- Role of Clusterin and Tumor Necrosis Factor Receptors on the Apoptosis of Prostate Cancer Cells
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Joo KJ
- KMID: 2298625
- Korean J Androl.
- 2011 Apr;29(1):43-52.
- doi: 10.5534/kja.2011.29.1.43
PURPOSE: In prostate cancer, the anti-apoptotic mechanism of sulfated glycoprotein-2 (clusterin) against tumor necrosis factor-alpha (TNF-alpha) receptors and the action of type 2 TNF-alpha receptor (TNFR2) were investigated. MATERIALS AND METHODS:... -
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- Etanercept in the Treatment of Generalized Annular Pustular Psoriasis
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Lo Schiavo A, Brancaccio G, Puca RV, Caccavale
- KMID: 2434698
- Ann Dermatol.
- 2012 May;24(2):233-234.
No abstract available. -
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- TNFalpha and TNFR2 Immunohistochemistry During Ovarian Follicular Development and Atresia in the Rat
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Han SR, Son SK, Yang YS, Kim WS
- KMID: 2224491
- Korean J Anat.
- 2005 Dec;38(6):553-559.
Tumor necrosis factor alpha (TNFalpha) is an intraovarian cytokine that may play a role in ovarian development and function. Identification of ovarian TNFalpha receptors provides support for establishing a role... -
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- A Case of Tumor Necrosis Factor-alpha Inhibitors-induced Pustular Psoriasis
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Park JJ, Lee SC
- KMID: 2265398
- Ann Dermatol.
- 2010 May;22(2):212-215.
- doi: 10.5021/ad.2010.22.2.212
Anti-tumor necrosis factor (TNF)-alpha agents promise better disease control for the treatment of ankylosing spondylitis resistant to classical disease-modifying treatments. Etanercept, a recombinant human TNF receptor fusion protein, is used... -
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- Tumor Necrosis Factor and Regulatory T Cells
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Jung MK, Lee JS, Kwak JE, Shin EC
- KMID: 2431628
- Yonsei Med J.
- 2019 Feb;60(2):126-131.
- doi: 10.3349/ymj.2019.60.2.126
CD4âºCD25âºFoxP3⺠regulatory T (Treg) cells play major roles in the maintenance of immune homeostasis. In this review, we comprehensively describe the relationship between tumor necrosis factor (TNF) and Treg cells,... -
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- A Case of Psoriasiform Eruption Triggered by Tumor Necrosis Factor-alpha Antagonist Therapy
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Choi YJ, Kim DS, Park JM, Oh SH, Park YK, Lee JH
- KMID: 2248315
- Korean J Dermatol.
- 2008 May;46(5):721-723.
Tumor necrosis factor-alpha antagonists include monoclonal antibodies, infliximab, adalimumab, etanercept and golimumab. Clinical trials of these agents have shown that they are remarkably effective for psoriasis, but cutaneous adverse reactions... -
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- A Case of Refractory SAPHO Syndrome Treated with Etanercept
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Kim YJ, Bae SI, Choi SJ, Lee YH, Ji JD, Song GG
- KMID: 2223121
- J Rheum Dis.
- 2012 Feb;19(1):51-54.
- doi: 10.4078/jrd.2012.19.1.51
SAPHO syndrome, which has different skin changes and osteoarticular inflammation, is an acronym that stands for synovitis, acne, pustulosis, hyperostosis, and osteitis. Treatment of SAPHO syndrome includes non-steroidal anti-inflammatory drugs... -
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- A Case of Development of Sarcoidosis During Tumor Necrosis Factor-alpha Antagonist Therapy
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Park SY, Kim EK, Hwang DW, Lee KW, Paik SS, Jung KH, Kim TH
- KMID: 2223181
- J Rheum Dis.
- 2011 Mar;18(1):41-45.
- doi: 10.4078/jrd.2011.18.1.41
Etanercept is a soluble receptor fusion protein that inhibits tumor necrosis factor-alpha(TNF-alpha). The receptor is used widely in the treatment of ankylosing spondylitis, rheumatoid arthritis, sarcoidosis and other indications. For... -
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- The Roles of CD137 Signaling in Atherosclerosis
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Jung IH, Oh GT
- KMID: 2355448
- Korean Circ J.
- 2016 Nov;46(6):753-761.
- doi: 10.4070/kcj.2016.46.6.753
The tumor necrosis factor receptor superfamily (TNFRSF), which includes CD40, LIGHT, and OX40, plays important roles in the initiation and progression of cardiovascular diseases, involving atherosclerosis. CD137, a member of... -
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- Predictive Value of Conjointly Examined IL-1ra, TNF-R I, TNF-R II, and RANTES in Patients with Primary Glomerulonephritis
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Zwiech R
- KMID: 1429194
- J Korean Med Sci.
- 2013 Feb;28(2):261-267.
- doi: 10.3346/jkms.2013.28.2.261
Interleukin-1 receptor antagonist (IL-1ra), tumor necrosis factor soluble receptors (sTNF-R) type I and II, and regulated upon activation, normal T-cell expressed and secreted (RANTES) play an important role in the... -
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- A Case of Acute Myeloid Leukemia after Adalimumab Treatment in Psoriatic Arthritis
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Min HK, Lee JH, Lee HM, Koh E, Heo JY, Min JK, Park SH
- KMID: 2223106
- J Rheum Dis.
- 2012 Apr;19(2):91-94.
- doi: 10.4078/jrd.2012.19.2.91
Hematologic malignancies and lymphoproliferative disorders have been reported after using tumor necrosis factor-alpha inhibitor in patients suffering from spondyloarthropathy. Previously reported cases were treated by using infliximab and etanercept. Usually,... -
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- New drugs for Rheumatoid arthritis
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Seo YI
- KMID: 2257380
- Korean J Med.
- 2009 Jan;76(1):12-17.
Since the late 1990s, based on scientific advancement and biotechnological improvement, many effective drugs such as leflunomide and biologic agents for rheumatoid arthritis (RA) have been developed. These include TNF-alpha... -
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- Differential Signaling via Tumor Necrosis Factor-Associated Factors (TRAFs) by CD27 and CD40 in Mouse B Cells
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Woo SY, Park HK, Bishop GA
- KMID: 2167975
- Immune Netw.
- 2004 Sep;4(3):143-154.
- doi: 10.4110/in.2004.4.3.143
BACKGROUND: CD27 is recently known as a memory B cell marker and is mainly expressed in activated T cells, some B cell population and NK cells. CD27 is a member... -
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- A Case of Macropharge Activation Syndrome Successfully Treated with Combination Therapy Including Etanercept
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Sim YS, Kim HS, Kim KN
- KMID: 2223076
- J Rheum Dis.
- 2012 Aug;19(4):225-229.
- doi: 10.4078/jrd.2012.19.4.225
Macrophage activation syndrome (MAS) is a severe, potentially life-threatening complication of childhood systemic inflammatory disorder, primarily systemic onset juvenile rheumatoid arthritis (SoJRA). It is characterized by pancytopenia, liver insufficiency, coagulopathy,... -
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- Interstitial Lung Disease That Occurred during Treatment with Etanercept (Enbrel(R)) of Psoriasis Patients
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Park SB, Kim HR, Im M, Lee Y, Seo YJ, Lee JH
- KMID: 2246592
- Korean J Dermatol.
- 2013 Sep;51(9):709-712.
Etanercept is widely used to treat autoimmune rheumatic, digestive, and dermatologic diseases such as psoriasis. It acts as a competitive inhibitor of tumor necrosis factor (TNF)-alpha and has acceptable safety... -
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- The Incidence of Serious Infection among Rheumatoid Arthritis Patients Exposed to Tumor Necrosis Factor Antagonists
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Kim HO, Kang KY, Ju JH, Kim HY, Park SH
- KMID: 2334912
- J Korean Rheum Assoc.
- 2010 Sep;17(3):246-253.
OBJECTIVE: We wanted to investigate the incidence of serious infections among the rheumatoid arthritis (RA) patients who were treated with tumor necrosis factor alpha (TNF-alpha) antagonists. METHODS: We enrolled the 175... -
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- Screening of Genes Regulating TNF-alpha-mediated Synovial Hyperplasia in Rheumatoid Arthritis
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Huh SJ, Youn J
- KMID: 1917148
- Korean J Phys Anthropol.
- 2003 Jun;16(2):89-95.
Chronic rheumatoid arthritis (RA) is characterized by the hyperplasia of synovial tissue, which results from the combined influence of the proliferation and antiapoptosis of the synovial cells. In this study,... -
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- The Expression and Function of the Tumor Necrosis Factor Receptor I (TNFRI), TNFRII, and X-Linked Inhibitor of Apoptosis Genes after Spinal Cord Injury in Rats
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Yang JY, Lee JK, Kim KT, Lee HH, Byun BN, Ahn SH
- KMID: 2003187
- J Korean Soc Spine Surg.
- 2004 Mar;11(1):14-23.
- doi: 10.4184/jkss.2004.11.1.14
STUDY DESIGN AND OBJECTIVE: Tumor necrosis factor-alpha(TNF-alpha), a key inflammatory mediator, has been demonstrated in spinal cord injury (SCI). However, the expression of TNF receptors following SCI remains to be... -
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- Cytokine profiles in synovial fluid of rheumatoid arthritis
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Jeon CH, Kim JH, Park JH, Ahn KS, Kim HJ, Kim EH, Ahn JK, Cha HS, Koh EM
- KMID: 2252799
- Korean J Med.
- 2003 May;64(5):576-587.
BACKGROUND: The assay of cytokines and their soluble receptors in the synovial fluid of inflammatory arthropathy may be useful in studying pathogenetic and immunoregulatory mechanisms of different arthritis. The aim... -
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- The Effect of Tumor Necrosis Factor-Alpha Inhibitors on Uveitis in Patients with Ankylosing Spondylitis
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Lee S, Park YJ, Lee JY
- KMID: 2461174
- J Korean Med Sci.
- 2019 Nov;34(42):e278.
- doi: 10.3346/jkms.2019.34.e278
BACKGROUND: Tumor necrosis factor-alpha (TNF-α) inhibitors (TNFis), which are the main treatment for ankylosing spondylitis (AS), have been reported not only to reduce the incidence of anterior uveitis (AU) but... -
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