- Eugenol Induces a Reactive Oxygen Species-mediated Apoptosis in HL-60 Human Promyelocytic Leukemia Cells
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Kil UH, Lee KH, Lee KT, Jin JY
- KMID: 2252340
- Korean J Hematol.
- 2005 Jun;40(2):65-74.
- doi: 10.5045/kjh.2005.40.2.65
BACKGROUND: Eugenol is a major component of the essential oil isolated from Eugenia caryophyllata (Myrtaceae), and has been widely used as a traditional medicine. In this study, the effects of... -
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- Alectinib (CH5424802) antagonizes ABCB1- and ABCG2-mediated multidrug resistance in vitro, in vivo and ex vivo
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Yang K, Chen Y, To KK, Wang F, Li D, Chen L, Fu L
- KMID: 2375790
- Exp Mol Med.
- 2017 Mar;49(3):e303.
- doi: 10.1038/emm.2016.168
Alectinib, an inhibitor of anaplastic lymphoma kinase (ALK), was approved by the Food and Drug Administration (FDA) for the treatment of patients with ALK-positive non-small cell lung cancer (NSCLC). Here... -
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- Establishment of Multi-Drug Resistance Functional Assay and Correlation of Multi-Drug Resistance Activity and Chemotherapeutic Outcomes in Patients with Acute Leukemia
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Park CJ, Kim MC, Han TJ, Seo EJ, Chi HS, Lee JH, Suh C, Lee KH, Kim WK
- KMID: 2083408
- Korean J Hematol.
- 2000 May;35(2):97-108.
BACKGROUND: Multi-drug resistance (MDR) is one of the most important obstacles in the chemotherapy of acute leukemia, so the modulators of MDR have been developed and tried. METHODS: We measured... -
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- Effect of quercetin on apoptosis of PANC-1 cells
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Lee JH, Lee HB, Jung GO, Oh JT, Park DE, Chae KM
- KMID: 2212545
- J Korean Surg Soc.
- 2013 Dec;85(6):249-260.
- doi: 10.4174/jkss.2013.85.6.249
PURPOSE: To investigate the chemotherapeutic effect of quercetin against cancer cells, signaling pathway of apoptosis was explored in human pancreatic cells. METHODS: Various anticancer drugs including adriamycin, cisplatin, 5-fluorouracil (5-FU) and... -
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- 5-FU Induces Apoptosis of Fas (+), HepG2 Cells Via Activation of Fas-mediated Caspase and Mitochondria Dysfunction
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Park C, Yoon KH, Lee YJ, Kim YK, Choi YC, Shin JH, Cho JH, Park R
- KMID: 1972955
- Cancer Res Treat.
- 2002 Apr;34(2):128-138.
PURPOSE: In order to investigate the role of Fas on the chemosensitivity of cancer cells in regards to chemotherapeutic agents, the Fas/FasL signaling pathway of apoptosis was explored in human... -
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- Melatonin Potentiates the Neuroprotective Properties of Resveratrol Against Beta-Amyloid-Induced Neurodegeneration by Modulating AMP-Activated Protein Kinase Pathways
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Kwon KJ, Kim HJ, Shin CY, Han SH
- KMID: 1462848
- J Clin Neurol.
- 2010 Sep;6(3):127-137.
- doi: 10.3988/jcn.2010.6.3.127
BACKGROUND AND PURPOSE: Recent studies have demonstrated that resveratrol (RSV) reduces the incidence of age-related macular degeneration, Alzheimer's disease (AD), and stroke, while melatonin (MEL) supplementation reduces the progression of... -
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