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Expression of Chemokine Receptors in Ovarian Cancer Tissue

Jo HJ, Lee SY, Park CS, An HJ, Oh YK, Kim SH, Na YJ, Kim IH, Lee C, Kim SJ

  • KMID: 2272160
  • Korean J Obstet Gynecol.
  • 2003 Sep;46(9):1746-1753.
OBJECTIVE: We investigated the expression of chemokine receptors in human ovarian cancer to understand the role of chemokines in ovarian cancer development and metastasis. METHODS: Twenty-two cases of epithelial ovarian...
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Chemokine Systems Link Obesity to Insulin Resistance

Ota T

Obesity is a state of chronic low-grade systemic inflammation. This chronic inflammation is deeply involved in insulin resistance, which is the underlying condition of type 2 diabetes and metabolic syndrome....
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Analysis of Intraocular Chemokine and Chemokine Receptor in Patients with HLA-B27-associated Anterior Uveitis

Kim TW, Chung H, Yu HG

  • KMID: 2337665
  • J Korean Ophthalmol Soc.
  • 2008 Sep;49(9):1475-1482.
PURPOSE: To evaluate the expression of chemokine and chemokine receptors in the aqueous humor (AH) of patients with recurrent anterior uveitis (AU) in terms of HLA-B-27-association. METHODS: Patients with endogenous uveitis...
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Induction and Expression of Chemokines and Their Receptors in Human Mast Cell Line ( HMC - 1 )

Ha YM

  • KMID: 1550749
  • Korean J Immunol.
  • 1999 Dec;21(4):335-342.
The mast cell is an essential effector cell in allergic inflammation through its capacity to respond to IgE dependent activation. Mast cells also participate in the modulation of physiologic processes,...
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Immunohistochemical Study on the Expression of Chemokines and Chemokine Receptors in Psoriasis

Choi YS, Lim TW, Kim NI

  • KMID: 1595183
  • Korean J Dermatol.
  • 2001 Apr;39(4):435-445.
BACKGROUND: Psoriatic keratinocytes express CXC chemokines like IL-8 and GRO-alpha, and CC chemokines like MCP-1 and RANTES, which have a significant role in the accumulation of inflammatory cells in psoriatic...
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Chemokine Receptors Expression in MSCs: Comparative Analysis in Different Sources and Passages

Heirani-Tabasi A, Toosi S, Mirahmadi , Mishan MA, Bidkhori H, Bahrami AR, Behravan J, Naderi-Meshkin H

MSC-based therapy is providing a cure for degenerative diseases with unmet medical need and usually iliac crest bone marrow (ICBM) are being applied in clinics. Alternative sources, including adipose tissue...
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Identification of Inducible Murine Mast Cell Genes by Suppression PCR - Based Subtractive Hybridization

Ha YM

  • KMID: 1550747
  • Korean J Immunol.
  • 1999 Dec;21(4):327-334.
The mast cell is an essential effector cell in allergic inflammation through its capacity to respond to IgE dependent activation. Mast cells also participate in the modulation of physiologic processes,...
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Differential Chemokine Signature between Human Preadipocytes and Adipocytes

Ignacio RM, Gibbs CR, Lee ES, Son DS

Obesity is characterized as an accumulation of adipose tissue mass represented by chronic, low-grade inflammation. Obesity-derived inflammation involves chemokines as important regulators contributing to the pathophysiology of obesity-related diseases such...
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Chemokine Receptor CCR3 Expression in Malignant Cutaneous Tumors

Lee YJ, Kim DH, Lee SH, Nam HS, Roh MR, Cho MK

BACKGROUND: Chemokines and their receptors are important players in tumorigenesis by facilitating tumor proliferation and metastasis. Little is known about the possible function of chemokine receptors in relation to the...
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Stromal cell-derived factor-1 (SDF-1) expression in the oral squamous cell carcinoma

Kim KW, Han SJ, Roh KS

PURPOSE: Chemokines are structurally related, small polypeptide signaling molecules that bind to and activate a family of transmembrane G proteincoupled receptors, the chemokine receptors. Recently, interaction between the chemokine receptor...
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Association of Chemokines and Chemokine Receptor Expression with Monocytic-Myeloid-Derived Suppressor Cells during Tumor Progression

Seo EH, Namgung JH, Oh CS, Kim SH, Lee SH

Myeloid-derived suppressor cells (MDSCs) are highly immunosuppressive myeloid cells that show increased expression in cancer patients; however, the molecular mechanisms underlying their generation and function are unclear. Whereas granulocytic-MDSCs correlate...
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Activation and Recruitment of Regulatory T Cells via Chemokine Receptor Activation in Trichinella spiralis-Infected Mice

Ahn JB, Kang SA, Kim DH, Yu HS

As most infections by the helminth parasite elicit the recruitment of CD4+CD25+Foxp3+ T (T(reg)) cells, many scientists have suggested that these cells could be used for the treatment of immune-mediated...
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The Correlation between the Tc2 Cells and the CCR4 Expression and the PASI Score in the Peripheral Blood of Psoriasis Patients

Lee KY, Lee YK, Kim KH, Kim KH

  • KMID: 2301801
  • Korean J Dermatol.
  • 2010 Nov;48(11):919-924.
BACKGROUND: Psoriasis is a chronic relapsing skin disorder that is characterized by abnormal epidermal proliferation, inflammation and angiogenesis. It causes emotional and social consequences that go far beyond the skin;...
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Mesenchymal Stem Cell-Specific Chemokines for Articular Cartilage Repair

Park MS, Kim YH, Lee JW

  • KMID: 2314091
  • Osteoporosis.
  • 2011 Apr;9(1):57-65.
OBJECTIVES: Bone marrow-derived mesenchymal stem cells (BMSCs) are a good source for cartilage repair. Chondral defects do not heal spontaneously due to a lack of chondrocytes at the defect site...
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In vitro migration capacity of human adipose tissue-derived mesenchymal stem cells reflects their expression of receptors for chemokines and growth factors

Baek SJ, Kang SK, Ra JC

The homing properties of adipose tissue-derived mesenchymal stem cells (AdMSCs) have stimulated intravenous applications for their use in stem cell therapy. However, the soluble factors and corresponding cellular receptors responsible...
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Sarcoplasmic reticulum Ca²⁺ ATPase 2 (SERCA2) reduces the migratory capacity of CCL21-treated monocyte-derived dendritic cells

Hong CY, Lee HJ, Choi NR, Jung SH, Vo MC, Hoang MD, Kim HJ, Lee JJ

The migration of dendritic cells (DCs) to secondary lymphoid organs depends on chemoattraction through the interaction of the chemokine receptors with chemokines. However, the mechanism of how lymphoid chemokines attract...
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RANTES, MCP-1, CCR2, CCR5, CXCR1 and CXCR4 Gene Polymorphisms are not Associated with the Outcome of Hepatitis B Virus Infection: Results from a Large Scale Single Ethnic Population

Cheong JY, Cho SW, Choi JY, Lee JA, Kim MH, Lee JE, Hahm KB, Kim JH

Recovery from hepatitis B virus (HBV) infection depends on the cellular immune responses. Chemokines and their receptors play significant roles in immune defense. This study was undertaken to investigate the...
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Chemokine Receptor Expression of Hepatitis B Virus-Specific CD8+ Lymphocyte in Chronic B Viral Infection

Lee CK, Suh JH, Cho YS, Han KH, Chung JB, Chon CY, Moon YM

  • KMID: 863111
  • Korean J Hepatol.
  • 2002 Dec;8(4):363-370.
BACKGROUND/AIMS: The protective role of HBV-specific CD8+ cells is dependent on their ability to efficiently migrate to the infected liver, where they may exert an effector function. The migratory...
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Serosal Cavities Contain Two Populations of Innate-like integrin α4highCD4+ T Cells, Integrin α4β1+α6β1+α4β7− and α4β1+α6β1−α4β7+ Cells

Yang JI, Park C, Kho I, Lee S, Suh KS, Kim TJ

We previously reported peritoneal innate-like integrin α4 (CD49d)highCD4+ T cells that provided help for B-1a cells. Here we analyzed the expression of various integrin chains on the peritoneal and pleural...
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p38 MAPK and ERK activation by 9-cis-retinoic acid induces chemokine receptors CCR1 and CCR2 expression in human monocytic THP-1 cells

Ko J, Yun CY, Lee JS, Kim JH, Kim IS

  • KMID: 1094653
  • Exp Mol Med.
  • 2007 Apr;39(2):129-138.
9-cis-retinoic acid (9CRA) plays an important role in the immune response; this includes cytokine production and cell migration. We have previously demonstrated that 9CRA increases expression of chemokine receptors CCR1...
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