- Cholinergic activity related to cardiovascular regulation in rostral ventrolateral medulla of spontaneously hypertensive rats
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Lee SY, Lee SB
- KMID: 1917067
- Korean J Physiol Pharmacol.
- 1999 Feb;3(1):29-34.
The hyperactivity of cholinergic system in the RVLM of spontaneously hypertensive rats (SHR) may contribute to the sustained elevation of blood pressure. However, the hyperactivity mechanisms of cholinergic system are controversial. Thus, to... -
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- Changes in Myogenic Tone in Spontaneously Hypertensive Rat: Role of RhoA and Protein Kinase C
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Seo JP, Ryu SK, Kang NY, Ahn DS, Lee YH
- KMID: 1938907
- Korean Circ J.
- 2002 Mar;32(3):257-267.
- doi: 10.4070/kcj.2002.32.3.257
BACKGROUND AND OBJECTIVES: The myogenic response was originally described as a contraction of a blood vessel that occurred following an increase in intravascular distending pressure. Conversely, a reduction in intravascular... -
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- Altered renal expression of nitric oxide synthase isozymes in spontaneously hypertensive rats
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Kim SW, Moon KH, Lee SC, Kim NH, Kang DG, Lee JU, Choi KC, Kang YJ
- KMID: 759080
- Korean J Intern Med.
- 1999 Jan;14(1):21-26.
OBJECTIVES: The present study was aimed at exploring whether the pathogenesis of hypertension is related with an altered expression of nitric oxide synthase (NOS) isozymes, i.e., bNOS, iNOS... -
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- Insulin Like Growth Factor Binding Protein-5 Regulates Excessive Vascular Smooth Muscle Cell Proliferation in Spontaneously Hypertensive Rats via ERK 1/2 Phosphorylation
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Lee DH, Kim JE, Kang YJ
- KMID: 1429387
- Korean J Physiol Pharmacol.
- 2013 Apr;17(2):157-162.
- doi: 10.4196/kjpp.2013.17.2.157
Insulin-like growth factor binding proteins (IGFBPs) are important components of insulin growth factor (IGF) signaling pathways. One of the binding proteins, IGFBP-5, enhances the actions of IGF-1, which include the... -
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- Effects of kimchi supplementation on blood pressure and cardiac hypertrophy with varying sodium content in spontaneously hypertensive rats
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Lee SM, Cho Y, Chung HK, Shin DH, Ha WK, Lee SC, Shin MJ
- KMID: 2313610
- Nutr Res Pract.
- 2012 Aug;6(4):315-321.
We tested the effects of dietary intake of freeze-dried Korean traditional fermented cabbage (generally known as kimchi) with varying amounts of sodium on blood pressure and cardiac hypertrophy in spontaneously... -
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- Changes of CGRP- and VIP-containing Nerve Fibers in the pancreas of Streptozotocin-Induced Diabetic Rat
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Kim YJ, Won MH, Suh GG, Seong JK, Lee JS, Kim HM, Oh YS
- KMID: 2331672
- J Korean Diabetes Assoc.
- 1998 Sep;22(3):299-311.
BACKGROUND: The peptidergic nerves, namely the third nerve, are distributed in the pancreas with adreniergic and cholinergic nerves. However, it has been known that the peptidergic nerves control the pancreatic... -
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- Blood-Brain Barrier Disruption and Perivascular Beta-Amyloid Accumulation in the Brain of Aged Rats with Spontaneous Hypertension: Evaluation with Dynamic Contrast-Enhanced Magnetic Resonance Imaging
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Wang Y, Zhang R, Tao C, Xu Z, Chen W, Wang C, Song L, Zheng J, Gao F
- KMID: 2410821
- Korean J Radiol.
- 2018 Jun;19(3):498-507.
- doi: 10.3348/kjr.2018.19.3.498
OBJECTIVE: Whether blood-brain barrier (BBB) disruption induced by chronic spontaneous hypertension is associated with beta-amyloid (Aβ) accumulation in the brain remains poorly understood. The purpose of this study was to... -
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- Differentially-altered vascular guanylate cyclase isoforms in experimental hypertensive rats
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Lee JU, Kang DG, Kook H, Kim IK, Oh BS
- KMID: 1731311
- J Korean Med Sci.
- 1999 Aug;14(4):386-392.
- doi: 10.3346/jkms.1999.14.4.386
Pathophysiological implications of the vascular nitric oxide (NO)/cGMP pathway were investigated in various rat models of hypertension. The expression of brain and endothelial constitutive NO synthases (bNOS, ecNOS) was determined... -
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- Restoration of Cdk5, TrkB and Soluble N-ethylmaleimide-Sensitive Factor Attachment Protein Receptor Proteins after Chronic Methylphenidate Treatment in Spontaneous Hypertensive Rats, a Model for Attention-Deficit Hyperactivity Disorder
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Kim Y, Jeon S, Jeong HJ, Lee SM, Peña ID, Kim HJ, Han DH, Kim BN, Cheong JH
- KMID: 2454726
- Psychiatry Investig.
- 2019 Jul;16(7):558-564.
- doi: 10.30773/pi.2019.04.22
OBJECTIVE: Synaptic vesicle mobilization and neurite outgrowth regulation molecules were examined in modulation of effects of methylphenidate (MPH) in Spontaneous Hypertensive Rats (SHRs), a model for attention-deficit hyperactivity disorder (ADHD). METHODS:... -
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- Differential Expression of Proteins Related with Penile Apoptosis in a Rat after Cavernous Nerve Resection
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Yang SK, Kim B, Lee CK, Chung H, Kim HS, Ryu JK, Won KJ, Park SH, Lee HM
- KMID: 2226464
- Korean J Androl.
- 2011 Aug;29(2):111-126.
- doi: 10.5534/kja.2011.29.2.111
PURPOSE: The mechanism including changes of proteome within cavernosal tissue after cavernous nerve injury were not evaluated. We performed proteomics and functional analysis to identify proteins of penile corpus cavernosum... -
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- Proteomic Analysis of Penile Protein Alterations in a Rat Model of Cavernous Nerve Injury
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Chung H, Lee CK, Kim B, Kim HS, Kim TW, Paick SH, Jeon HS, Yang SK
- KMID: 2311850
- Korean J Urol.
- 2009 May;50(5):498-504.
PURPOSE: Cavernous nerve resection (CNR) in rats is a standard model of animal experiments on erectile dysfunction (ED) that occurs after radical prostatectomy (RP). Injured cavernous nerves after surgery can... -
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