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A Possible Role of Kainate Receptors in C2C12 Skeletal Myogenic Cells

Park JY, Han J, Hong SG

  • KMID: 1607524
  • Korean J Physiol Pharmacol.
  • 2003 Dec;7(6):375-379.
Ca2+ influx appears to be important for triggering myoblast fusion. It remains, however, unclear how Ca2+ influx rises prior to myoblast fusion. Recently, several studies suggested that NMDA receptors may...
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Excitotoxic change of Hippocampal Neuron by Kainic Acid in Rat Brain

Chang SH, Kim DE, Kwon OS, Kim KY, Lee WB, Kim DC

  • KMID: 2342431
  • J Korean Neurol Assoc.
  • 1994 Sep;12(3):382-396.
The excitotoxic effect of kainic acid on dendrites and neuronal cell bodies of hippocampus and dentate gyrus was studied with time (1, 4, 8, 16 hours, 2, 7, 14 days)...
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Excitotoxic Cell Death in Cultured Retinal Neurons

Yoon YH, Shim MJ, Lee J

  • KMID: 2123633
  • J Korean Ophthalmol Soc.
  • 1997 Nov;38(11):1987-1999.
We examined excitotoxicity, putatively a major mechanism of ischemic neuronal death, in primary rat retinal cultures. Retinal cultures were prepared from newborn rats (day 1 or 2). Exposure of these...
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Type II and III Taste Bud Cells Preferentially Expressed Kainate Glutamate Receptors in Rats

Lee SB, Lee CH, Kim SN, Chung KM, Cho YK, Kim KN

Glutamate-induced cobalt uptake reveals that non-NMDA glutamate receptors (GluRs) are present in rat taste bud cells. Previous studies involving glutamate induced cobalt staining suggest this uptake mainly occurs via kainate...
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Neuroprotective Effects of SYM 2081, Targeting Kainate Receptors in the Neonatal Hypoxic-Ischemic Brain Injury

Lee JH, Lee EJ, Jang YY, Jeong JE, Chung HL, Kim WT

PURPOSE: Glutamate induced excitotoxicity has been implicated as a major factor of central neuronal death in neonatal hypoxic-ischemic (HI) injury. Kainate receptors (KARs) are one of glutamatergic receptors involving glutamate...
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Hypoxia-A Possibility in Fibromyalgia Syndrome Pathogenesis

Kim SH, Moon IS

  • KMID: 2202233
  • J Korean Rheum Assoc.
  • 2006 Sep;13(3):218-225.
OBJECTIVE: We studied the expression of pain-related molecules such as substance P involved in chronic pain of fibromyalgia syndrome (FMS) patients using rat cortical cells in hypoxia. METHODS: We sacrificed pregnant...
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Distribution and Expression of Kainate(KA) Receptor Subunits in Moderate Hypoxic Newborn Piglet Brain

Chang CH, Kim WT

  • KMID: 1829635
  • J Korean Pediatr Soc.
  • 1999 Dec;42(12):1651-1660.
PURPOSE: The mechanism of hypoxic damage is mainly intracellular influx of calcium ions through the glutamate ionotropic receptor. This study was performed to determine alterations in distribution and expression of...
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Alpha1-Adrenoceptor Antagonists Improve Memory by Activating N-methyl-D-Aspartate-Induced Ion Currents in the Rat Hippocampus

Kim CH, Ko IG, Kim SE, Shin MS, Kang YH, Cho JW, Shin KM, Kim CJ, Lim BV, Kim KH

PURPOSE: Alpha1 (alpha1)-adrenoceptor antagonists are widely used to treat lower urinary tract symptoms. These drugs not only act on peripheral tissues, but also cross the blood-brain barrier and affect the...
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Expression of KA1 kainate receptor subunit in the substantia gelatinosa of the trigeminal subnucleus caudalis in mice

Park SA, Park SJ, Han SK

The KA1 kainate receptor (KAR) subunit in the substantia gelatinosa (SG) of the trigeminal subnucleus caudalis (Vc) has been implicated in the processing of nociceptive information from the orofacial region....
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