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Congenital Absence of Left Circumflex Coronary Artery: Circumflex Artery Extended from Right Coronary Artery

Park JW, Cha KS, Park SW, Lee SH, Seo IA, Lee CJ, Lee JH, Kim BK, Kim MH, Kim YD, Kim JS

Nonvisualization of left circumflex coronary artery from the left coronary artery is commonly due to anomalous origin of circumflex artery from the right coronary artery or right sinus of Valsalva....
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Tyrphostin ErbB2 Inhibitors AG825 and AG879 Have Non-specific Suppressive Effects on gp130/ STAT3 Signaling

Lee HK, Seo IA, Lee SH, Seo SY, Kim KS, Park HT

Although the interaction between gp130 and the ErbB family has frequently been shown in cancer cells, the mechanism of this interaction remains unclear and controversial. In the present study, we...
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Type 1 Lissencephaly with Ocular Abnormality and Cranial Nerve Palsies

Seo IA, Cho SY, Choi SM

Lissencephaly is a cerebral cortical malformation characterized by partial to total loss of gyri and sulci of brain leading to mental retardation and epilepsy. It is caused by failure of...
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Immunohistochemical Study on the Distribution of Tumor Endothelial Marker 7 in the Rat Forebrain

Kang DS, Lee HK, Park HK, Seo IA, Lee KY, Park HT

  • KMID: 2092840
  • Korean J Anat.
  • 2004 Oct;37(5):441-448.
Tumor endothelial marker 7 (TEM7) is a putative transmembrane protein that is highly expressed in the tumor endothelium. In the present study, the expression profile of TEM7 in the rat...
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Netrin-1 Specifically Enhances Cell Spreading on Fibronectin in Human Glioblastoma Cells

Lee HK, Seo IA, Shin YK, Lee SH, Seo SY, Suh DJ, Park HT

Netrins are secreted molecules and involved in axon guidance, cell migration and tumor development. Recent studies revealed that netrins perform novel functions in such processes as epithelial development and angiogenesis...
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Aneurysm of Sinus of Valsalva Dissecting into Interventricular Septum: A Possible Cause of Complete Atrioventricular Block

Seo IA, Cha KS, Oh IH, Lim JH, Song KH, Kim SG, Kim MH, Park HK, Kim YD, Woo JS, Kim JS

Dissection of the interventricular septum by aneurysm of sinus of Valsalva is a rare lesion and has poor prognosis. However, it can be diagnosed noninvasively with echocardiography and managed well...
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Nidogen Plays a Role in the Regenerative Axon Growth of Adult Sensory Neurons Through Schwann Cells

Lee HK, Seo IA, Suh DJ, Park HT

We previously reported that nidogen is an extracellular matrix protein regulating Schwann cell proliferation and migration. Since Schwann cells play a critical role in peripheral nerve regeneration, nidogen may play...
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Small Circumscribed Aortic Dissection Complicating Annuloaortic Ectasia in a Non-Marfanoid Patient

Park TH, Cha KS, Kim HK, Seo IA, Yun UD, Lim JH, Kim MH, Kim YD, Kim JS

Annuloaortic ectasia, cystic medial degeneration of the afflicted aortic wall leading to progressive dilatation, is often accompanied by Marfan's syndrome. Some portions of intimal flap is commonly demonstrated along the...
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Clinical Applications of Three-Dimensional Echocardiography

Kim BS, Park JW, Park HY, Park TH, Seo IA, Moon CH, Kim JH, Kim HK, Cha KS, Kim MH, Kim JS

  • KMID: 2101268
  • J Korean Soc Echocardiogr.
  • 1997 Dec;5(2):147-153.
BACKGROUND: Three-dimensional echocardiography has good feasibility and real image display in dynamic and spatial cardiac structures. So we designed this study to assess both the feasibility and potential role of...
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Postnatal Developmental Expression of TEM7 mRNA and its Putative Ligand in the Rat Cerebellum

Kang DS, Seo IA, Lee HK, Chung JY, Kim JM, Lee KY, Park HT

  • KMID: 2092865
  • Korean J Anat.
  • 2005 Oct;38(5):469-475.
Tumor endothelial marker 7 (TEM7) is a putative transmembrane protein that is highly expressed in the tumor endothelium and cerebellar neurons. In the present study, the expression profile of TEM7...
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Janus Kinase 2 Inhibitor AG490 Inhibits the STAT3 Signaling Pathway by Suppressing Protein Translation of gp130

Seo IA, Lee HK, Shin YK, Lee SH, Seo SY, Park JW, Park HT

The binding of interleukin-6 (IL-6) cytokine family ligands to the gp130 receptor complex activates the Janus kinase (JAK)/ signal transducer and activator of transcription 3 (STAT3) signal transduction pathway,...
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Insulin Secretory Dysfunction in the Pathogenesis of Type 2 Diabetes in Koreans: A Minimal Model Analysis

Kim SH, Kim DJ, Lee BW, Seo IA, Chung JH, Min YK, Lee MS, Kim KW, Lee MK

  • KMID: 1515210
  • J Korean Diabetes Assoc.
  • 2003 Oct;27(5):414-419.
BACKGROUND: Type 2 diabetes is a complex, heterogeneous disorder, characterized by impairments in both insulin secretion and insulin action. This study was done to examine the significance of alterations in...
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Netrin Inhibits Regenerative Axon Growth of Adult Dorsal Root Ganglion Neurons in Vitro

Park JI, Seo IA, Lee HK, Park HT, Shin SW, Park YM, Ahn KJ

Netrin is a neuronal guidance molecule implicated in the development of spinal commissural neurons and cortical neurons. The attractive function of netrin requires the receptor, Deleted in Colorectal Cancer (DCC),...
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Early Detection of Kawasaki Disease in Infants

Kang JH, Hong SJ, Seo IA, Kwak MH, Cho SM, Kim DK, Choi SM, Lee DS

BACKGROUND AND OBJECTIVES: This study aimed to investigate the clinical characteristics of infantile Kawasaki disease (KD), and to evaluate early diagnostic features of KD in febrile infants. SUBJECTS AND METHODS: We...
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Re-transplantation of Pancreatic Islets in Insulin Dependent Diabetes Mellitus

Yang TY, Oh SH, Jeong IK, Seo IA, Oh EY, Cho GY, Kim SJ, Chung JH, Min YK, Lee MS, Lee MK, Kim KW, Do YS, Choo SW

  • KMID: 1905891
  • J Korean Diabetes Assoc.
  • 2000 Aug;24(4):457-466.
BACKGROUND: Over the past 20 years, significant advances have been made in human islet transplantaiton. However, cases of prolonged insulin independence after islet allotransplantation have rarely been reported and over...
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