- The tryptophan utilization concept in pregnancy
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Badawy AA
- KMID: 1841535
- Obstet Gynecol Sci.
- 2014 Jul;57(4):249-259.
- doi: 10.5468/ogs.2014.57.4.249
The decrease in maternal plasma total (free + albumin-bound) tryptophan (Trp) during the third pregnancy trimester is attributed to induction of indoleamine 2,3-dioxygenase (IDO). When measured, free [Trp] is increased... -
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- Antidiabetic Drug Metformin Protects Neuronal Cells against Quinolinic Acid-Induced Excitotoxicity by Decreasing Intracellular Calcium
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Jang S, Park SH
- KMID: 2458581
- Chonnam Med J.
- 2018 Jan;54(1):24-30.
- doi: 10.4068/cmj.2018.54.1.24
The antidiabetic drug metformin has been found to have beneficial effects in various neurological disorders; however, the molecular mechanisms underlying these effects remain unclear. Here we report that metformin protects... -
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- Differentiation of Rat Neural Stem Cells Following Transplantation in the Brain of Huntington's Disease Rat Model
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Ryu HL, Lee SY, Park K, Kim C, Jin BK, Min CK
- KMID: 2165295
- Exp Neurobiol.
- 2009 Jun;18(1):37-47.
- doi: 10.5607/en.2009.18.1.37
Stem cells provide an important means for regenerative medicine due to the capacity to generate multiple types of differentiated cells and at the same time to maintain self-renewal. To identify... -
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- A Neurodegenerative Hypothesis of Cytokine-Serotonin Interaction in Major Depression
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Kim YK
- KMID: 2341023
- J Korean Neuropsychiatr Assoc.
- 2004 Jul;43(4):386-392.
A growing body of evidence suggests that major depression is associated with increased productions of pro-inflammatory cytokines such as IL-1, IL-6, IL-12 or TNF-alpha and increased concentrations of prostaglandin E2... -
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- A Rat Model of Striatonigral Degeneration Generated by Simultaneous Injection of 6-Hydroxydopamine into the Medial Forebrain Bundle and Quinolinic Acid into the Striatum
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Yoon HH, Kim YH, Shin ES, Jeon SR
- KMID: 2069939
- J Korean Med Sci.
- 2014 Nov;29(11):1555-1561.
- doi: 10.3346/jkms.2014.29.11.1555
A double toxin-double lesion strategy is well-known to generate a rat model of striatonigral degeneration (SND) such as multiple system atrophy-parkinsonian type. However, with this model it is difficult to... -
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- Cytokines and Depression
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Kim YK
- KMID: 2029206
- Korean J Biol Psychiatry.
- 2008 Aug;15(3):175-185.
Accumulating evidence has suggested the existence of reciprocal communication between immune, endocrine, and neurotransmitter system. Cytokine hypothesis of depression implies that increased pro-inflammatory cytokine such as -1, IL-6, IL-12, TNF-alpha,... -
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