- Beyond Vasodilator: Anti-Apoptotic Effect of Endothelin Receptor Antagonist
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Chang SA
- KMID: 2223894
- Korean Circ J.
- 2014 Mar;44(2):74-75.
- doi: 10.4070/kcj.2014.44.2.74
No abstract available. -
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- Expression of Endothelin-1 and Its Receptors in Cisplatin-Induced Acute Renal Failure in Mice
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Lee S, Ahn D
- KMID: 1838352
- Korean J Physiol Pharmacol.
- 2008 Aug;12(4):149-153.
- doi: 10.4196/kjpp.2008.12.4.149
Endothelin-1 (ET-1) is unequivocally elevated in the kidney with ischemic acute renal failure (ARF), whereas ET receptors (ET(A)R and ET(B)R) are variably expressed. Although renal functional and structural changes are... -
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- The Effect of Endothelin on Osteoblast
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Jeon HS, Kim YT, Chang JS, Kim KY, Yoon HK, Kim CY
- KMID: 2141816
- J Korean Orthop Res Soc.
- 1998 Apr;1(1):1-13.
Endothelin derived from the endothelial cells of microvessel is a potent vasoactive peptide, which has various physiologic actions in many internal organs. The fact that endothelin receptors are present on... -
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- Endothelin-mediated Intracellular Calcium Mobilization in Cultured Bovine Corneal Endothelium
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Hahn TW, Cha SH, Lee KH, Kim JH
- KMID: 2336733
- J Korean Ophthalmol Soc.
- 1999 Jan;40(1):31-39.
To investigate the effect of endothelin on intracellular free calcium ([Ca(2+)]i) mobilization and the existence of the endothelin receptor in cultured bovine corneal endothelial cells(BCEC), endothelin-1(ET-1) -induced [Ca(2+)]i increase was... -
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- Changes in Endothelin Receptor Type B and Neuronal Nitric Oxide Synthase in Puromycin Aminonucleoside-Induced Nephrotic Syndrome
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Bae EH, Kim SW
- KMID: 2285406
- Korean J Physiol Pharmacol.
- 2010 Aug;14(4):223-228.
- doi: 10.4196/kjpp.2010.14.4.223
The collecting duct endothelin (ET) system, which involves ET-1 and its two receptors, may play a role in the regulation of renal sodium in association with the nitric oxide synthase... -
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- Device Closure of a Large Atrial Septal Defect in a Patient with Severe Pulmonary Arterial Hypertension after 1 Year Use of an Oral Endothelin Receptor Antagonist
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Jung IH, Lee SY, Lee SJ, Lee JY, Park NJ, Ahn DS, Jung JH, Shin DH, Lim DS
- KMID: 1500194
- J Cardiovasc Ultrasound.
- 2013 Sep;21(3):140-144.
- doi: 10.4250/jcu.2013.21.3.140
The presence of severe pulmonary arterial hypertension (PAH) in patients with atrial septal defect (ASD) is still thought to preclude shunt closure, although there are several reports of good clinical... -
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- The first Korean case of Waardenburg-Shah syndrome with novel endothelin receptor type B mutations
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Lee ES, Ko JM, Moon JS
- KMID: 2401812
- J Genet Med.
- 2017 Dec;14(2):86-89.
- doi: 10.5734/JGM.2017.14.2.86
Waardenburg syndrome (WS) is a rare genetic disorder, including clinical features of pigmentary abnormalities of irides, skin, hair and sensorineural hearing loss and facial dysmorphism. Among the four types, WS... -
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- Pulmonary Hypertension in Patient with Neurofibromatosis Type 1
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Lee YM, Yang TH, Jung H, Oh TS, Song JH, Yu SJ
- KMID: 2400266
- Kosin Med J.
- 2017 Dec;32(2):227-232.
- doi: 10.7180/kmj.2017.32.2.227
Neurofibromatosis type 1 (NF1) is a rare genetic disease. Precapillary pulmonary hypertension (PH) with NF1 is an extremely severe complication. A 65-year-old woman was admitted in our hospital with 3-year... -
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- Expression Changes of Endothelin-1, Endothelin Receptor A and B in the Cochlea after Noise Exposure
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Hur GM, Lyu AR, Han WK, Choi JW, Rha KS, Park YH
- KMID: 2277755
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2013 May;56(5):278-285.
- doi: 10.3342/kjorl-hns.2013.56.5.278
BACKGROUND AND OBJECTIVES: There are several evidences of reduced cochlea blood flow after noise exposure in the cochlea. However, the pathophysiology of blood flow change is still obscure, and endothelins,... -
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- Successful Treatment of Newly Developed, Intractable Digital Ulcers and Gangrene with Bosentan in Systemic Sclerosis
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Tag HS, Jun SM, Lee SG, Park EK, Koo DW, Kim GT
- KMID: 2326736
- J Rheum Dis.
- 2016 Jun;23(3):193-197.
- doi: 10.4078/jrd.2016.23.3.193
In systemic sclerosis, digital ulcers and gangrene are somewhat common clinical characteristics of obliterative vasculopathy. These manifestations increase morbidities, such as pain, infections, and acroosteolysis. However, patient responses to the... -
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- Contractile Responses to Endothelins in Isolated Arteries from Human Uterus
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Choi OH, Jang MK, Rhim BY
- KMID: 2261368
- Korean J Obstet Gynecol.
- 1999 Mar;42(3):582-590.
OBJECTIVE: We examined the vasoconstricting poperties of endothelin (ET) on isolated arteries from pregnant as well as non-pregnant uterus. METHODS: Arteries of the uterus were obtained from both hysterectomized uterus... -
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- Clinical Year in Review of Interstitial Lung Diseases: Focused on Idiopathic Interstitial Pneumonia
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Lee WY
- KMID: 2319248
- Tuberc Respir Dis.
- 2009 Oct;67(4):275-280.
Interstitial lung disease (ILD) is a group of diseases characterized by pulmonary interstitial inflammation. Finally the inflammation results in pulmonary fibrosis and impairment of oxygen transportation. The causes of idiopathic... -
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- Alteration in Endothelin Receptor-Mediated Responses in Femoral Arteries from Hyperlipidemic Rabbits
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Suh KT, Lee CB, Shim WS, Rhim BY
- KMID: 2189546
- J Korean Orthop Assoc.
- 1999 Feb;34(1):147-155.
OBJECTIVE: To investigate the roles of ET in the regulation of peripheral vascular tone, we studied the effect of hyperlipidemia on vascular responsiveness in femoral arteries from rabbits with control... -
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- Quantification of Endothelin-1 mRNA and Endothelin Receptor B mRNA from Cortex and Inner Medulla of Mouse Kidney Using Real-time RT-PCR
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Ahn DW
- KMID: 2254352
- Korean J Nephrol.
- 2004 Mar;23(2):188-194.
BACKGROUND: Endothelin-1 (ET-1) production and ET receptor type B (ETRB) density in the kidney increase along the corticomedullary axis. Northern blot showed that preproET-1 mRNA message was higher in medulla... -
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- Endothelium-dependent and Independent Responsiveness to Endothelin in Porcine Coronary Artery
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Hong MK, Kim JJ, Lee CW, Park SW, Park SJ
- KMID: 1858313
- Korean Circ J.
- 1998 Dec;28(12):1993-2001.
- doi: 10.4070/kcj.1998.28.12.1993
BACKGROUND: The purpose of this study was to investigate the mechanism of endothelium-dependent and independent responses to endothelins (ETs) in porcine coronary artery. METHODS: The vascular rings of left anterior... -
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- New drugs for treatment of hypertension
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Park CG
- KMID: 1927357
- Korean J Med.
- 2004 Nov;67(5):461-466.
Recently several kinds of new antihypertensive agents were introduced. Diuretics such as indapamide, metyrazone and eprelerone have less side effects compared to thiazide, and have an effect in renal insufficiency.... -
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- Bosentan Attenuates Compensatory Left Ventricular Hypertrophy Induced by Aortocaval Fistula in Rats
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Lee DS, Kim DK, Choi SM, Kim YK, Ko BH, Jung YW
- KMID: 1859019
- Korean Circ J.
- 2005 Sep;35(9):665-671.
- doi: 10.4070/kcj.2005.35.9.665
BACKGROUND AND OBJECTIVES: Endothelin-1 (ET-1) is increased in advanced congestive heart failure and pulmonary hypertension associated with increased pulmonary blood flow. The role of ET-1 and the protective effect of... -
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- The Role of Chronic Endothelin Antagonism for Preserving Erectile Function in Experimental Diabetic Rats
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Yang DY, Kim SY, Kim H, Hyun JS, Hellstrom
- KMID: 2226687
- Korean J Androl.
- 2002 Aug;20(2):75-81.
PURPOSE: This study was designed to investigate the role of chronic endothelin receptor antagonism to preserve erectile function in diabetic rats. MATERIALS AND METHODS: Forty adult male Sprague-Dawley rats (250-350 gm)... -
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- Therapeutic effect of prostaglandin E1 in monocrotaline-induced pulmonary arterial hypertension rats
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Lee JC
- KMID: 2390427
- Anat Cell Biol.
- 2017 Mar;50(1):60-68.
- doi: 10.5115/acb.2017.50.1.60
Pulmonary arterial hypertension (PAH) is a severe pulmonary vascular disease characterized by sustained increase in pulmonary arterial pressure and excessive thickening and remodeling of distal small pulmonary arteries. During disease... -
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- Gene Expression of Endothelin-1 and Endothelin Receptor A on Monocrotaline-Induced Pulmonary Hypertension in Rats After Bosentan Treatment
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Lim KA, Kim KC, Cho MS, Lee BE, Kim HS, Hong YM
- KMID: 1456139
- Korean Circ J.
- 2010 Sep;40(9):459-464.
- doi: 10.4070/kcj.2010.40.9.459
BACKGROUND AND OBJECTIVES: Endothelin (ET)-1, a potent endothelium-derived vasoconstrictor peptide, has a potential pathophysiologic role in pulmonary hypertension. Bosentan, a dual ET receptor (ET(A)/ET(B)) antagonist, is efficacious in treatment of... -
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