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Additive Effect of Diesel Exhaust Particulates and Ozone on Airway Hyperresponsiveness and Inflammation in a Mouse Model of Asthma

Jang AS, Choi IS, Takizawa H, Rhim TY, Lee JH, Park SW, Park CS

Allergic airway diseases are related to exposure to atmospheric pollutants, which have been suggested to be one factor in the increasing prevalence of asthma. Little is known about the effect...
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Proteomic Analysis of Differently Expressed Proteins in a Mouse Model for Allergic Asthma

Jeong HS, Rhim TY, Ahn MH, Yoon PO, Kim SH, Chung IY, Uh ST, Kim SI, Park CS

Allergic asthma is associated with persistent functional and structural changes in the airways and involves many different cell types. Many proteins involved in allergic asthma have been identified individually, but...
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Effects of Diesel Exhaust Particles on Airway Inflammation and Hyperresponsiveness in a Murine Model

  • KMID: 2299695
  • Korean J Asthma Allergy Clin Immunol.
  • 2005 Jun;25(2):117-122.
BACKGROUND: Epidemiologic studies show that increases in diesel exhaust particles (DEP) can aggravate acute asthma. However, there were a few asthma models in mice exposed to DEP. Nitric oxide (NO)...
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CpG methylation at GATA elements in the regulatory region of CCR3 positively correlates with CCR3 transcription

Uhm TG, Lee SK, Kim BS, Kang JH, Park CS, Rhim TY, Chang HS, Kim DJ, Chung IY

DNA methylation may regulate gene expression by restricting the access of transcription factors. We have previously demonstrated that GATA-1 regulates the transcription of the CCR3 gene by dynamically interacting with...
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Effects of Diesel Exhaust Particles on Airway Responsiveness and Remodeling in a Murine Asthma Model

  • KMID: 2299641
  • Korean J Asthma Allergy Clin Immunol.
  • 2006 Mar;26(1):70-77.
BACKGROUND: Epidemiologic and clinical investigations have suggested a strong link between particulate air pollution and asthma. The purpose of this study was to evaluate an effects of air pollutants on...
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