- No Evidence of an Association between A218C Polymorphism of the Tryptophan Hydroxylase 1 Gene and Aggression in Schizophrenia in a Korean Population
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Kim YR, Lee JY, Min SK
- KMID: 1779602
- Yonsei Med J.
- 2010 Jan;51(1):27-32.
- doi: 10.3349/ymj.2010.51.1.27
PURPOSE: We investigated the association between the tryptohan hydroxylase 1 (TPH1) gene and aggression in schizophrenia in a Korean population. MATERIALS AND METHODS: The sample included 61 aggressive patients as... -
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- No Association of Functional Polymorphisms in Methlylenetetrahydrofolate Reductase and the Risk and Minor Physical Anomalies of Schizophrenia in Korean Population
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Kim SG, Song JY, Joo EJ, Jeong SH, Kim SH, Lee KY, Lee NY, Ahn YM, Kim YS, Roh MS
- KMID: 1785995
- J Korean Med Sci.
- 2011 Oct;26(10):1356-1363.
- doi: 10.3346/jkms.2011.26.10.1356
Methylenetetrahydrofolate reductase (MTHFR), a critical enzyme in folate metabolism, plays an important role in DNA methylation. It has been suggested that abnormal DNA methylation contributes to the pathogenesis of schizophrenia... -
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- Associations between DRDs and schizophrenia in a Korean population: multi-stage association analyses
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Lee KY, Joo EJ, Ji YI, Kim DH, Park J, Chung IW, Lee SI, Joo YH, Ahn YM, Song JY, Kim YS
- KMID: 991622
- Exp Mol Med.
- 2011 Jan;43(1):44-52.
- doi: 10.3858/emm.2011.43.1.005
The dysregulation of the dopaminergic system has been implicated in the pathophysiology of major psychosis, including schizophrenia, with dopamine receptor genes (DRDs) presently targeted as the most promising candidate genes.... -
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