J Korean Neurol Assoc.  2018 May;36(2):110-112. 10.17340/jkna.2018.2.11.

Anaphylaxis to Intravenous Ferric Carboxymaltose

Affiliations
  • 1Department of Neurology, Keimyung University Dongsan Medical Center, Daegu, Korea. neurocho@gmail.com

Abstract

The efficacy and the adverse effects of intravenous iron formulas have been well established. However, there are few reports of anaphylaxis of ferric carboxymaltose (FCM). A man received intravenous FCM for the treatment of restless legs syndrome. The FCM gave rise to angioedema, urticaria, chest tightness, sinus tachycardia, and hypotension. In the end, epinephrine and dexamethasone resolved the symptoms. The findings were consistent with anaphylactic hypersensitivity reaction from FCM. We need to be careful when we administer FCM in clinics.

Keyword

Iron; Ferric carboxymaltose; Anaphylaxis; Restless legs syndrome

MeSH Terms

Anaphylaxis*
Angioedema
Dexamethasone
Epinephrine
Hypersensitivity
Hypotension
Iron
Restless Legs Syndrome
Tachycardia, Sinus
Thorax
Urticaria
Dexamethasone
Epinephrine
Iron
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