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Wnt5a stimulates chemotactic migration and chemokine production in human neutrophils

Jung YS, Lee HY, Kim SD, Park JS, Kim JK, Suh PG, Bae YS

  • KMID: 2154246
  • Exp Mol Med.
  • 2013 Jun;45(6):e27.
Wnt5a is a ligand that activates the noncanonical Wnt signaling pathways (beta-catenin-independent pathways). Human neutrophils expressed several Wnt5a receptors, such as Frizzled 2, 5 and 8. Stimulation of human neutrophils...
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Disturbed Osteoblastic Differentiation of Fibrous Hamartoma Cell from Congenital Pseudarthrosis of the Tibia Associated with Neurofibromatosis Type I

Lee DY, Cho TJ, Lee HR, Lee K, Moon HJ, Park MS, Yoo WJ, Chung CY, Choi IH

BACKGROUND: Fibrous hamartoma is the key pathology of congenital pseudarthrosis of the tibia (CPT), which was shown to have low osteogenicity and high osteoclastogenicity. This study further investigated the mechanism...
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