- Immunohistochemical Analysis of Fas-associated Death Domain Protein Expression in Stomach Cancers
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Lee SH, Lee JW, Park WS, Lee JY, Yoo NJ
- KMID: 2372720
- J Korean Gastric Cancer Assoc.
- 2003 Jun;3(2):80-83.
PURPOSE: Evidence exists that dysregulation of apoptosis is involved in the pathogenesis of cancer development. Fas- associated death domain (FADD) protein, an adaptor protein of death receptors, is a critical... -
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- Involvement of Up-regulation of Death Receptors and Bim in Hispolon-mediated TNF-related Apoptosis-inducing Ligand Sensitization in Human Renal Carcinoma
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Yun JM, Min KJ, Kwon TK
- KMID: 2468797
- J Cancer Prev.
- 2019 Sep;24(3):155-162.
- doi: 10.15430/JCP.2019.24.3.155
BACKGROUND: Hispolon has been shown to possess antitumor effects in various cancer cells. However, the underlying mechanisms are not fully understood. In this study, we evaluated the sensitizing effect of... -
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- Eosinophil Survival and Apoptosis in Health and Disease
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Park YM, Bochner BS
- KMID: 2260594
- Allergy Asthma Immunol Res.
- 2010 Apr;2(2):87-101.
- doi: 10.4168/aair.2010.2.2.87
Eosinophilia is common feature of many disorders, including allergic diseases. There are many factors that influence the production, migration, survival and death of the eosinophil. Apoptosis is the most common... -
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- Effects of Cycloheximide and Dexamethasone on Fas - Mediated Apopthsis in Primary Human Astrocytes
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Choi C, Choi IH, Huh K
- KMID: 1550755
- Korean J Immunol.
- 1999 Dec;21(4):361-368.
Astrocytes are major glial cells in central nervous system (CNS) and are known to express death receptors or ligands that can induce apoptosis of astrocytes or other brain cells. We... -
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- Bcl-2 Knockdown Accelerates T Cell Receptor-Triggered Activation-Induced Cell Death in Jurkat T Cells
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Lee YJ, Won TJ, Hyung KE, Lee MJ, Moon YH, Lee IH, Go BS, Hwang KW
- KMID: 2285494
- Korean J Physiol Pharmacol.
- 2014 Feb;18(1):73-78.
- doi: 10.4196/kjpp.2014.18.1.73
Cell death and survival are tightly controlled through the highly coordinated activation/inhibition of diverse signal transduction pathways to insure normal development and physiology. Imbalance between cell death and survival often... -
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- Analysis of PD-L1 expression in salivary duct carcinoma with its efficacy as a tumor marker
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Lee YJ, Koh YW, Yoon SO, Ryu HJ, Kim HR, Shin HA
- KMID: 2454254
- Korean J Head Neck Oncol.
- 2019 May;35(1):13-20.
- doi: 10.21593/kjhno/2019.35.1.13
BACKGROUND/OBJECTIVES: Despite multiple approaches of treatments for salivary duct carcinoma, there has been a need for more successful treatment methods because of its poor prognosis. Treatment options like immunotherapy using... -
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- Immunohistochemical Analysis for the Expression of DR5 TRAIL Receptor and p53 in Non-small Cell Lung Cancer
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Lee KY, Lee JH, Kim SJ, Yoo KH
- KMID: 1970178
- Tuberc Respir Dis.
- 2008 Apr;64(4):278-284.
- doi: 10.4046/trd.2008.64.4.278
BACKGROUND: TRAIL is a promising anticancer agent which induces selective tumor cell death due to a unique receptor system that includes death receptors and decoy receptors. DR5 TRAIL receptor is... -
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- Extracellular acidity enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis via DR5 in gastric cancer cells
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Hong R, Han SI
- KMID: 2419001
- Korean J Physiol Pharmacol.
- 2018 Sep;22(5):513-523.
- doi: 10.4196/kjpp.2018.22.5.513
The tumor microenvironment greatly influences cancer cell characteristics, and acidic extracellular pH has been implicated as an essential factor in tumor malignancy and the induction of drug resistance. Here, we... -
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- Anti-Proliferative Activities of Vasicinone on Lung Carcinoma Cells Mediated via Activation of Both Mitochondria-Dependent and Independent Pathways
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Dey T, Dutta P, Manna P, Kalita J, Boruah HP, Buragohain AK, Unni B
- KMID: 2420392
- Biomol Ther.
- 2018 Jul;26(4):409-416.
- doi: 10.4062/biomolther.2017.097
Vasicinone, a quinazoline alkaloid from Adhatoda vasica Nees. is well known for its bronchodilator activity. However its antiproliferative activities is yet to be elucidated. Here-in we investigated the anti-proliferative effect... -
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- Induction of Apoptosis Scutellaria baicalensis Georgi Root Extract by Inactivation of the Phosphatidyl Inositol 3-kinase/Akt Signaling Pathway in Human Leukemia U937 Cells
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Choi EO, Hwang HJ, Choi YH
- KMID: 2447436
- J Cancer Prev.
- 2019 Mar;24(1):11-19.
- doi: 10.15430/JCP.2019.24.1.11
BACKGROUND: The roots of Scutellaria baicalensis Georgi (Labiatae) have been widely used in traditional medicine for treatment of various diseases. In this study, we investigated the effects of ethanol extracts... -
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- Therapeutic Effects of Synthetic Antimicrobial Peptides, TRAIL and NRP1 Blocking Peptides in Psoriatic Keratinocytes
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Ryu S, Broussard , Youn C, Song B, Norris D, Armstrong , Kim B, Song PI
- KMID: 2447209
- Chonnam Med J.
- 2019 May;55(2):75-85.
- doi: 10.4068/cmj.2019.55.2.75
Psoriasis is a chronic, recurrent, heterogeneous, cutaneous inflammatory skin disease for which there is no cure. It affects approximately 7.5 million people in the United States. Currently, several biologic agents... -
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- Trichostatin A induces apoptosis in lung cancer cells via simultaneous activation of the death receptor-mediated and mitochondrial pathway
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Kim HR, Kim EJ, Yang SH, Jeong ET, Park C, Lee JH, Youn MJ, So HS, Park R
- KMID: 1115939
- Exp Mol Med.
- 2006 Dec;38(6):616-624.
Trichostatin A (TSA), originally developed as an antifungal agent, is one of potent histone deacetylase (HDAC) inhibitors, which are known to cause growth arrest and apoptosis induction of transformed cells,... -
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