- Effect of TrkA and p75NTR on the Survival of Neurons in the Cultured Organotypic Hippocampal Slice
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Yang DW, Kwon OJ, Kim YI, Kim BS
- KMID: 1636112
- J Korean Neurol Assoc.
- 2006 Dec;24(6):564-570.
BACKGROUND: Nerve growth factor (NGF) promotes the survival and differentiation of vertebrate neurons, and their actions are mediated by two classes of cell surface receptors: tyrosine kinase A receptor (TrkA)... -
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- Effect of Nerve Growth Factor on Cultured Rat Schwann Cells in Hyperglycemic Condition
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Hyung GY, Kim KH, Baek SH, Jang GY, Cho CG
- KMID: 1539926
- J Korean Diabetes Assoc.
- 2000 Feb;24(1):10-18.
BACKGROUND: Nerve growth factor (NGF) is produced in tissues innervafed by its responsive neurons. In the peripheral nervous system, NGF messenger RNA (mRNA) is produced in target fields of small... -
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- Mouse Nerve Growth Factor Facilitates the Growth of Interspinal Schwannoma Cells by Activating NGF Receptors
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Liu SY, Liu SZ, Li Y, Chen S
- KMID: 2463654
- J Korean Neurosurg Soc.
- 2019 Nov;62(6):626-634.
- doi: 10.3340/jkns.2019.0081
OBJECTIVE: Nerve growth factor (NGF) is a member of the neurotrophic factor family and plays a vital role in the physiological processes of organisms, especially in the nervous system. Many... -
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- Juxtaoral Organ of Chievitz: A Case Report
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Kim HS, Kim JH, Cha IH, Kim TS, Ryu MH, Kim J
- KMID: 1855949
- Korean J Pathol.
- 2005 Aug;39(4):265-268.
The juxtaoral organ of Chievitz is an intramuscular embryonic structure of neuroepithelial origin, and is found near the insertion of the pterygomandibular raphae. The juxtaoral organ of Chievitz has no... -
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- Soluble glucocorticoid-induced TNF receptor (sGITR) induces inflammation in mice
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Shin HH, Kim SG, Lee MH, Suh JH, Kwon BS, Choi HS
- KMID: 1093607
- Exp Mol Med.
- 2003 Oct;35(5):358-364.
Glucocorticoid-induced TNF receptor (GITR) was a new member of the TNF/nerve growth factor receptor (TNFR/ NGFR) family and induced in murine T cells by dexamathasone. Recombinant soluble GITR (sGITR) induced... -
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- Neuronal Cytoskeletal Abnormalities and Neurotrophin Receptor Immunoreactivity in Severe Cerebral Cortical Dysplasia
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Kim JY, Roh JK, Chung CK
- KMID: 2186049
- J Korean Neurol Assoc.
- 2000 Mar;18(2):199-210.
BACKGROUND: Cerebral cortical dysplasia (CD) is one of the important causes of intractable epilepsies and characterized histologically by disorganized cortical lamination and cytomegalic dysplastic neurons. Although various cytoskeletal abnormalities have... -
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- Neuroprotection signaling pathway of nerve growth factor and brain-derived neurotrophic factor against staurosporine induced apoptosis in hippocampal H19-7 cells
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Nguyen TL, Kim CK, Cho JH, Lee KH, Ahn JY
- KMID: 1104385
- Exp Mol Med.
- 2010 Aug;42(8):583-595.
- doi: 10.3858/emm.2010.42.8.060
Neurotrophins protect neurons against excitotoxicity; however the signaling mechanisms for this protection remain to be fully elucidated. Here we report that activation of the phosphatidyl inositol 3 kinase (PI3K)/Akt pathway... -
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- Induction of nitric oxid esynthase(NOS) by soluble glucocorticoid induced tumor necrosis factor receptor(sGITR) is modulated by IFN-g in murine macrophage
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Shin HH, Lee HW, Choi HS
- KMID: 1094698
- Exp Mol Med.
- 2003 Jun;35(3):175-180.
Earlier study showed that glucocorticoid induced tumor necrosis factor receptor (GITR), a new TNFR family, activated murine macrophages to express inducible nitric oxide synthase (iNOS) and to generate nitric oxide... -
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- In vivo ligation of glucocorticoid-induced TNF receptor enhances the T-cell immunity to herpes simplex virus type 1
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La S, Kim E, Kwon B
- KMID: 1056231
- Exp Mol Med.
- 2005 Jun;37(3):193-198.
GITR (glucocorticoid-induced TNF receptor) is a recently identified member of the TNF receptor superfamily. The receptor is preferentially expressed on CD4+CD25+ regulatory T cells and GITR signals break the suppressive... -
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- Serum concentrations of soluble 4-1BB and 4-1BB ligand correlated with the disease severity in rheumatoid arthritis
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Jung HW, Choi SW, Choi JI, Kwon BS
- KMID: 755660
- Exp Mol Med.
- 2004 Feb;36(1):13-22.
Rheumatoid arthritis (RA) is a multifactorial autoimmune disease whose etiopathogenesis is not well understood. Although soluble (s) forms of 4-1BB (s4-1BB) and 4-1BB legand (s4-1BBL) have been detected in the... -
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- Constitutive expression of 4-1BB on T cells enhances CD4+ T cell responses
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Kim J, Choi SP, La S, Seo JS, Kim KK, Nam SH, Kwon B
- KMID: 1119332
- Exp Mol Med.
- 2003 Dec;35(6):509-517.
4-1BB, a transmembrane molecule, member of the tumor necrosis factor receptor superfamily, is an important costimulatory molecule in the immune response, plays a key role in the clonal expansion and... -
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- CD137 induces adhesion and cytokine production in human monocytic THP-1 cells
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Choi JW, Lee HW, Roh GS, Kim HH, Kwack KB
- KMID: 755745
- Exp Mol Med.
- 2005 Apr;37(2):78-85.
CD137, which is expressed on activated T cells, plays a critical role in inflammatory responses. However, the exact role that CD137 plays in monocytes is not fully known. Here we... -
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- The Association of the Activation-Inducible Tumor Necrosis Factor Receptor and Ligand with Lumbar Disc Herniation
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Park MS, Lee HM, Hahn SB, Moon SH, Kim YT, Lee CS, Jung HW, Kwon BS, Riew KD
- KMID: 1122623
- Yonsei Med J.
- 2007 Oct;48(5):839-846.
- doi: 10.3349/ymj.2007.48.5.839
PURPOSE: Herniated nucleus pulposus fragments are recognized by the immune system as a foreign-body, which results in an autoimmune reaction. Human activation-inducible tumor necrosis factor receptor (AITR) and its... -
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