- The evolving understanding of histology as an endpoint in ulcerative colitis
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Akiyama S, Miyatani Y, Rubin DT
- KMID: 2560290
- Intest Res.
- 2024 Oct;22(4):389-396.
- doi: 10.5217/ir.2023.00120
A therapeutic goal for patients with ulcerative colitis (UC) is deep remission including clinical remission and mucosal healing. Mucosal healing was previously defined by endoscopic appearance, but recent studies demonstrate... -
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- Pouchitis in inflammatory bowel disease: a review of diagnosis, prognosis, and treatment
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Akiyama S, Rai V, Rubin DT
- KMID: 2512096
- Intest Res.
- 2021 Jan;19(1):1-11.
- doi: 10.5217/ir.2020.00047
Patients with inflammatory bowel disease (IBD) occasionally need a restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) because of medically refractory colitis or dysplasia/cancer. However, pouchitis may develop in up to... -
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- Enteric infections complicating ulcerative colitis
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Micic D, Hirsch A, Setia N, Rubin DT
- KMID: 2417662
- Intest Res.
- 2018 Jul;16(3):489-493.
- doi: 10.5217/ir.2018.16.3.489
Enteric infections have previously been postulated to play a role in the pathogenesis of inflammatory bowel disease (IBD), however, little evidence exists in the etiologic role of specific enteric infections... -
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- Histological inflammation increases the risk of colorectal neoplasia in ulcerative colitis: a systematic review
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Colman RJ, Rubin DT
- KMID: 2354961
- Intest Res.
- 2016 Jul;14(3):202-210.
- doi: 10.5217/ir.2016.14.3.202
BACKGROUND/AIMS: Ulcerative colitis (UC) patients are at greater risk for the development of colorectal neoplasia. Several individual studies have demonstrated associations between severity of histologic inflammation and colorectal neoplasia. However,... -
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- Vedolizumab for perianal fistulizing Crohn’s disease: systematic review and meta-analysis
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Ayoub F, Odenwald M, Micic D, Dalal SR, Pekow J, Cohen RD, Rubin DT, Sakuraba A
- KMID: 2529570
- Intest Res.
- 2022 Apr;20(2):240-250.
- doi: 10.5217/ir.2021.00091
Background/Aims: Perianal fistulas are a debilitating manifestation of Crohn’s disease (CD). Despite the advent of anti-tumor necrosis factor (anti-TNF) therapy, the medical management of fistulizing CD continues to be challenged... -
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- Factors associated with anti-tumor necrosis factor effectiveness to prevent postoperative recurrence in Crohn’s disease
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Buisson A, Cannon L, Umanskiy K, Hurst RD, Hyman NH, Sakuraba A, Pekow J, Dalal S, Cohen RD, Pereira B, Rubin DT
- KMID: 2531984
- Intest Res.
- 2022 Jul;20(3):303-312.
- doi: 10.5217/ir.2021.00018
Background/Aims: We assessed the effectiveness of anti-TNF agents and its associated factors to prevent endoscopic and clinical postoperative recurrence (POR) in Crohn’s disease (CD). Methods: From a prospectively-maintained database, we... -
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