- Inhibitory effect of Mg2+ on the release of Ca2+ from Ryanodine receptor of the sarcoplasmic reticulum in the skeletal muscle
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Lee CJ
- KMID: 1686430
- Korean J Thorac Cardiovasc Surg.
- 1992 Apr;25(4):347-355.
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- Calcium Uptake and Release through Sarcoplasmic Reticulum in the Inferior Oblique Muscles of Patients with Inferior Oblique Overaction
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Kim HS, Chang YH, Kim DH, Park SR, Han SH, Lee JB
- KMID: 1110744
- Yonsei Med J.
- 2006 Apr;47(2):207-213.
- doi: 10.3349/ymj.2006.47.2.207
We characterized and compared the characteristics of Ca2+ movements through the sarcoplasmic reticulum of inferior oblique muscles in the various conditions including primary inferior oblique overaction (IOOA), secondary IOOA, and... -
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- Effect of excitability-inducing material on regenerative Ca++ release of rat ventricular muscle
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Kang DH, Lee YH, Song HJ
- KMID: 1729588
- Yonsei Med J.
- 1991 Sep;32(3):215-222.
- doi: 10.3349/ymj.1991.32.3.215
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- Effects of t-butyl hydrogen peroxide on single SR calcium release channels
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Shin JH, Kim KH, Suh CK
- KMID: 711527
- Yonsei Med J.
- 1998 Feb;39(1):56-60.
- doi: 10.3349/ymj.1998.39.1.56
Using lipid bilayer reconstitution technique, we investigated the oxidation effect of t-butyl hydrogen peroxide (tBHP) on the single channel activity of the sarcoplasmic reticulum (SR) calcium release channels isolated from... -
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- Skeletal Muscle Thermogenesis and Its Role in Whole Body Energy Metabolism
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Periasamy , Herrera JL, Reis FC
- KMID: 2392475
- Diabetes Metab J.
- 2017 Oct;41(5):327-336.
- doi: 10.4093/dmj.2017.41.5.327
Obesity and diabetes has become a major epidemic across the globe. Controlling obesity has been a challenge since this would require either increased physical activity or reduced caloric intake; both... -
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- Calcium cycling proteins in heartfailure, cardiomyopathy and arrhythmias
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Minamisawa S, Sato Y, Cho MC
- KMID: 1097100
- Exp Mol Med.
- 2004 Jun;36(3):193-203.
A growing body of evidence, including studies using genetically engineered mouse models, has shown that Ca2+ cycling and Ca2+ -dependent signaling pathways play a pivotal role in cardiac hypertrophy and... -
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- Minimal amount of insulin can reverse diabetic heart function: Sarcoplasmic reticulum Ca2+ transport and phospholamban protein expression
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Kim HW, Cho YS, Lee YS, Lee EH, Lee HR
- KMID: 1554136
- Korean J Physiol Pharmacol.
- 1999 Apr;3(2):175-182.
In the present study, the underlying mechanisms for diabetic functional derangement and insulin effect on diabetic cardiomyopathy were investigated with respect to sarcoplasmic reticulum (SR) Ca2+-ATPase and phospholamban at the transcriptional and translational... -
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- Ca2+-induced Ca2+ Release from Sarcoplasmic Reticulum Negatively Regulates Myocytic ANP Release in Beating Rabbit Atria
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Li D, Quan HX, Wen JF, Jin JY, Park SH, Kim SY, Kim SZ, Cho KW
- KMID: 2285314
- Korean J Physiol Pharmacol.
- 2005 Apr;9(2):87-94.
It is not clear whether Ca2+-induced Ca2+ release from the sarcoplasmic reticulum (SR) is involved in the regulation of atrial natriuretic peptide (ANP) release. Previously, we have shown that nifedipine... -
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- The Calcium and Voltage Clocks in Sinoatrial Node Automaticity
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Joung B, Ogawa M, Lin SF, Chen PS
- KMID: 1490696
- Korean Circ J.
- 2009 Jun;39(6):217-222.
- doi: 10.4070/kcj.2009.39.6.217
Recent evidence indicates that the voltage (cyclic activation and deactivation of membrane ion channels) and Ca2+ clocks (rhythmic spontaneous sarcoplasmic reticulum Ca2+ release) jointly regulate sinoatrial node (SAN) automaticity. Since... -
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- Changes in the Expressional Levels of Sarcoplasmic Reticulum Ca2+-regulatory Proteins in the Postnatal Developing Rat Heart
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Lee EH, Park SS, Lee JS, Seo YJ, Kim YH, Kim HW
- KMID: 1614999
- Korean J Physiol Pharmacol.
- 2002 Apr;6(2):101-108.
In the present study, the postnatal developmental changes in the expressional levels of cardiac sarcoplasmic reticulum (SR) Ca2+ regulatory proteins, i.e. Ca2+-ATPase, phospholamban, and Ca2+ release channel, were investigated. Both... -
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- Thyroid hormone-induced alterations of Ca2+-ATPase and phospholamban protein expression in cardiac sarcoplasmic reticulum
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Kim HW, Noh KM, Park M, Lee HR, Lee EH
- KMID: 1554148
- Korean J Physiol Pharmacol.
- 1999 Apr;3(2):223-230.
Alterations of cardiovascular function associated with various thyroid states have been studied. In hyperthyroidism left ventricular contractility and relaxation velocity were increased, whereas these parameters were decreased in hypothyroidism. The mechanisms for these changes... -
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- Decrease in Ca2+ storage in the cardiac sarcoplasmic reticulum of diabetic rat
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Kim WT, Kim HW, Kim YK
- KMID: 2071831
- Korean J Physiol Pharmacol.
- 1998 Dec;2(6):725-732.
In order to elucidate the molecular mechanism of the intracellular Ca2+ overload frequently reported from diabetic heart, diabetic rats were induced by the administration of streptozotocin, the membrane vesicles of junctional SR (heavy... -
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- Inhibition of Sarcoplasmic Reticulum Ca2+ Uptake by Pyruvate and Fatty Acid in H9c2 Cardiomyocytes: Implications for Diabetic Cardiomyopathy
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Lee EH, Lee HK, Kim HW, Kim YH
- KMID: 1600069
- Korean J Physiol Pharmacol.
- 2005 Aug;9(4):195-201.
High extracellular glucose concentration was reported to suppress intracellular Ca2+ clearing through altered sarcoplasmic reticulum (SR) function. In the present study, we attempted to elucidate the effects of pyruvate and... -
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- Studies on the roles of Na+/-Ca2+ exchange according to postnatal age in the negative staircase effect of the rat heart
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Lee HY, Kim SJ, Ko CM
- KMID: 2285189
- Korean J Physiol Pharmacol.
- 1997 Dec;1(6):707-716.
Recent reports revealed that the Na+/-Ca2+ exchangers and feet structures of sarcoplasmic reticulum (SR) are located in close vicinity in the specific compartment. Therefore, we investigated the possibility that the Na+/-Ca2+ exchanger may... -
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- Forward-mode Na+ - Ca2+ exchange during depolarization in the rat ventricular myocytes with high EGTA
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Kim EG, Ko CM
- KMID: 1607137
- Korean J Physiol Pharmacol.
- 2001 Dec;5(6):487-494.
During depolarization, extrusion of Ca2+ from sarcoplasmic reticulum through forward-mode Na+ - Ca2+ exchange was studied in the rat ventricular myocytes patch-clamped in whole-cell configuration. In order to confine the... -
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- Comparison of the determinants in the differences in force-frequency relationships between rat and rabbit left atria
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Ko CM, Kim SJ
- KMID: 1580940
- Korean J Physiol Pharmacol.
- 2000 Oct;4(5):417-425.
The underlying mechanism commonly applicable for both the positive and negative force-frequency relationships (FFR) was pursued in left atria (LA) of rat and rabbit. The species differences in the roles of Na+/Ca2+ exchanger... -
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- A focus on extracellular Ca²⺠entry into skeletal muscle
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Cho CH, Woo JS, Perez CF, Lee EH
- KMID: 2394309
- Exp Mol Med.
- 2017 Sep;49(9):e378.
- doi: 10.1038/emm.2017.208
The main task of skeletal muscle is contraction and relaxation for body movement and posture maintenance. During contraction and relaxation, Ca²⺠in the cytosol has a critical role in activating... -
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- Malignant Hyperthermia during General Anesthesia
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Kim TW, Chung HK, Kyoun IS
- KMID: 1934123
- Korean J Anesthesiol.
- 1992 Dec;25(6):1243-1249.
- doi: 10.4097/kjae.1992.25.6.1243
Malignant hyperthermia is a genetically transmitted, catastrophic, hypermetabolic syndrome that is induced by potent volatile anesthetics and/or depolarizing muscle relaxants. It is now well established that the pathophysiology is related... -
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- notropic and Electrophysiologic Effect of Azumolene in Intact Myocardium In Vitro
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Park WK, Kim KJ, Kim JH, Hong SJ
- KMID: 2091472
- Korean J Anesthesiol.
- 1999 Oct;37(4):685-693.
- doi: 10.4097/kjae.1999.37.4.685
BACKGROUND: The effects of various concentrations (10, 25 micrometer) of azumolene, an analogue of dantrolene, were studied in isolated guinea pig ventricular papillary muscles by measuring the effects on myocardial... -
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- Altered vascular calcium regulation in hypertension
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Kim WJ, Lee JU, Park YH, Nam SC
- KMID: 1554763
- Korean J Physiol Pharmacol.
- 1997 Oct;1(5):529-535.
The present study was aimed at investigating whether the vascular calcium regulation is altered in hypertension. Two-kidney, one clip (2K1C) and deoxycorticosterone acetate (DOCA)-salt hypertension were made in rats, and their thoracic aortae... -
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