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Erratum: Correction of Figures. The Time Course Changes in Bone Metabolic Markers after Administering the Anti-Receptor Activator of Nuclear Factor-Kappa B Ligand Antibody and Drug Compliance among Patients with Osteoporosis

Inage K, Orita S, Yamauchi K, Sakuma Y, Kubota G, Oikawa Y, Sainoh T, Sato J, Fujimoto K, Shiga Y, Takahashi , Ohtori S

There were some mistakes in the numerical values of the graphs.
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Response to: “Long-term Outcomes of In Situ Fusion for Treating Dysplastic Spondylolisthesis”

Inage K, Orita S, Yamauchi K, Suzuki M, Sakuma Y, Kubota G, Oikawa Y, Sainoh T, Sato J, Fujimoto K, Shiga Y, Abe K, Kanamoto H, Inoue M, Kinoshita , Norimoto M, Umimura T, Takahashi , Ohtori S

No abstract available.
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Improvements in Intractable Lumbar and LowerExtremity Symptoms after Systemic Administration of Tocilizumab, an Anti-interleukin-6 Receptor Antibody

Sainoh T, Sainoh T, Orita S, Orita S, Miyagi M, Miyagi M, Suzuki-Narita M, Suzuki-Narita M, Sakuma Y, Sakuma Y, Oikawa Y, Oikawa Y, Kubota G, Kubota G, Sato J, Sato J, Shiga Y, Shiga Y, Fujimoto K, Fujimoto K, Eguchi Y, Eguchi Y, Koda M, Koda M, Aoki Y, Aoki Y, Akazawa T, Akazawa T, Furuya T, Furuya T, Nakamura J, Nakamura J, Takahashi H, Takahashi H, Maki S, Maki S, Inoue M, Inoue M, Kinoshita H, Kinoshita H, Norimoto M, Norimoto M, Sato T, Sato T, Sato M, Sato M, Suzuki M, Suzuki M, Enomoto K, Enomoto K, Takaoka H, Takaoka H, Mizuki N, Mizuki N, Hozumi T, Hozumi T, Tsuchiya R, Tsuchiya R, Kim G, Kim G, Otagiri T, Otagiri T, Mukaihata T, Mukaihata T, Hishiya T, Hishiya T, Ohtori S, Ohtori S, Inage K, Inage K

Study Design: Prospective cohort study (open-label, single-arm, and non-blinded). Purpose: This study aims to determine the effects of systemic administration of tocilizumab, an anti-interleukin-6 (IL-6) receptor antibody on refractory low back...
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No Acceleration of Intervertebral Disc Degeneration after a Single Injection of Bupivacaine in Young Age Group with Follow-Up of 5 Years

Ohtori S, Inoue G, Orita S, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Nakamura J, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Takaso M, Toyone T, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Takahashi

STUDY DESIGN: Prospective study of changes in intervertebral disc degeneration after injection of bupivacaine. PURPOSE: To examine whether injection of bupivacaine into human intervertebral discs accelerates their degeneration. OVERVIEW OF LITERATURE: Bupivacaine...
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Interspinous Ligament Lidocaine and Steroid Injections for the Management of Baastrup's Disease: A Case Series

Okada K, Ohtori S, Inoue G, Orita S, Eguchi Y, Nakamura J, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Toyone T, Yamauchi K, Takahashi

STUDY DESIGN: Prospective study. PURPOSE: To examine the long-term effects of interspinous ligament injections of local anesthetics and steroids for the treatment of Baastrup's diseases. OVERVIEW OF LITERATURE: Baastrup's disease is associated...
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Clinical Incidence of Sacroiliac Joint Arthritis and Pain after Sacropelvic Fixation for Spinal Deformity

Ohtori S, Sainoh T, Takaso M, Inoue G, Orita S, Eguchi Y, Nakamura J, Aoki Y, Ishikawa T, Miyagi M, Arai G, Kamoda H, Suzuki M, Kubota G, Sakuma Y, Oikawa Y, Yamazaki M, Toyone T, Takahashi

PURPOSE: Sacroiliac fixation using iliac screws for highly unstable lumbar spine has been reported with an improved fusion rate and clinical results. On the other hand, there is a potential...
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Injection of Bupivacaine into Disc Space to Detect Painful Nonunion after Anterior Lumbar Interbody Fusion (ALIF) Surgery in Patients with Discogenic Low Back Pain

Kimura S, Ohtori S, Orita S, Inoue G, Eguchi Y, Takaso M, Ochiai N, Kuniyoshi , Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Sakuma Y, Kubota G, Oikawa Y, Inage K, Sainoh T, Yamauchi K, Toyone T, Nakamura J, Kishida S, Sato J, Takahashi

  • KMID: 2386481
  • Yonsei Med J.
  • 2014 Mar;55(2):487-492.
PURPOSE: Bupivacaine is commonly used for the treatment of back pain and the diagnosis of its origin. Nonunion is sometimes observed after spinal fusion surgery; however, whether the nonunion causes...
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Progressive Change in Joint Degeneration in Patients with Knee or Hip Osteoarthritis Treated with Fentanyl in a Randomized Trial

Fujii T, Takana K, Orita S, Inoue G, Ochiai N, Kuniyoshi , Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Sakuma Y, Kubota G, Oikawa Y, Inage K, Sainoh T, Sato J, Yamauchi K, Toyone T, Nakamura J, Kishida S, Takahashi , Ohtori S

PURPOSE: Opioids improve pain from knee and hip osteoarthritis (OA) and decrease the functional impairment of patients. However, there is a possibility that opioids induce analgesia and suppress the physiological...
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Increase of TRPV1-Immunoreactivity in Dorsal Root Ganglia Neurons Innervating the Femur in a Rat Model of Osteoporosis

Yoshino K, Suzuki M, Kawarai Y, Sakuma Y, Inoue G, Orita S, Yamauchi K, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Kubota G, Oikawa Y, Inage K, Sainoh T, Sato J, Nakamura J, Toyone T, Takahashi , Ohtori S

PURPOSE: Transient receptor potential vanilloid 1 (TRPV1) is a ligand-gated nonselective cation channel, which can be activated by capsaicin and other noxious stimuli. Recently, an association between bone pain and...
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Comparison of Clinical and Radiologic Results of Mini-Open Transforaminal Lumbar Interbody Fusion and Extreme Lateral Interbody Fusion Indirect Decompression for Degenerative Lumbar Spondylolisthesis

Kono Y, Gen H, Sakuma Y, Koshika Y

STUDY DESIGN: Retrospective study. PURPOSE: In this study, we compared the postoperative outcomes of extreme lateral interbody fusion (XLIF) indirect decompression with that of mini-open transforaminal lumbar interbody fusion (TLIF) in...
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Transient Receptor Potential Vanilloid 1-Immunoreactive Innervation Increases in Fractured Rat Femur

Kawarai Y, Suzuki M, Yoshino K, Inoue G, Orita S, Yamauchi K, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Sato J, Nakamura J, Takaso M, Toyone T, Takahashi , Ohtori S

PURPOSE: Pain from vertebral or femoral neck fractures is a particularly important problem in clinical orthopaedics. Transient receptor potential vanilloid 1 (TRPV1) is a ligand-gated nonselective cation channel, and there...
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PainVision Apparatus Is Effective for Assessing Low Back Pain

Ohtori S, Kawaguchi , Takebayashi T, Orita S, Inoue G, Yamauchi K, Aoki Y, Nakamura J, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Sato J, Takahashi , Konno S

STUDY DESIGN: Case series. PURPOSE: To determine the utility of "PainVision" apparatus for the assessment of low back pain. OVERVIEW OF LITERATURE: A newly developed device, the PainVision PS-2100 (Nipro, Osaka, Japan),...
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The Time Course Changes in Bone Metabolic Markers after Administering the Anti-Receptor Activator of Nuclear Factor-Kappa B Ligand Antibody and Drug Compliance among Patients with Osteoporosis

Inage K, Orita S, Yamauchi K, Sakuma Y, Kubota G, Oikawa Y, Sainoh T, Sato J, Fujimoto K, Shiga Y, Takahashi , Ohtori S

STUDY DESIGN: Retrospective study. PURPOSE: We conducted a study to investigate the time course changes in bone metabolic markers after the administration of the anti-receptor activator of nuclear factor-kappa B ligand...
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Mini-Open Anterior Retroperitoneal Lumbar Interbody Fusion: Oblique Lateral Interbody Fusion for Lumbar Spinal Degeneration Disease

Ohtori S, Orita S, Yamauchi K, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Aoki Y, Nakamura J, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Sato J, Fujimoto K, Shiga Y, Abe K, Toyone T, Inoue G, Takahashi

PURPOSE: Surgery for lumbar spinal degeneration disease is widely performed. While posterior decompression and fusion are popular, anterior lumbar interbody fusion (ALIF) is also used for treatment. Extreme lateral interbody...
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Up-Regulation of Pain Behavior and Glial Activity in the Spinal Cord after Compression and Application of Nucleus Pulposus onto the Sciatic Nerve in Rats

Norimoto M, Sakuma Y, Suzuki M, Orita S, Yamauchi K, Inoue G, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Kubota G, Oikawa Y, Inage K, Sainoh T, Sato J, Nakamura J, Toyone T, Takahashi , Ohtori S

STUDY DESIGN: Experimental animal study. PURPOSE: To evaluate pain-related behavior and changes in glial activity in the spinal dorsal horn after combined sciatic nerve compression and nucleus pulposus (NP) application in...
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Efficacy of Combination of Meloxicam and Pregabalin for Pain in Knee Osteoarthritis

Ohtori S, Inoue G, Orita S, Takaso M, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzkuki M, Nakamura J, Kubota G, Sakuma Y, Oikawa Y, Toyone T, Inage K, Sainoh T, Yamauchi K, Takahashi

PURPOSE: Osteoarthritic pain is largely considered to be inflammatory pain. Sensory nerve fibers innervating the knee have been shown to be significantly damaged in rat models of knee osteoarthritis (OA)...
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Existence of a Neuropathic Pain Component in Patients with Osteoarthritis of the Knee

Ohtori S, Orita S, Yamashita , Ishikawa T, Ito T, Shigemura , Nishiyama , Konno S, Ohta H, Takaso M, Inoue G, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Aoki Y, Arai G, Miyagi M, Kamoda H, Suzkuki M, Nakamura J, Furuya T, Kubota G, Sakuma Y, Oikawa Y, Suzuki M, Sasho T, Nakagawa K, Toyone T, Takahashi

PURPOSE: Pain from osteoarthritis (OA) is generally classified as nociceptive (inflammatory). Animal models of knee OA have shown that sensory nerve fibers innervating the knee are significantly damaged with destruction...
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Evaluation of Behavior and Expression of Receptor Activator of Nuclear Factor-Kappa B Ligand in Dorsal Root Ganglia after Sciatic Nerve Compression and Application of Nucleus Pulposus in Rats

Matsuyama , Sakuma Y, Suzuki M, Orita S, Yamauchi K, Inoue G, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Kubota G, Oikawa Y, Inage K, Sainoh T, Sato J, Nakamura J, Toyone T, Takahashi , Ohtori S

STUDY DESIGN: Experimental animal study. PURPOSE: To evaluate pain-related behavior and changes in nuclear factor-kappa B (NF-kB), receptor activator of NF-kB (RANK), and ligand (RANKL) in dorsal root ganglia (DRG) after...
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Low-Dose Tramadol and Non-Steroidal Anti-Inflammatory Drug Combination Therapy Prevents the Transition to Chronic Low Back Pain

Inage K, Orita S, Yamauchi K, Suzuki T, Suzuki M, Sakuma Y, Kubota G, Oikawa Y, Sainoh T, Sato J, Fujimoto K, Shiga Y, Abe K, Kanamoto H, Inoue M, Kinoshita , Takahashi , Ohtori S

STUDY DESIGN: Retrospective study. PURPOSE: To determine whether low-dose tramadol plus non-steroidal anti-inflammatory drug combination therapy could prevent the transition of acute low back pain to chronic low back pain. OVERVIEW OF...
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Evaluation of Histological Changes in Back Muscle Injuries in Rats over Time

Abe K, Inage K, Sakuma Y, Orita S, Yamauchi K, Suzuki M, Kubota G, Oikawa Y, Sainoh T, Sato J, Fujimoto K, Shiga Y, Kanamoto H, Takahashi , Ohtori S

STUDY DESIGN: Animal model study. PURPOSE: The purpose of this study was to evaluate the histological variation in the injured muscle and production of calcitonin gene-related peptide in rats over time. OVERVIEW...
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