- Serotonin Transporter Gene Polymorphism and Irritable Bowel Syndrome
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Park JM, Choi MG
- KMID: 2307483
- Korean J Neurogastroenterol Motil.
- 2007 Jun;13(1):97-98.
No abstract available. -
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- Investigation into the Possible Genetic Role of Serotonin and Dopamine Transporters in Psychological Resilience
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Cho SH, Chung JK, Bang YW, Joo EJ
- KMID: 2434818
- Korean J Biol Psychiatry.
- 2018 Feb;25(1):16-20.
- doi: 10.0000/kjbp.2018.25.1.16
OBJECTIVES: Psychological resilience is the ability to cope with stress. The genetic background behind psychological resilience is not much known. The serotonin transporter and dopamine transporter are implicated in stress... -
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- Pharmacogenomics of Antidepressants
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Han CS, Kim SH
- KMID: 1985324
- Korean J Psychopharmacol.
- 2002 Jun;13(2):75-84.
In an approach known as pharmacogenomics, many psychopharmacologists hope to match depressive patients to specific drugs based on the patients' genetic profiles. Many researchers and pharmaceutical companies are investing their... -
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- Current Understanding in Neurobiology of Depressive Disorders: Imaging Genetic Studies on Serotonin Transporter
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Ham BJ
- KMID: 2299889
- Korean J Biol Psychiatry.
- 2011 Nov;18(4):176-180.
Depressive disorders have strong genetic components. However, conventional linkage and association studies have not yielded definitive results. These might be due to the absence of objective diagnostic tests, the complex... -
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- Radiopharmaceuticals for Neurotransmitter Imaging
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Oh SJ
- KMID: 2313032
- Nucl Med Mol Imaging.
- 2007 Apr;41(2):118-131.
Neurotransmitter imaging with radiopharmaceuticals plays major role for understanding of neurological and psychiatric disorders such as Parkinson's disease and depression. Radiopharmaceuticals for neurotransmitter imaging can be divided to dopamine transporter... -
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- Early Treatment Response of Bupropion SR in Smoking Cessation according to Genetic Polymorphism and Temperamental Characteristics
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Lee YS, Kim SY, Han DH, Min KJ, Na C
- KMID: 2287243
- Korean J Psychopharmacol.
- 2006 Mar;17(2):219-228.
OBJECTIVE: Bupropion is an antidepressant with proven efficacy for smoking cessation, however the response rate is some limited. With this background, the authors investigated the difference of early bupropion response... -
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- Association between Social Phobia and Serotonin Transporter Gene Polymorphism: Preliminary Study
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Lee JH, Lim SW, Oh KS, Lee MS
- KMID: 1511825
- Korean J Biol Psychiatry.
- 2006 Aug;13(3):170-177.
ele frequency analysis, a significant association was also observed between the short allele and social phobia(p=.030). A significant associations between S genotype and each subgroup were observed(GEN p=.045 ; NGEN... -
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- Suicide : Gene-Environment Interaction
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Kim YK
- KMID: 2249836
- Korean J Biol Psychiatry.
- 2010 May;17(2):65-69.
Gene-environment interactions are important in pathogenesis of suicide or suicidal behavior. Twin and adoption studies and family studies show that genetic factors play a critical role in suicide or suicidal... -
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- Effect of Sertraline on the Regulation of Serotonin Transporter mRNA Levels in Rat Brain
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Kim CY, Kim SY, Hong JP, Lee C, Hwang OY, Han OS
- KMID: 2340366
- J Korean Neuropsychiatr Assoc.
- 1999 Sep;38(5):1071-1076.
The knowledge of gene regulation of serotonin transporter mRNA may provide clues to understanding how antidepressants affect their therapeutic actions. Recently, the effects of antidepressants on the serotonin transporter have... -
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- Serotonin Transporter Gene Polymorphism and its Relationship to Plasma Serotonin in Irritable Bowel Syndrome
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Park H, Lee DY, Kim MS, Choi EJ, Kim YG, Ji SW, Lee SI
- KMID: 2307529
- Korean J Neurogastroenterol Motil.
- 2004 Dec;10(2):125-129.
BACKGROUND/AIMS: Serotonin is an important mediator of intestinal peristalsis and it undergoes reuptake by a transporter protein (SERT). It has been reported that polymorphisms in the promoter for synthesis of... -
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- Serotonin Transporter and Pharmacotherapy
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Kim SJ, Seok JH, Kim CH
- KMID: 2287361
- Korean J Psychopharmacol.
- 2006 May;17(3):263-272.
The serotonin transporter (SERT) is the target site for serotonin reuptake inhibitors, which are the most widely used agents for treating various psychiatric diseases including depression. The SERT is a... -
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- Central Nervous System Drug Evaluation Using Positron Emission Tomography
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Sekine M, Maeda J, Shimada H, Nogami T, Arakawa R, Takano H, Higuchi M, Ito H, Okubo Y, Suhara T
- KMID: 2171280
- Clin Psychopharmacol Neurosci.
- 2011 Apr;9(1):9-16.
In conventional pharmacological research in the field of mental disorders, pharmacological effect and dose have been estimated by ethological approach and in vitro data of affinity to the site of... -
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- Association between the Genetic Polymorphisms of the Biogenic Amine Transporters and the Antidepressant Responsiveness in Korean Depressed Patients
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Kim DK, Kim EJ, Lim SW, Kim H
- KMID: 2287338
- Korean J Psychopharmacol.
- 2003 Sep;14(3):274-283.
OBJECTIVE: Serotonin transporter (5-HTT) is a key synaptic regulator of serotonergic neurotransmission and a major site of action of most antidepressants. The functional polymorphism of 5-HTT gene is reported to... -
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- 5-HT Transporter and Mood Disorder
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Lee MS
- KMID: 2202802
- J Korean Soc Biol Psychiatry.
- 2001 Nov;8(2):220-225.
As numbers of serotonin's function are so many, studies of serotonin are numerous nowadays. In the beginning, concentration of metabolites such as 5-HIAA was a key issue, but recent studies... -
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- Biological and Genetic Prediction Factors Associated with Suicidal Behavior
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Kim YK
- KMID: 2249005
- Korean J Biol Psychiatry.
- 2005 May;12(1):3-12.
Most suicides(about 90%) occur in the context of psychiatric disorders. Prediction of suicide risk in patients with mental illness is very important in preventing suicide attempts. However, current approaches to... -
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- Serotonin Transporter Gene and G-protein beta3 C825T Gene Polymorphism in Patients with Functional Dyspepsia and Irritable Bowel Syndrome
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Park HY, Jahng JH, Lee YJ, Park H, Lee SI
- KMID: 2307425
- Korean J Neurogastroenterol Motil.
- 2009 Jun;15(1):58-64.
BACKGROUND/AIMS: The pathogenesis of functional dyspepsia (FD) and irritable bowel syndrome (IBS) is considered to be multifactorial. Recently, several candidate genetic studies have suggested that serotonin transporter (SERT) gene polymorphism... -
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- Association between Obsessive-Compulsive Disorder and Serotonin Transporter Gene Polymorphism
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Kim SJ, Kim CH, Cho DY, Lee HS
- KMID: 2341062
- J Korean Neuropsychiatr Assoc.
- 2005 Jan;44(1):41-49.
OBJECTIVES: The definite cause of obsessive-compulsive disorder (OCD) is still unknown. Evidences from familial, twin and segregation studies support the role of a genetic factor. There also are growing evidences... -
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- An Update on Post-infectious Irritable Bowel Syndrome: Role of Genetics, Immune Activation, Serotonin and Altered Microbiome
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Spiller R, Lam C
- KMID: 2325919
- J Neurogastroenterol Motil.
- 2012 Jul;18(3):258-268.
The literature on post-infectious irritable bowel syndrome (IBS) is reviewed with special emphasis on recent new data. Further accounts of this phenomenon continue to be reported following a range of... -
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- Neurobiology of Depression
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Kim YH, Lee SK, Rhee CG, Kim JI
- KMID: 2334586
- J Korean Soc Biol Psychiatry.
- 1999 Jul;6(1):3-11.
At the beginning, researches on the biology of depression or affective illness have focused mainly on the receptor functions and neuroendocrine activities. And the studies of the past years did... -
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- The Use of Pharmacogenomic Method for the Prediction of Antidepressant Responsiveness
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Kim DK, Lim SW
- KMID: 2202793
- J Korean Soc Biol Psychiatry.
- 2002 Jul;9(1):25-33.
Serotonin transporter(5-HTT) is one of the major action site of antidepressants in neuronal cells. According to the recent studies, it is known that the functional polymorphism in the promoter region... -
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