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CD44 Disruption Attenuates Murine Hepatic Ischemia/Reperfusion Injury

Kim MS, Lee KH, Lee WM, Jun JH, Kim DH

Neutrophil adhesion and migration are critical in hepatic ischemia/reperfusion (I/R) injury. Despite very strong preclinical data, recent clinical trials failed to show a protective effect of anti-adhesion therapy in reperfusion...
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Bioelectrical Impedance May Predict Cell Viability During Ischemia and Reperfusion in Rat Liver

Cui ML, Ahn HS, Kim JY, Shin HJ, Lee DS, Kim HJ, Yun SS

Ischemia and reperfusion (I/R) injury is a major cause of hepatic failure after liver surgery, but no method could monitor or predict it real-time during surgery. We measured bioelectrical impedance...
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Involvement of GADD153 and cardiac ankyrin repeat protein in cardiac ischemia-reperfusion injury

Lee MJ, Kwak YK, You KR, Lee BH, Kim DG

Oxidative stress is critical for causing cardiac injuries during ischemia-reperfusion (IR), yet the molecular mechanism for this remains unclear. In the present study, we observe that hypoxia and reoxygenation, a...
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Activated Protein C Protects Myocardium Via Activation of Anti-apoptotic Pathways of Survival in Ischemia-reperfused Rat Heart

Ding JW, Tong XH, Yang J, Liu ZQ, Zhang Y, Yang J, Li S, Li L

Activated protein C (APC) is known to be beneficial on ischemia reperfusion injury in myocardium. However, the protection mechanism of APC is not fully understood. The purpose of this study...
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