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Recurrent and Drastic Increase in Dabigatran Levels May Be Induced by Therapeutic Plasma Exchange

Pflug MA, Schellinger PD

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Percutaneous Left Atrial Appendage Occlusion for the Prevention of Stroke in Patients with Atrial Fibrillation: Review and Critical Appraisal

Schellinger PD, Tsivgoulis G, Steiner T, Köhrmann

The authors review the current status of percutaneous left atrial appendage (LAA) occlusion therapy in patients with atrial fibrillation with the goal to prevent ischemic stroke and systemic embolism and...
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Patent Foramen Ovale: Story Closed?

Köhrmann , Schellinger PD, Tsivgoulis G, Steiner T

The optimal treatment strategy for secondary prevention in patients with cryptogenic stroke and patent foramen ovale (PFO) has been a matter of controversy for decades. After three randomized trials failed...
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Non-Vitamin K Oral Anticoagulants Associated Bleeding and Its Antidotes

Steiner T, Köhrmann , Schellinger PD, Tsivgoulis G

Oral anticoagulant-associated intracerebral hemorrhage (OAC-ICH) accounts for nearly 20% of all ICH. The number of patients with an indication for oral anticoagulant therapy (OAT) increases with increasing age. OAT became...
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Duration of Implantable Cardiac Monitoring and Detection of Atrial Fibrillation in Ischemic Stroke Patients: A Systematic Review and Meta-Analysis

Tsivgoulis G, Katsanos A, Köhrmann , Caso V, Perren F, Palaiodimou L, Deftereos , Giannopoulos S, Ellul J, Krogias C, Mavridis D, Triantafyllou S, Alexandrov AW, Schellinger PD, Alexandrov AV

BACKGROUND AND PURPOSE: Current guidelines do not provide firm directions on atrial fibrillation (AF) screening after ischemic stroke (IS). We sought to investigate the association of implantable cardiac monitoring (ICM)...
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Association of Elevated Blood Pressure Levels with Outcomes in Acute Ischemic Stroke Patients Treated with Intravenous Thrombolysis: A Systematic Review and Meta-Analysis

Malhotra K, Ahmed N, Filippatou A, Katsanos A, Goyal N, Tsioufis K, Manios E, Pikilidou , Schellinger PD, Alexandrov AW, Alexandrov AV, Tsivgoulis G

BACKGROUND AND PURPOSE: Although arbitrary blood pressure (BP) thresholds exist for acute ischemic stroke (AIS) patients eligible for intravenous thrombolysis (IVT), current international recommendations lack clarity on the impact of...
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