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Updates on the Diagnosis and Treatment of Restless Legs Syndrome

Kang SG

Restless legs syndrome (RLS) is a neurological sleep disorder characterized by an urge to move the legs or arms and is associated with discomfort and paresthesia in the legs. RLS...
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Relationships between Symptom of Restless Legs Syndrome, Depression, Somatic Symptom and Activities of Daily Living among the Elderly

Moon SS, Suh YO, Lee KW

PURPOSE: The purpose of this study was to investigate relationships between the symptom of restless legs syndrome (RLS), somatic symptom, depression, and activities of daily living (ADL) among the elderly. METHODS:...
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Symptom Aggravation in Restless Legs Syndrome during Menstrual Cycle

Hwang S, Shin YW, Jung KY

OBJECTIVES: The purpose of this study is to confirm restless legs syndrome (RLS) symptom aggravation during menstrual period and verify factors related to symptom aggravation. METHODS: A total of 20 premenopausal female...
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Sleep, Sleep Disorders, and Sexual Dysfunction

Cho JW, Duffy JF

Good sleep is necessary for good health. Sleep health is increasingly recognized as important for physical and mental health by both the medical profession and the general public, and there...
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Sleep Disorders and Menopause

Lee J, Han Y, Cho HH, Kim MR

Sleep disorders are one of the main symptoms of menopause. Symptoms of sleep disorders that menopausal women complain about include falling asleep, frequent awakening and/or early morning awakening. There are...
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Restless Legs Syndrome in Parkinson's Disease Patients: Clinical Features Including Motor and Nonmotor Symptoms

You S, Jeon SM, Do SY, Cho YW

BACKGROUND AND PURPOSE: We investigated the frequency and clinical features of restless legs syndrome (RLS) in patients with Parkinson's disease (PD). METHODS: This study included 74 PD patients. RLS was diagnosed...
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Association between Restless Legs Syndrome Symptoms and Self-Reported Hypertension: a Nationwide Questionnaire Study in Korea

Sunwoo JS, Kim WJ, Chu MK, Yang KI

BACKGROUND: The association between restless legs syndrome (RLS) and hypertension remains controversial. We investigated the relationship between RLS and hypertension in a nationwide sample of the Korean adult population. METHODS: This...
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Restless Legs Syndrome in Pregnant Thai Women: Prevalence, Predictive Factors, and Natural Course

Panvatvanich S, Lolekha P

BACKGROUND AND PURPOSE: Restless legs syndrome (RLS) is a common sleep-related neurological disorder that affects the quality of sleep. This study aimed to estimate the prevalence, predictive factors, and natural...
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Relationship of Restless Legs Syndrome Symptom, Sleep Disturbance and Depression in Middle-aged Women

Suh YO, Moon SS, Lee KW

PURPOSE: The purpose of this study was to investigate relationships between the symptoms of Restless Legs Syndrome (RLS), sleep disturbance and depression among middle-aged women. METHODS: The study took a descriptive...
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Cardiac Activation Associated with Non-Periodic Leg Movements in Comparison to Periodic Leg Movements during Sleep in Patients with Restless Legs Syndrome and Healthy Subjects

Kim MJ, Cha KS, Kim TJ, Jun JS, Jung KY

OBJECTIVES: Periodic leg movements in sleep (PLMS) are associated with arousals and autonomic activation, which may contribute to higher cardiovascular disease risk in patients with restless legs syndrome (RLS). Non-periodic...
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Difference in Sleep Characteristics between Restless Leg Syndrome With and Without Periodic Limb Movement during Wakefulness

Shin YY, Byun JI, Shin WC

OBJECTIVES: Restless leg syndrome (RLS) is a common sensorimotor disorder and is frequently associated with periodic limb movement in sleep (PLMS). Also about one third of patient with RLS have...
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Relationship between Smoking and Sleep Disturbance

Bae S, Kim HS, Kang SG

Smoking is one of the most harmful causes of disease. Many previous researches have shown that cigarette smoking leads to cardiovascular, respiratory, oncologic, and cerebrovascular diseases. In addition to such...
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Clinical Predictors of Excessive Daytime Sleepiness in Patients with Parkinson's Disease

Junho BT, Kummer A, Cardoso F, Teixeira A, Rocha NP

BACKGROUND AND PURPOSE: Excessive daytime sleepiness (EDS) is a common complaint among patients with Parkinson's disease (PD). Several factors have been associated with EDS in PD, especially neuropsychiatric symptoms. This...
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Successful Management of Clozapine-induced Akathisia with Gabapentin Enacarbil: A Case Report

Takeshima , Ishikawa H, Kikuchi Y, Kanbayashi T, Shimizu T

The management of clozapine (CLZ)-induced adverse events affects patient prognoses. Akathisia is a relatively rare adverse event related to CLZ administration and thus the management of this syndrome is not...
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Higher Prevalence of Hypertension among Individuals with Restless Legs Syndrome: A Meta-Analysis

Hwang IC, Na KS, Lee YJ, Kang SG

OBJECTIVE: This study investigated the proposed association between restless legs syndrome (RLS) and the prevalence of hypertension. METHODS: A meta-analysis was conducted based on searches of the PUBMED, EMBASE, Cochrane Library,...
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Clinical Factors Related to the Response of IV Ferric Carboxymaltose Treatment in Patients with Restless Legs Syndrome

Park HR, Park HS, Choi SJ, Joo EY

OBJECTIVES: Significant benefit of intravenous ferric carboxymaltose (FCM) for restless legs syndrome (RLS) has been demonstrated. However, clinical indicators to expect treatment response of RLS are not clarified. The aim...
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Updates on the Treatment of Restless Legs Syndrome

Kang SG

Restless legs syndrome (RLS) is a sleep disorder characterized by an urge to move the legs or arms and uncomfortable paresthesia in the legs. Treatment of RLS can be various...
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Anaphylaxis to Intravenous Ferric Carboxymaltose

Kim KT, Jong-Ho B, Cho YW

The efficacy and the adverse effects of intravenous iron formulas have been well established. However, there are few reports of anaphylaxis of ferric carboxymaltose (FCM). A man received intravenous FCM...
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Symptom Persistence after Iron Normalization in Women with Restless Legs Syndrome

Bang YR, Jeon HJ, Park HY, Yoon IY

OBJECTIVE: The aim of this study was to determine the clinical course of restless legs syndrome (RLS) and potential risk factors for the persistence of RLS symptoms after iron normalization...
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Haplotype Association of the MAP2K5 Gene with Antipsychotics-Induced Symptoms of Restless Legs Syndrome among Patients with Schizophrenia

Kang SG, Lee YJ, Park YM, Kim L, Lee HJ

OBJECTIVE: Restless legs syndrome (RLS) is considered a genetic disease and, following a genome-wide association study conducted in 2007, the mitogen-activated protein kinase 5 (MAP2K5) gene has been regarded as...
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