- Gene Expression Regulation by Agonist-Independent Constitutive Signaling of Melanocortin-1 Receptor
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Seong I, Kim J
- KMID: 2169425
- Endocrinol Metab.
- 2014 Jun;29(2):179-184.
- doi: 10.3803/EnM.2014.29.2.179
BACKGROUND: Melanocortin-1 receptor (Mc1r), a key signaling receptor for melanogenesis, has been reported to mediate migration of B16F10 melanoma cells. Interestingly, this activity appears to be a part of the... -
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- The Expression of the alpha-Melanocyte Stimulating Hormone (alpha-MSH) and Melanocortin-1 Receptor (MC1R) in the Epidermis of the Vitiligo
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Cha YC, Lee HJ, Lee SJ, Na GY, Chung SL
- KMID: 2302963
- Korean J Dermatol.
- 2003 Jun;41(6):690-695.
BACKGROUND: Vitiligo is a skin disease that is characterized by the loss of cutaneous pigmentation. alpha-Melanocyte stimulating hormone (alpha-MSH) is a neuroimmunomodulating peptide derived from proopiomelanocortin, and melanocortin-1 receptor (MC1R)... -
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- The effects of BMS-470539 on lipopolysaccharide-induced acute lung injury
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Jang EA, Kim JY, Tin TD, Song JA, Lee SH, Kwak SH
- KMID: 2449367
- Acute Crit Care.
- 2019 May;34(2):133-140.
- doi: 10.4266/acc.2019.00507
BACKGROUND: Overactivation of inflammatory cells, including macrophages and neutrophils, is associated with acute lung injury. BMS-470539 is a selective agonist of melanocortin 1 receptor, which triggers the inhibition of proinflammatory... -
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- cDNA Microarray Analysis of Differential Gene Expression in Gastric Cancer Cells Sensitive and Resistant to 5-Fluorouracil and Cisplatin
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Ahn MJ, Yoo YD, Lee KH, Ahn JI, Yu DH, Lee HS, Oh HS, Choi JH, Lee YS
- KMID: 1743356
- Cancer Res Treat.
- 2005 Feb;37(1):54-62.
PURPOSE: Gastric cancer is one of the most prevalent cancers worldwide. 5-fluorouracil (5-FU) and cisplatin are the most commonly used drugs for the treatment of gastric cancer. However, a significant... -
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