- Effect of Stem Cells and Gene Transfected Stem Cells Therapy on the Pancreas of Experimentally Induced Type 1 Diabetes
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Zickri MB, Aboul-Fotouh GI, Omar AI, El-Shafei , Reda AM
- KMID: 2429553
- Int J Stem Cells.
- 2018 Nov;11(2):205-215.
- doi: 10.15283/ijsc18002
BACKGROUND AND OBJECTIVES: Insulin secretion entirely depends on Ca²⺠influx and sequestration into endoplasmic reticulum (ER) of β-cells, performed by Sarco-ER Ca²âº-ATPase 2b (SERCA2b). In diabetes, SERCA2b is decreased in... -
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- Effect of Stem Cells, Ascorbic Acid and SERCA1a Gene Transfected Stem Cells in Experimentally Induced Type I Diabetic Myopathy
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Zickri MB, Sadek EM, Fares AE, Heteba NG, Reda AM
- KMID: 2500575
- Int J Stem Cells.
- 2020 Mar;13(1):163-175.
- doi: 10.15283/ijsc18066
Background and Objectives: Sarco/endoplasmic reticulum Ca2＋-ATPase (SERCA) inhibition was proved in streptozotocin (STZ)-diabetic rats. The present study aimed at investigating and comparing the therapeutic effect of bone marrow mesenchymal stem... -
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