- Bisphenols and Thyroid Hormone
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Kim MJ, Park YJ
- KMID: 2466252
- Endocrinol Metab.
- 2019 Dec;34(4):340-348.
- doi: 10.3803/EnM.2019.34.4.340
In recent decades, attention has been directed toward the effects of bisphenol A (BPA) on human health. BPA has estrogenic activity and is regarded as a representative endocrine disruptor. In... -
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- A Case of Resistance Syndrome to Thyroid Hormone Associated with Mutation (G345D) in the Thyroid Hormone Receptor Beta Gene
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Park TJ, Kang JK, Seo KW, Kim HJ, Chung YS, Lee KW, Jeong SY, Kim HJ, Kim DJ
- KMID: 2063538
- J Korean Endocr Soc.
- 2007 Aug;22(4):277-281.
- doi: 10.3803/jkes.2007.22.4.277
Resistance syndrome to thyroid hormone (RTH) is a rare autosomal dominant disease that is characterized by decreased tissue responsiveness to thyroid hormone, and it is mainly due to mutations of... -
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- CCAAT-binding Transcription Factor(CTF) Proteins Required for the Transcriptional Stimulation by Thyroid Hormone in GH4C1 Cells
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Park HY, Hong YS
- KMID: 2078825
- Ewha Med J.
- 1995 Dec;18(4):309-313.
- doi: 10.12771/emj.1995.18.4.309
CAAT-binding transcription factor(CTF) proteins are implicated in the expression of multipleforms and are probably identical to nuclear facfor-1(NF-1). In herpes simplex virus thymidinekinase gene, CTF is required not only to... -
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- Case of Thyroid Hormone Resistance Syndrome with a Mutation in the Thyroid Hormone Receptor Beta Gene
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Lim SK, Kim SY, Kang JG, Kim CS, Ihm SH, Yoo HJ, Lee SJ
- KMID: 2258892
- Korean J Med.
- 2011 Jun;80(Suppl 2):S220-S226.
In thyroid hormone resistance syndrome (THR) TSH levels are normal or elevated despite thyroid hormone levels being elevated. THR is distinguished from TSH-producing pituitary adenoma by TRH stimulation and alpha-subunit... -
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- Thyroid Hormone Resistance in a Preterm Infant with a Novel THRB Mutation
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Bae JY, Kim DY, Kwon YD, Song YH, Lim HH, Park HD, Lim JW
- KMID: 2451609
- Neonatal Med.
- 2019 May;26(2):111-116.
- doi: 10.5385/nm.2019.26.2.111
Resistance to thyroid hormone (RTH) is a condition caused by a mutation in the thyroid hormone receptor gene. It is rarely reported in individuals with no family history of RTH... -
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- A Case of Syndrome of Resistance to Thyroid Hormone Associated with Mutation(M313T) in Thyroid Hormone Receptor Beta Gene
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Hwang JK, Kim KW, Kim TY, Kim SW, Park YJ, Park DJ, Kim SY, Lee HK, Cho BY
- KMID: 2331176
- J Korean Soc Endocrinol.
- 2003 Apr;18(2):206-213.
Syndrome of resistance to thyroid hormone(RTH) is inherited by an autosomal dominant trait, and characterized by elevated thyroid hormone levels with reduced responsiveness of the pituitary and peripheral tissues to... -
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- Effect of Thyroid Hormone to the Expression of ATP-binding Cassette Transporter ABCG5
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Ahn HY, Jang JM, Lee KJ, Kim SH, Kim KW, Park DJ, Jang HC, Park YJ
- KMID: 2012970
- J Korean Thyroid Assoc.
- 2011 May;4(1):39-46.
BACKGROUND AND OBJECTIVES: Excretion of bile acid and free cholesterol of bile was important to maintain cholesterol homeostasis. ATP-binding cassette transporter G5 (ABCG5) and G8 (ABCG8) promoted biliary cholesterol excretion.... -
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- Transcriptional Regulation of Pyruvate Dehydrogenase Kinase
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Jeong JY, Jeoung NH, Park KG, Lee IK
- KMID: 2174390
- Diabetes Metab J.
- 2012 Oct;36(5):328-335.
- doi: 10.4093/dmj.2012.36.5.328
The pyruvate dehydrogenase complex (PDC) activity is crucial to maintains blood glucose and ATP levels, which largely depends on the phosphorylation status by pyruvate dehydrogenase kinase (PDK) isoenzymes. Although it... -
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- Regulation of Steroid Thyroid Hormone Receptor 3 (TR3) mRNA Expression by Luteinizing Hormone in Human Early Luteinized Granulosa Cells
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Park HJ, Kim BR, Chun SY, Lee YI
- KMID: 2128995
- Korean J Obstet Gynecol.
- 2002 Oct;45(10):1736-1745.
OBJECTIVE: The present study examined the gonadotropin regulation of TR3 gene expression by luteinizing hormone (LH) in cultured human luteinized granulosa cells. METHODS: TR3 mRNA levels were detected by competitive... -
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- Thyroid Hormone Regulates the mRNA Expression of Small Heterodimer Partner through Liver Receptor Homolog-1
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Ahn HY, Kim HH, Kim YA, Kim M, Ohn JH, Chung SS, Lee YK, Park DJ, Park KS, Moore DD, Park YJ
- KMID: 2169669
- Endocrinol Metab.
- 2015 Dec;30(4):584-592.
- doi: 10.3803/EnM.2015.30.4.584
BACKGROUND: Expression of hepatic cholesterol 7alpha-hydroxylase (CYP7A1) is negatively regulated by orphan nuclear receptor small heterodimer partner (SHP). In this study, we aimed to find whether thyroid hormone regulates SHP... -
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- Thyroid Hormone Receptor Dynamics in Thyroid Hormone Response Elements of the Human Type 1 Iodothyronine Deiodinase Gene
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Lee SJ, Park CY, Jeong IK, Hong EG, Choi CS, Kim HK, Kim DM, Yoo JM, Ihm SH, Choi MG, Yoo HJ, Park SW, Larsen PR
- KMID: 2200307
- J Korean Soc Endocrinol.
- 2003 Jun;18(3):283-295.
BACKGROUND: Type 1 iodothyronine deiodinase (D1), the product of the hdio1 gene, is involved in thyroid hormone activation by the deiodination of thyroxine (T4) to form 3, 5, 3'-triiodothyronine (T3).... -
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- The Effect of T3 on Thyroid Hormone Receptor Dynamics in Thyroid Hormone Response Element of Chicken Lysozyme Silencer
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Lee SJ, Park CY, Jeong IK, Hong EG, Choi CS, Kim HK, Kim DM, Yoo JM, Ihm SH, Choi MG, Yoo HJ, Park SW, Larsen PR
- KMID: 2200383
- J Korean Soc Endocrinol.
- 2003 Aug;18(4):379-391.
BACKGROUND: The regulation of gene transcription can be controlled by both positive (enhancer) and negative (silencer) regulatory sequences. Several enhancer and silencer elements have been described in the 5' region... -
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- The functional role of the CARM1-SNF5 complex and its associated HMT activity in transcriptional activation by thyroid hormone receptor
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Choi HK, Choi KC, Oh SY, Kang HB, Lee YH, Haam S, Ahn YH, Kim KS, Kim K, Yoon HG
- KMID: 756078
- Exp Mol Med.
- 2007 Aug;39(4):544-555.
We have investigated the function and mechanisms of the CARM1-SNF5 complex in T3-dependent transcriptional activation. Using specific small interfering RNAs (siRNA) to knock down coactivators in HeLa alpha2 cells, we... -
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