- Excitotoxic Cell Death in Cultured Retinal Neurons
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Yoon YH, Shim MJ, Lee J
- KMID: 2123633
- J Korean Ophthalmol Soc.
- 1997 Nov;38(11):1987-1999.
We examined excitotoxicity, putatively a major mechanism of ischemic neuronal death, in primary rat retinal cultures. Retinal cultures were prepared from newborn rats (day 1 or 2). Exposure of these... -
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- Mechanism of Hypoxia-Induced Cytotoxicity in Cultured Rat Retinal Neurons
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Yoon YH, Lee J
- KMID: 2123632
- J Korean Ophthalmol Soc.
- 1997 Nov;38(11):1975-1986.
Retinal neurons are highly vulnerable to hypoxia/ischemia. Excitotoxicity and free radical injury have been proposed as the major mechanisms of ischemic retinal injury have been proposed as the major mechanisms... -
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- Colocalization of GABA and Glycine within the Neurons of the Rat Retina
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Son WH, Oh SJ, Kim IB, Chun MH, Jung JW
- KMID: 2224609
- Korean J Anat.
- 1997 Dec;30(6):695-704.
The role of GABA or glycine as an inhibitory neurotransmitter is well established, and GABAergic or glycinergic neurons appear to play an important role in the mammalian retinas. It has... -
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- NADPH Diaphorase Staining Retinal Cells in Streptozotocin-induced Diabetic Rat Retina
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Lee SJ, Huh K
- KMID: 2205362
- J Korean Ophthalmol Soc.
- 1998 Oct;39(10):2377-2384.
Nitric oxide(NO) is a free radical which serves a wide variety of functions on vascular tone, neurotransmission, immune cytotoxicity, and many others. Nitric oxide synthase(NOS) is the biosynthetic enzyme of... -
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- Neuronal Cell Death in Reina Ischemia Induced by Elevation of Intraocular Pressure
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Choi JS, Gwag BJ, Kim SJ, Chun MH, Joo CK
- KMID: 2205403
- J Korean Ophthalmol Soc.
- 1998 Nov;39(11):2701-2708.
This study was conducted to compare degeneration of retinal neurons in retina ischemia induced by sudden elevation of intraocular pressure(IOP)(Group A) with that by steady elevation of IOP(Group B). Adult... -
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- The Effects of N-Methyl_D-Aspartic Acid, and Antagonism by Kynurenic Acid on Neurons in the Cathish Retina
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Lee SJ, Jung CS, Bai SH
- KMID: 2205353
- J Korean Ophthalmol Soc.
- 1998 Oct;39(10):2303-2312.
To investigate the mechanism of the excitatory signal transmission, the effects of N-methyl-D-aspartate(NMDA, ionotropic glutamate agonist) and kynurenic acid(glutamate antagonist) on catfish retinal neurons were explored using conventional intracellular recording... -
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- Effects of the Center-Surround Light Stimuli on the Catfish Retianl Neurons
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Lee SJ, Han HK, Lee SY, Jung CS, Bai SH
- KMID: 2124085
- J Korean Ophthalmol Soc.
- 1998 Mar;39(3):509-520.
For the investigation of the receptive field of the retinal neurons, the spatial and temporal properties of horizontal cells and the center-surround antagonisms of bipolar cells and the third-order neurons... -
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- Expression of p53 in Retina Neuronal Cell Death Induced by Ischemia and Reperfusion
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Choi JS, Gwag BJ, Kim SJ, Chun MH, Joo CK
- KMID: 2205401
- J Korean Ophthalmol Soc.
- 1998 Nov;39(11):2679-2686.
In order to elucidate the mechanism of neuronal cell death induced by retina ischemia and reperfusion, we investigated expression of p53, Bcl-2, and ICE(interleukin converting enzyme) in retinal neuronal cell... -
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- Distribution of the Glycosaminoglycans in the Bruch`s Membrane and Sensory Retina : Histochemical Electromic roscopic Findings with Ruthenium Red
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Lee WK, Ko MK, Kim DS
- KMID: 2124304
- J Korean Ophthalmol Soc.
- 1999 Jul;40(7):1877-1883.
The distribution of glycosaminoglycans in Bruch`s membrane and sensory retina of human eye was evaluated with histochemical electron microscope using 0.05%ruthenium red (RR). Seven donated or enucleated eyeballs without chorioretinal... -
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- Unlocking the Neurogenic Potential of Mammalian Müller Glia
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Xia X, Ahmad I
- KMID: 2362510
- Int J Stem Cells.
- 2016 Nov;9(2):169-175.
- doi: 10.15283/ijsc16020
Müller glia (MG) are the primary support cells in the vertebrate retina, regulating homeostasis in one of the most metabolically active tissues. In lower vertebrates such as fish, they respond... -
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- Retinal Neuronal Cell Death and Expression of p53p and Bax Protein Following Optic Nerve Axotomy
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Choi JJ, Kim Yoon S, Joo CK
- KMID: 2108523
- J Korean Ophthalmol Soc.
- 1998 Aug;39(8):1779-1787.
This investigation were performed in order to study the mechanism of neuronal cell degeneration and mediated gene of retinal cell death in optic nerve transection model. The optic nerve was... -
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- Effects of Extracellular Chloride Ions on the Catfish Retinal Neurons
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Kim JM, Chang KY, Bai SH
- KMID: 2123572
- J Korean Ophthalmol Soc.
- 1996 Nov;37(11):1822-1831.
The catfish (Ictalurus punctatus) retinal neurons were investigated by using the intracellular recording techniques to analyze the function of the chloride ions in the light responses and the ionic mechanisms... -
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- Pathophysiology of Diabetic Retinopathy: The Old and the New
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Kusuhara S, Fukushima , Ogura S, Inoue N, Uemura A
- KMID: 2422781
- Diabetes Metab J.
- 2018 Oct;42(5):364-376.
- doi: 10.4093/dmj.2018.0182
Vision loss in diabetic retinopathy (DR) is ascribed primarily to retinal vascular abnormalities—including hyperpermeability, hypoperfusion, and neoangiogenesis—that eventually lead to anatomical and functional alterations in retinal neurons and glial cells.... -
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- Histochemical Electron Microscopic Findings of the Distribution of the Glycosaminoglycans of Cultured Sensory Retina
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Kim JS, Kwon JW, Ko MK
- KMID: 2125410
- J Korean Ophthalmol Soc.
- 2002 Jan;43(1):197-203.
PURPOSE: This study was performed to investigate the distribution of glycosaminiglycans by the activated retinal neuronal cell on the cultured retinal tissue. METHODS: The retinal tissue was obtained from the donor... -
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- Immunohistochemical localization of heme oxygenase isozymes in the aged rat retina
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Lee HY
- KMID: 1558433
- Korean J Anat.
- 2001 Apr;34(2):169-179.
Heme oxygenase (HO)-1 and -2 isozymes are important markers for the oxidative stress. We localized HO-1 and HO-2 immunoreactivities and assessed the effect of aging on distribution of HO in... -
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- Morphological and functional evaluation of an animal model for the retinal degeneration induced by N-methyl-N-nitrosourea
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Jeong E, Paik SS, Jung SW, Chun MH, Kim IB
- KMID: 1447445
- Anat Cell Biol.
- 2011 Dec;44(4):314-323.
- doi: 10.5115/acb.2011.44.4.314
The retinal degeneration (RD) is a general cause of blindness. To study its pathophysiology and evaluate the effects of new therapeutic agents before clinical trials, it is essential to establish... -
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- Ribbon Synapses Formed at the Axon of the Calbindin-Immunoreactive ON Cone Bipolar Cell in OFF Sublamina of the Inner Plexiform Layer in the Rabbit Retina
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Koo TH, Kim HL, Jeon JH, Jeong EJ, Chun MH, Moon JI, Kim IB
- KMID: 1449614
- Korean J Phys Anthropol.
- 2011 Dec;24(4):195-201.
Some retinal neurons, including intrinsically photosensitive retinal ganglion cells have their dendrites stratified in sublamina a of the inner plexiform (IPL), the OFF sublayer, but paradoxically show light-driven ON electrophysiological... -
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- Morphology and Distribution of Gap Junction in Horizontal Cells of the Rabbit Retina
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Cha J, Kim IB
- KMID: 2092951
- Korean J Anat.
- 2008 Dec;41(4):271-277.
Horizontal cells (HCs) of the mammalian retina are interneurons that provide negative feedback to photoreceptors in the outer plexiform layer (OPL) where the first synapse occurs and contribute to the... -
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- Gap Junction Contributions to the Goldfish Electroretinogram at the Photopic Illumination Level
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Kim DY, Jung CS
- KMID: 1768017
- Korean J Physiol Pharmacol.
- 2012 Jun;16(3):219-224.
- doi: 10.4196/kjpp.2012.16.3.219
Understanding how the b-wave of the electroretinogram (ERG) is generated by full-field light stimulation is still a challenge in visual neuroscience. To understand more about the origin of the b-wave,... -
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- Expression of Substance P in the Experimental Diabetic Rat Retina
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Lee SM, Park SJ, Kang TH, Chung JW, Chun MH, Oh SJ
- KMID: 1937827
- Korean J Anat.
- 2006 Apr;39(2):159-167.
Substance P (Sub P) being composed of 11 amino acids sequence is a kind of tachykinin family peptides. It has been known that this substance plays a role of neurotransmitter... -
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