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Acetyl Eburicoic Acid from Laetiporus sulphureus var. miniatus Suppresses Inflammation in Murine Macrophage RAW 264.7 Cells

Saba E, Son Y, Jeon BR, Kim SE, Lee IK, Yun BS, Rhee MH

The basidiomycete Laetiporus sulphureus var. miniatus belongs to the Aphyllophorales, Polyporaceae, and grows on the needleleaf tree. The fruiting bodies of Laetiporus species are known to produce N-methylated tyramine derivatives,...
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Antioxidant and anti-inflammatory activities of Lespedeza cuneata in Coal fly ash-induced murine alveolar macrophage cells

Wahab A, Sim H, Choi K, Kim Y, Lee Y, Kang B, No YS, Lee D, Lee I, Lee J, Cha H, Kim SD, Saba E, Rhee MH

Lespedeza cuneata (LC) is a perennial plant used in herbal medicine to treat numerous diseases, including prostatic hyperplasia, diabetes, early atherosclerosis, and hematuria. Reference collections of bioactive compounds of LC...
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Artemisia capillaris Thunb. inhibits melanin synthesis activity via ERK-dependent MITF pathway in B16/F10 melanoma cells

Saba E, Oh MJ, Lee YY, Kwak D, Kim S, Rhee MH

Genus Artemisia occurs as a hardy plant and has a wide range of culinary and medicinal features. In this study, we aimed to describe the melanin inhibitory activity of one...
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Solanum lycopersicum (tomato) ethanol extract elicits anti-inflammatory effects via the nuclear factor kappa B pathway and rescues mice from septic shock

Saba E, Oh MJ, Kwak D, Roh SS, Kwon HW, Kim SD, Rhee MH

Solanum lycopersicum, commonly known as tomato, is widely used in raw, cooked, or liquid forms because it contains nutritional compounds that are beneficial for human health, including carotenoids, lycopene, ascorbic...
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Water soluble tomato concentrate regulates platelet function via the mitogen-activated protein kinase pathway

Jeong D, Irfan M, Saba E, Kim SD, Kim SH, Rhee MH

Tomato extract has been shown to exert antiplatelet activity in vitro and to change platelet function ex vivo, but with limitations. In this study, antiplatelet activity of water soluble tomato...
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