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Vasoactive Intestinal Peptide/Pituitary Adenylate Cyclase Activating Peptide Receptor Subtypes in Neuroblastoma, Stomach Cancer

Park SK, Park SJ, Kim HM, Jeong JY, Hur MK

  • KMID: 2278217
  • Korean J Pediatr Hematol Oncol.
  • 2001 Apr;8(1):51-57.
PURPOSE: We analyzed the expression of vasoactive intestinal peptide (VIP), pituitary adenylate cyclase activating peptide (PACAP), VIP receptor 1 (VIPR1), VIP receptor 2 (VIPR 2) and PACAP receptor (PACAPR) genes...
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Differential Regulation of Atrial Natriuretic Peptide in Clipped and Contralateral Kidneys in Two-Kidney, One Clip Hypertension

Kim SW, Lee JU, Oh YW, Li YS, Kim NH, Choi KC

  • KMID: 1889322
  • Korean J Nephrol.
  • 2002 Sep;21(5):728-733.
BACKGROUND: The present study was aimed to determine the pathophysiological implications of local atrial natriuretic peptide (ANP) system in the kidney in two- kidney, one clip (2K1C) hypertension. METHODS: Rats...
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Polymorphism of M341I in the Type A Human Natriuretic Peptide Receptor Gene in Essential Hypertension in Korea

Cho SE, Hong KS, Kim YD

OBJECTIVES: There are 3 subtypes of natriuretic peptide (NP) receptors: type A natriuretic peptide receptor (NPRA), NPRB, and NPRC. The NPRA gene polymorphism, consisting of substition of methionine (ATG) to...
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Regulation of Natriuretic Peptide Family mRNA Induced by Head-down Suspension in Rats

Bae JH

  • KMID: 2298443
  • Korean J Aerosp Environ Med.
  • 2004 Jun;14(2):51-56.
BACKGROUND: Head-down suspension (HDS) of rats has been used as a model for the simulation of a microgravity environment. Natriuretic peptide family including atrial natriuretic peptide (ANP), brain natriuretic peptide...
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Lu-177-Based Peptide Receptor Radionuclide Therapy for Advanced Neuroendocrine Tumors

Kim K, Kim SJ

Peptide receptor radionuclide therapy (PRRT) is a systemic cytotoxic radiation therapy using a compound of β-emitting radionuclide chelated to a peptide for the treatment of tumor with overexpressed specific cell...
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Changes in Renal Expression of Natriuretic Peptides and Their Receptors mRNA Induced by Head-down Suspension in Rats

Bae JH, Hwang JS

  • KMID: 1517671
  • Korean J Aerosp Environ Med.
  • 2003 Dec;13(4):184-189.
BACKGROUND: Head-down suspension (HDS) of rats has been used as a model for the simulation of a microgravity environment. Atrial natriuretic peptide (ANP), C-type natriuretic peptides (CNP) and their receptors...
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Expression of C-type Natriuretic Peptide and Natriuretic Peptide Receptors in the Mouse Submandibular Glands Following Embryonic Development, Postnatal Differentiation and Aging

Bok SM, Kim TH, Park KR, Cho ES

  • KMID: 1564369
  • Korean J Anat.
  • 2005 Aug;38(4):325-336.
C-type natriuretic peptide (CNP), a member of natriuretic peptide family, is mainly synthesized in the endothelium and central nervous system. But CNP is also involved in the growth and differentiation...
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Atrial Natriuretic Peptide System in Eyes

Kim H, Kim B, Kim SZ, Cho KW, Kim SH

  • KMID: 2147613
  • J Korean Ophthalmol Soc.
  • 1999 May;40(5):1184-1194.
Atrial natriuretic peptide(ANP), a peptide hormone synthesized mainly in the cardiac atrium, has an important physiological role on the regulation of body fluid and electrolyte balance. Extraatrial ANP system has...
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Optimal Treatment of Advanced Pancreatic Neuroendocrine Tumor

Kim YS, Cho JH

Pancreatic neuroendocrine tumors (pNETs) are diverse diseases with different prognosis. Among available various therapeutic options, curative resection should be considered for localized tumors and in some selected cases of metastatic...
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Studies of G Protein Activation of Orphanin FQ in the Cerebrum, Thalamus and Spinal Cord of Monkeys

Lee H, Han JI

BACKGROUND: The aim of this in vitro study was to investigate [35S]GTP gamma S binding stimulated activation by orphanin FQ in monkey cerebral, thalamic, and spinal membranes. METHODS: A rhesus monkey...
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Current Status of Theranostics in Jordan

Al-Ibraheem A, Mohamedkhair A

Exploring the unknown is one of the key factors that lead to great discoveries in mankind history.With the advances in medicine and the development of new approaches towards patient care,...
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C-Type Natriuretic Peptide/Natriuretic Peptide Receptor 2 Is Involved in Cell Proliferation and Testosterone Production in Mouse Leydig Cells

Yang L, Lei L, Zhao Q, Gong Y, Guan G, Huang S

PURPOSE: This study investigated the role of natriuretic peptide receptor 2 (NPR2) on cell proliferation and testosterone secretion in mouse Leydig cells. MATERIALS AND METHODS: Mouse testis of different postnatal stages...
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Relaxin Receptor RXFP1 and RXFP2 Expression in Ligament, Tendon, and Shoulder Joint Capsule of Rats

Kim JH, Lee SK, Lee SK, Kim JH, Fredericson M

Numerous musculoskeletal disorders are caused by thickened ligament, tendon stiffness, or fibrosis of joint capsule. Relaxin, a peptide hormone, can exert collagenolytic effect on ligamentous and fibrotic tissues. We hypothesized...
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The Emergence of Theranostics in the Philippines: Overcoming Challenges and Bringing Hope

Bautista P

Medical managements are becoming personalized while diseases are being understood at the molecular level. Nuclear medicine is one of the fields actively contributing to this development. In particular, theranostics, a...
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Peptide Receptor Radionuclide Therapy and the Treatment of Gastroentero-pancreatic Neuroendocrine Tumors: Current Findings and Future Perspectives

Hirmas N, Jadaan R, Al-Ibraheem A

PURPOSE AND METHODS: Patients with inoperable andmetastasized neuroendocrine tumors (NETs), particularly those with grades 1 and 2, usually receive treatment with somatostatin analogues (SSAs). Peptide receptor radionuclide therapy (PRRT) has...
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The effect of remifentanil infusion on coughing during emergence from general anesthesia with desflurane

Cho HR, Kim HK, Baek SH, Jung KY

BACKGROUND: Coughing during emergence from general anesthesia is a common clinical problem and results in a number of undesirable side effects. Remifentanil stimulate micron-opioid peptide receptor known to be related...
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Neuroendocrine Tumors

Park YS

  • KMID: 2267784
  • Korean J Med.
  • 2013 Oct;85(4):354-356.
Neuroendocrine tumors (NETs) are rare. However, several data showed the incidence is increased in the past 30 years. NETs can be both functional and non-functional, and may be undetected for...
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Therapeutic radionuclides

Choi SJ, Hong YD, Lee SY

  • KMID: 2313014
  • Nucl Med Mol Imaging.
  • 2006 Apr;40(2):58-65.
Since the development of sophisticated molecular carriers such as octereotides for peptide receptor targeting and monoclonal antibodies against various antigens associated with specific tumor types, radionuclide therapy (RNT) employing open...
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Primary hepatic neuroendocrine tumours of liver- a rarity: Single centre analysis of 13 patients

Parray A, Patkar S, Goel M

BACKGROUNDS/AIMS: Primary hepatic neuroendocrine tumours (PHNETs) are a rarity and this rarity imparts management complexities. METHODS: A retrospective analysis of prospectively maintained liver database from 2009 to 2018 was performed and...
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Current Status and Growth of Nuclear Theranostics in Singapore

Huang HL, Tong AK, Thang SP, Yan SX, Lam WW, Loke KS, Tang CY, Cheng LT, Ooi GS, Low HC, Magsombol , Tham WY, Goh CX, Tan CJ, Khor YM, Zaheer S, Bharadwaj , Xie W, Ng DC

The concept of theranostics, where individual patient-level biological information is used to choose the optimal therapy for that individual, has become more popular in the modern era of ‘personalised’ medicine....
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