- The effects of nalbuphine and fentanyl on experimental spinal cord injuries
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Lee WH
- KMID: 1752552
- Korean J Anesthesiol.
- 1994 May;27(5):428-448.
- doi: 10.4097/kjae.1994.27.5.428
Opiate receptor agonists (especially dynorphin - a kappa receptor agonist) have found to increase in the injuried segment of spinal cord. It is known to cause spinal cord damage when... -
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- Mu-Opioid Receptor Polymorphisms and Breast Cancer in a Korean Female Adult Population: A Retrospective Study
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Oh CS, Lee SH, Yoo YB, Yang JH, Kim SH
- KMID: 2308973
- J Breast Cancer.
- 2016 Jun;19(2):206-209.
- doi: 10.4048/jbc.2016.19.2.206
Distribution of A118G single nucleotide polymorphism (SNP) in the mu-opioid receptor 1 gene (OPRM1) differs with ethnicity. We assessed the distribution of this SNP in Korean women with breast cancer... -
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- Can oliceridine (TRV130), an ideal novel µ receptor G protein pathway selective (µ-GPS) modulator, provide analgesia without opioid-related adverse reactions?
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Ok HG, Kim SY, Lee SJ, Kim TK, Huh BK, Kim KH
- KMID: 2410828
- Korean J Pain.
- 2018 Apr;31(2):73-79.
- doi: 10.3344/kjp.2018.31.2.73
All drugs have both favorable therapeutic and untoward adverse effects. Conventional opioid analgesics possess both analgesia and adverse reactions, such as nausea, vomiting, and respiratory depression. The opioid ligand binds... -
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- The Effects of Peripheral mu and kappa Opioid Receptor Agonists on the Thermal Injury Induced Hyperalgesia in the Rat
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Chun YS, Jun JH, Shim JC, Kim KS, Suh JK, Yoo HK, Seung IS
- KMID: 1936000
- Korean J Anesthesiol.
- 2003 Feb;44(2):247-254.
- doi: 10.4097/kjae.2003.44.2.247
BACKGROUND: Previous reports have described that the local administration of opioid receptor agonist can attenuate the nociceptive responses induced by a variety of inflammatory states. This study evaluated the effects... -
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- Comparison of Blood Pressure and Heart Rate in Pediatric Tonsillectomy under Propofol-Remifentanil Anesthesia and Desflurane-N2O Anesthesia
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Lee DH, Kim DY, Park SW, Shin OY
- KMID: 1917406
- Anesth Pain Med.
- 2007 Apr;2(2):74-77.
BACKGROUND: Remifentanil is an ultra-short-acting mu opioid receptor agonist. However, there are few reports of its use in children. Therefore, this study compared propofol-remifentanil anesthesia (PR) with a desflurane-N2O anesthesia... -
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- The Effect of Morphine on REST Expression in Human Neuroblastoma NMB Cells
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Kim DK, Kim CS, Kim HJ, Kook JK, Kim SH, Lee BH, Lee YH, Mo SY, Loh HH
- KMID: 1457120
- Int J Oral Biol.
- 2010 Jun;35(2):69-74.
The mu opioid receptor (MOR) has been regarded as the main site of interaction with analgesics in major clinical use, particularly morphine. The repressor element-1 silencing transcription factor (REST) functions... -
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- Tapentadol: Can It Kill Two Birds with One Stone without Breaking Windows?
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Chang EJ, Choi EJ, Kim KH
- KMID: 2327635
- Korean J Pain.
- 2016 Jul;29(3):153-157.
- doi: 10.3344/kjp.2016.29.3.153
Tapentadol is a novel oral analgesic with a dual mode of action as an agonist of the µ-opioid receptor (MOR), and as a norepinephrine reuptake inhibitor (NRI) all in a... -
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- Effects of micro-Opioid Receptor Gene Polymorphism on Postoperative Nausea and Vomiting in Patients Undergoing General Anesthesia with Remifentanil: Double Blinded Randomized Trial
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Lee SH, Kim JD, Park SA, Oh CS, Kim SH
- KMID: 2155481
- J Korean Med Sci.
- 2015 May;30(5):651-657.
- doi: 10.3346/jkms.2015.30.5.651
Association between postoperative nausea and vomiting (PONV) and micro-opioid receptor A118G single nucleotide polymorphism (SNP) is undefined and might underlie inconsistent results of studies on PONV occurrence in patients undergoing... -
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- The Effect of Mu Agonist on Seizure in Hippocampus
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Choi BJ, Kim JS
- KMID: 2007316
- J Korean Child Neurol Soc.
- 2001 Oct;9(2):289-296.
PURPOSE: Mu agonists can be used in clinical conditions where threr is a risk of hypoxic neurosusceptibility. Fentanyl, one of mu agonists may serve as neuroprotection from brain ischemic injury... -
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- Pharmacotherapy for Alcohol Dependence: Anticraving Medications for Relapse Prevention
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Jung YC, Namkoong K
- KMID: 1110738
- Yonsei Med J.
- 2006 Apr;47(2):167-178.
- doi: 10.3349/ymj.2006.47.2.167
Alcohol dependence is a chronic disorder that results from a variety of genetic, psychosocial, and environmental factors. Relapse prevention for alcohol dependence has traditionally involved psychosocial and psychotherapeutic interventions. Pharmacotherapy,... -
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- The Analgesic Interactions Among Intrathecal Morphine, Ketorolac and L-NAME on Formalin-induced Pain in Rats
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Shim JH, Jun JH, Kim KH, Yeom JH, Suh JK
- KMID: 1860641
- Korean J Anesthesiol.
- 2002 Dec;43(6):780-790.
- doi: 10.4097/kjae.2002.43.6.780
BACKGROUND: Morphine has a direct action on morphine receptors in the brain and spinal cord. Intrathecally administered L-NAME, a nitric oxide synthase inhibitor, is known to have an antinociceptive effect... -
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- Effect of Intraperitoneal Nalbuphine-HCl on C-fos Expression in Rat Brain induced by Incisional Pain
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Park CS, Park CM, Joong JY
- KMID: 2104819
- J Korean Pain Soc.
- 2004 Jun;17(1):14-18.
- doi: 10.3344/jkps.2004.17.1.14
BACKGROUND: Nalbuphine-HCl (Nubain(R)), an agonist-antagonist of kappa3 and mu receptors, has limited analgesic or sedative effects, and an effect ceiling. It is generally accepted that c-fos is a marker of... -
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