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Protease from Airborn Fungi Induce Activation of Nasal Epithelial Cells

Shin SH, Park GU, Jeon CH

  • KMID: 2037116
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Feb;48(2):189-194.
BACKGROUND AND OBJECTIVES: The nasal epithelium is the first barrier encountered by airborne allergens and an active participant in airway inflammation. Fungi have been increasingly recognized as important pathogens in...
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Characterization of the distinct mechanism of agonist-induced canine platelet activation

Chaudhary , Kim S

Platelet activation has a major role in hemostasis and thrombosis. Various agonists including adenosine diphosphate (ADP) and thrombin interact with G protein-coupled receptors (GPCRs) which transduce signals through various G...
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Inhibition of Fungi-Induced Nasal Polyp Epithelial Cells Activation by Corticosteroids

Shin SH, Ye MK

  • KMID: 2131870
  • J Rhinol.
  • 2006 May;13(1):32-36.
BACKGROUND AND OBJECTIVES: Airway epithelial cells contribute to the pathogenesis of air disease by their interaction with inhalant pathogenic extracts. Airborne fungi interact with nasal epithelial cell and enhance the...
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The Role of Visceral Hypersensitivity in Irritable Bowel Syndrome: Pharmacological Targets and Novel Treatments

Farzaei MH, Bahramsoltani R, Abdollahi , Rahimi R

  • KMID: 2433449
  • J Neurogastroenterol Motil.
  • 2016 Oct;22(4):558-574.
  • doi: 10.5056/jnm16001
Irritable bowel syndrome (IBS) is the most common disorder referred to gastroenterologists and is characterized by altered bowel habits, abdominal pain, and bloating. Visceral hypersensitivity (VH) is a multifactorial process...
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Protease-Activated Receptors 2-Antagonist Suppresses Asthma by Inhibiting Reactive Oxygen Species-Thymic Stromal Lymphopoietin Inflammation and Epithelial Tight Junction Degradation

Kim HJ, Lee SH, Jeong S, Hong SJ

PURPOSE: Protease-activated receptor 2 (PAR2) reportedly triggers the immune response in allergic asthma. We aimed to investigate the mechanism on allergic inflammation mediated by PAR2. METHODS: Human lung epithelial cells (A549...
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