of erratic diaphragmatic and intercostal muscle contraction and immediately followed by laryngeal closure. The abrupt air rush into lungs elicits a "hic" sound. Hiccup is...
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