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Activation of Eosinophils with Airborne Fungi

Shin SH, Kim JK, Kita H

  • KMID: 2276174
  • Korean J Otolaryngol-Head Neck Surg.
  • 2004 Jun;47(6):549-553.
BACKGROUND AND OBJECTIVES: Allergic fungal sinusitis is characterized by allergic mucin which includes eosinophils and fungal hyphae. But we don't know why eosinophils are accumulated at the nasal secretion and...
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Protease from Airborn Fungi Induce Activation of Nasal Epithelial Cells

Shin SH, Park GU, Jeon CH

  • KMID: 2037116
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Feb;48(2):189-194.
BACKGROUND AND OBJECTIVES: The nasal epithelium is the first barrier encountered by airborne allergens and an active participant in airway inflammation. Fungi have been increasingly recognized as important pathogens in...
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Clinical Improvement of Atopic Dermatitis by a Topical Cream Containing a Protease-Activated Receptor-2 (PAR-2) Inhibitor 'Pal-KTTKS Peptide'

Lee Y, Kim M, Kong ID, Ryu J, Jang M, Lee C, Choi EH

  • KMID: 2301807
  • Korean J Dermatol.
  • 2010 Nov;48(11):966-974.
BACKGROUND: Serine protease promotes desquamatation of the stratum corneum and this is controlled by serine protease inhibitors (SPI). After disruption of the skin barrier, signals for barrier recovery are started...
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The Serine Protease Inhibitor, 4-(2-aminoethyl) Benzene Sulfonyl Fluoride Hydrochloride, Reduces Allergic Inflammation in a House Dust Mite Allergic Rhinitis Mouse Model

Kim BY, Park HR, Shin JH, Kim SW, Cho JH, Park YJ, Kim SW

PURPOSE: Serine protease inhibitors are involved in immune development, anti-inflammatory mechanisms, and tissue repair. In the present study, the serine protease inhibitor 4-(2-aminoethyl) benzene sulfonyl fluoride hydrochloride (AEBSF) was evaluated...
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Urinary trypsin inhibitor attenuates lipopolysaccharide-induced neutrophil activation

Lee SH, Kim HJ, Han HJ, Li M, Kwak SH, Park S

BACKGROUND: Urinary trypsin inhibitor (UTI), which is speculated to have anti-inflammatory effects, is one of serine protease inhibitors found in human urine and blood. The present study was conducted to...
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Immunoresuscitation Effect on Hemorrhagic Shock-Induced Acute Lung Injury in Rats

Park SH, Lee MJ, Jo KH, Kim YG

  • KMID: 2333112
  • J Korean Soc Emerg Med.
  • 2012 Apr;23(2):270-278.
PURPOSE: Recent studies have indicated that cytokines and inflammatory responses are related to hemorrhagic shock-(HS) induced acute lung injury. Novel, synthetic, broad-acting serine protease inhibitors that protect a wide range...
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Could Nafamostat or Gabexate Prevent the Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis?

Kwon YH, Kim JY, Lee SJ, Jang SY, Park HW, Yang HM, Jung MK, Jeon SW, Cho CM, Tak WY, Kweon YO, Kim SK

BACKGROUND/AIMS: ERCP is the most common procedure for the diagnosis and treatment of bile duct and pancreatic disease, but Post-ERCP pancreatitis makes poor outcome in some cases. The protease inhibitors,...
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