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Risk Factors of Potentially Inappropriate Medications and Cost by Polypharmacy among Elderly Patients of a Community Pharmacy near a Top Tier General Hospital

Kim A, Kim HA, Rhie SJ

OBJECTIVE: Polypharmacy is one of the main causes of inappropriate medication use, adverse drug-related events and cost. It aimed to investigate the status of polypharmacy and potentially inappropriate medication (PIM),...
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Improvement of Night Pharmacy Service by Automated Dispensing Cabinet System Implementation in Emergency Medical Center

Kim KH, Kim SA, Rhie SJ

OBJECTIVE: An automated process for medication preparation and dispensing is essential to improve the quality of work. To reduce night pharmacy workload, a new automated dispensing cabinet system was implemented...
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Erratum: Current View of Orphan Drug Usage in Tertiary Hospital and Rare Incurable Disease Hospital

Choi KS, Jeong YM, Kim YJ, Kim YH, Gu H, Lee BK, Lee E, Rhie SJ

Erratum agreed to by all authors, editor in chief, publisher, and scientific society.
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Practice Preferences on Dabigatran and Rivaroxaban for Stroke Prevention in Patients with Non-valvular Atrial Fibrillation

Park YK, Kang JE, Kim SJ, La HO, Rhie SJ

OBJECTIVE: Prescription rate of dabigatran and rivaroxaban, which are the direct oral anticoagulants (DOAC), has increased. We have analyzed the prescription trend and medication use of dabigatran and rivaroxaban in...
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Investigation and Development of Competency-based Training Program for Pharmacists in a Hospital

Kim MA, Kim SA, Park SH, Rhie SJ

OBJECTIVE: This study was to investigate and develop a training program that integrated and strengthened clinical competence and capacity of hospital pharmacists which would be implemented at the pharmacy department...
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Comparison of Propacetamol plus Fentanyl and Fentanyl alone with Patient Controlled Analgesia after Total Knee Arthroplasty

Kim M, Jeong H, Park S, Rhie SJ

OBJECTIVE: Opioid analgesics, for postoperative pain management, are an indispensable group of medication; however, they also have a variety of adverse drug reactions (ADR). Multimodal methods, combining non-opioid analgesics with...
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Patient Attitudes and Considerations in Decision toward Participation in Clinical Trials of Chronic Diseases

Yi J, Jang H, Yoon JH, Rhie SJ

BACKGROUND: We investigated the impact of financial compensation on patients' decision of participation in clinical trials and the related factors with patients' attitudes and considerations. METHODS: A survey questionnaire was placed...
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Effects of Adamantyl Derivatives on Pharmacokinetic Behavior of Paclitaxel in Rats

Kim KM, Lee K, Jang K, Moon YS, Lee HJ, Rhie SJ

Paclitaxel (PTX) is one of the most frequently used anticancer agent for treating refractory ovarian cancer, metastatic breast cancer and non-small cell lung cancer. However, its oral administration is impeded...
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Intranasal Insulin for Alzheimer's Disease and Amnestic Mild Cognitive Impairment: Systematic Review and Meta-analysis

Alnajjar S, Jin HK, Kang JE, Park SH, Rhie SJ

OBJECTIVE: There is recent evidence that insulin resistance is responsible for increasing the risk of developing cognitive dysfunction. To systematically review the influence of intranasal insulin treatment on the cognitive...
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Evaluation of Nivolumab Use and Factors related to Treatment Outcomes in a Cancer Center of a Top Tier General Hospital

Eoum G, Cho Y, Rhie SJ

BACKGROUND: We strived to evaluate the status of nivolumab use and associated factors on the clinical efficacy of the drug. METHODS: The study was retrospectively conducted in patients who had been...
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Prescription Patterns and Factors Related to the Number of Medications in Chronic Obstructive Pulmonary Disease in Non-elderly Adults

Moon CW, Ra HO, Rhie SJ

BACKGROUND: This study is to investigate the prescription patterns and factors related to the number of medications treating chronic obstructive pulmonary disease (COPD) in patients under 65 years old according...
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Comparison of Sugammadex and Neostigmine on First Spontaneous Breathing and Adverse Effects for Laparoscopic Cholecystectomy

Park H, Park MS, Kim MJ, Kim KS, Cho YS, Bae SS, Rhie SJ

OBJECTIVE: The purpose of the study was to investigate the time from the injection of muscle relaxants to the first spontaneous respiration between sugammadex and conventional reversal for patients undergoing...
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Drug Use Evaluation of Clostridium difficile Infection in Elderly Patients and Risk Factors of Non-improving Group

Noh HJ, Ham JY, Lee JG, Rhie SJ

OBJECTIVE: Clostridium difficile Infection (CDI) is one of the common nosocomial infections. As elderly population increases, the proper treatment has been emphasized. We investigated the risk factors associated with CDI...
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Current View of Orphan Drug Usage in Tertiary Hospital and Rare Incurable Disease Hospital

Choi KS, Jeong YM, Kim YJ, Kim YH, Gu H, Lee BK, Lee E, Rhie SJ

OBJECTIVE: Until now, there is minimal number of research for overall domestic status of orphan drug use in Korea. The purpose of this study is to identify the list of...
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Comparison of Histamine 2 Receptor Antagonists and Proton Pump Inhibitors on Infectious Complications in Critically Ill Patients

Park SY, Choi JH, Youn YJ, Rhie SJ

BACKGROUND: The use of acid suppressive agents became a standard therapy in an intensive care unit (ICU) to prevent stress related gastrointestinal mucosal damage. However, the risk of infectious diseases...
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Initiation of Pharmaceutical Care Service in Medical Intensive Care Unit with Drug Interaction Monitoring Program

Choi JH, Choi KS, Lee KS, Rhie SJ

OBJECTIVE: It is to evaluate the drug interaction monitoring program as a pilot project to develop a pharmaceutical care model in a medical intensive care unit and to analyze the...
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Virtual Global Collaboration to Advocate Students for Pharmacy Immunizations during Coronavirus Disease-19

Rhie SJ, Truong HA, Seo SW

Background: It was to describe collaborative educational efforts under Coronavirus disease 2019 period to advocate pharmacybased immunization delivery and meet unmet needs of...
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The Role of Oxidative Stress in Neurodegenerative Diseases

Kim GH, Kim JE, Rhie SJ, Yoon S

Oxidative stress is induced by an imbalanced redox states, involving either excessive generation of reactive oxygen species (ROS) or dysfunction of the antioxidant system. The brain is one of organs...
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Sports Pharmacy: New Specialty of Pharmacists and Pharmaceutical Care Services

Kim SH, Cho S, Choi JH, Lee YH, Rhie SJ

The World Anti-Doping Agency has made efforts to promote the safe use of medications and prevent doping in sports globally. International standards have been established and experts have advocate anti-doping...
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Molecular Neuroimaging in Posttraumatic Stress Disorder

Im JJ, Namgung E, Choi Y, Kim JY, Rhie SJ, Yoon S

Over the past decade, an increasing number of neuroimaging studies have provided insight into the neurobiological mechanisms of posttraumatic stress disorder (PSTD). In particular, molecular neuroimaging techniques have been employed...
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