- D3 Receptor Gene Variant and Tardive Dyskinesia in Schizophrenic Patients
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Nam JW, Lee MS
- KMID: 2340345
- J Korean Neuropsychiatr Assoc.
- 1999 Jul;38(4):853-860.
Tardive dyskinesia(TD)is one of the serious side effects caused by long-term treatment with neuroleptic medication. It has been known that dopamine D3 receptors are mainly located on the postsynaptic membrane... -
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- The Association between Polymorphism of the Dopamine D3 Receptors and Concentrations of Plasma Homovanillic and 5-hydroxyindoleacetic Acid, and Therapeutic Response of chronic Schizophrenic Patients
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Jeong GJ, Lee MS, Kim SY, Kang DY, Kwak DI
- KMID: 2142167
- J Korean Soc Biol Psychiatry.
- 2001 Jun;8(1):116-122.
OBJECTIVES: Schizophrenia manifests a variety of interindividual differences in therapeutic response to antipsychotics. This might be attributable to dopamine and serotonin receptors that a important target for various antipsychotics, and... -
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- Molecular Signature That Determines the Acute Tolerance of G Protein-Coupled Receptors
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Min C, Zhang X, Zheng M, Sun N, Acharya S, Zhang X, Kim KM
- KMID: 2378801
- Biomol Ther.
- 2017 May;25(3):239-248.
- doi: 10.4062/biomolther.2016.193
Desensitization and acute tolerance are terms used to describe the attenuation of receptor responsiveness by prolonged or intermittent exposure to an agonist. Unlike desensitization of G protein-coupled receptors (GPCRs), which... -
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- Association Study between Treatment Response of Amisulpride and Dopamine D3 Receptor Gene Polymorphisms
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Kang SG, Lee HJ, Lee SJ, Choi TY, Woo J, Kim J, Jung SW, Koo BH, Lee K, Kim JL, Chee IS, Lee J
- KMID: 2250698
- Korean J Biol Psychiatry.
- 2013 Sep;20(3):91-96.
OBJECTIVES: The aim of this study is to evaluate the association between rs6280 and rs905568 genetic polymorphism of DRD3 gene and the treatment response of amisulpride. METHODS: After six weeks treatment... -
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