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Possible Roles of UL112-113 Proteins in Human Cytomegalovirus DNA Replication

Kim YE, Ahn JH

DNA replication of human cytomegalovirus (HCMV) is a highly regulated process that requires specific interactions between cis-acting lytic origin of replication (oriLyt) and trans-acting viral proteins. Formation of the replication...
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Characterization of the Repeat Sequences of Varicella-Zoster Virus

Won YH, Kim JI, Kim YY, Lee CH

Varicella-zoster virus (VZV) is a causative agent for shingles and herpes zoster. The genomes of VZV contain five reiteration (R) sequences and an origin of replication (ORI) sequences composed of...
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HIV - 1 p24 Expression in BCG and the Immunogenicity of Recombinant BCG in Experimental Animals

Cho SH, Myoung HJ, Jeong HR, Bai GH, Kim SJ, Bae YS

  • KMID: 1548228
  • Korean J Immunol.
  • 1997 Jun;19(2):289-300.
HIV-1 p24 was cloned into multiple cloning site of pMV261, extrachromosomal expression vectors carrying BCG replication origin and BCG-specific heat-shock promoter, and then introduced into BCG and E. coli. Western...
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Construction of A Stable Full-Length cDNA Clone of Japanese Encephalitis Virus Strain SA14-14-2 Using Low Copy Number Plasmid

Min KI, Kim YM, Choo MS, Baek SY, Kim JO, Ryu SR, Min BS, Kim Y, Park MK, Byeon WH, Hur SJ

  • KMID: 1579128
  • J Bacteriol Virol.
  • 2004 Dec;34(4):339-353.
Recently the reverse genetics system contributed to the progresses in the investigation of positive-stranded RNA viruses. Here, we report the successful construction of a stable full-length infectious cDNA clone of...
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Glucose-dependent Insulin Secretion from Genetically Engineered K-cells Using EBV-based Episomal Vector

Kim JH, Moon SD, Ko SH, Ahn YB, Song KH, Lim HS, Lee SK, Yoo SJ, Son HS, Yoon KH, Cha BY, Son HY, Kim SJ, Han JH

BACKGROUND: Type 1 diabetes mellitus is an autoimmune disease resulting in destruction of the pancreatic beta cells. Insulin gene therapy for these patients has been vigorously researched. The strategy for...
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