- Gastric Cancer Stem Cells: Mechanisms and Therapeutic Approaches
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Fu Y, Du P, Zhao J, Hu C, Qin Y, Huang G
- KMID: 2426328
- Yonsei Med J.
- 2018 Dec;59(10):1150-1158.
- doi: 10.3349/ymj.2018.59.10.1150
Gastric cancer (GC) is the third leading cause of cancer-related deaths worldwide. GC stem-like cells (GCSCs), with unlimited self-renewal, differentiation, and tumor-regenerating capacities, contribute significantly to the refractory features of... -
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- Complex roles of the stroma in the intrinsic resistance to gemcitabine in pancreatic cancer: where we are and where we are going
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Liang C, Shi S, Meng Q, Liang D, Ji S, Zhang B, Qin Y, Xu J, Ni Q, Yu X
- KMID: 2402943
- Exp Mol Med.
- 2017 Dec;49(12):e406.
- doi: 10.1038/emm.2017.255
Pancreatic ductal adenocarcinoma (PDAC) is among the most devastating human malignancies. The poor clinical outcome in PDAC is partly attributed to a growth-permissive tumor microenvironment. In the PDAC microenvironment, the... -
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- Kinesin superfamily member 15 knockdown inhibits cell proliferation, migration, and invasion in nasopharyngeal carcinoma
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Cai Y, Lai Q, Zhang X, Zhang Y, Zhang M, Gu S, Qin Y, Hou J, Zhao L
- KMID: 2545536
- Korean J Physiol Pharmacol.
- 2023 Sep;27(5):457-470.
- doi: 10.4196/kjpp.2023.27.5.457
The aim of this study was to investigate the role of kinesin superfamily member 15 (KIF15) in nasopharyngeal carcinogenesis (NPC) and explore its underlying mechanisms. We employed various assays, including... -
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- EGCG Blocked Phenylephrin-Induced Hypertrophy in H9C2 Cardiomyocytes, by Activating AMPK-Dependent Pathway
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Cai Y, Zhao L, Qin Y, Wu XQ
- KMID: 1791420
- Korean J Physiol Pharmacol.
- 2015 May;19(3):203-210.
- doi: 10.4196/kjpp.2015.19.3.203
AMP-activated protein kinase (AMPK) is a key regulator of energy metabolism. Previous studies have shown that activation of AMPK results in suppression of cardiac myocyte hypertrophy via inhibition of the... -
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- The Positive Association between Subclinical Hypothyroidism and Newly-Diagnosed Hypertension Is More Explicit in Female Individuals Younger than 65
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Wang X, Wang H, Yan L, Yang L, Xue Y, Yang J, Yao Y, Tang X, Tong N, Wang G, Zhang J, Wang Y, Ba J, Chen B, Du J, He L, Lai X, Li Y, Yan Z, Liao E, Liu C, Liu L, Qin G, Qin Y, Quan H, Shi B, Sun H, Ye Z, Zhang Q, Zhang L, Zhu J, Zhu M, Li Y, Teng W, Shan Z
- KMID: 2519666
- Endocrinol Metab.
- 2021 Aug;36(4):778-789.
- doi: 10.3803/EnM.2021.1101
Background: Subclinical hypothyroidism (SCH) is the most common thyroid dysfunction, and its relationship with blood pressure (BP) has been controversial. The aim of the study was to analyze the association... -
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- Urethral Pressure Measurement as a Tool for the Urodynamic Diagnosis of Detrusor Sphincter Dyssynergia
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Corona LE, Cameron AP, Clemens JQ, Qin Y, Stoffel JT
- KMID: 2431868
- Int Neurourol J.
- 2018 Dec;22(4):268-274.
- doi: 10.5213/inj.1836178.089
PURPOSE: To describe a technique for urodynamic diagnosis of detrusor sphincter dyssynergia (DSD) using urethral pressure measurements and examine potential associations between urethral pressure and bladder physiology among patients with... -
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- Distribution of pathological types and epidemiological characteristics based on kidney biopsy in Northwest China
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Qin Y, Zhao J, Wei X, Wang Y, Yu Z, Zhang Y, Sun S
- KMID: 2540183
- Kidney Res Clin Pract.
- 2023 Jan;42(1):63-74.
- doi: 10.23876/j.krcp.21.296
Background: The spectrum of biopsy-confirmed kidney disease varies with regions and periods. We describe the distribution of pathological types and epidemiological characteristics of kidney diseases in Northwest China due to... -
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- Predictive Value of Exercise Blood Pressure Changes for Orthostatic Hypotension in Patients With Parkinson’s Disease
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Qin Y, Jin Zh, Zhang Zy, Chen Kk, Yu X, Yan Hj, Wang Rd, Su Y, Liu Ax, Xi Jn, Fang By
- KMID: 2537186
- J Clin Neurol.
- 2023 Jan;19(1):67-75.
- doi: 10.3988/jcn.2023.19.1.67
Background and Purpose Orthostatic hypotension (OH) is common in patients with Parkinson’s disease (PD). Early recognition OH is required with sensitive assessments. The purpose of this study was to determine... -
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- β-Sitosterol treatment attenuates cognitive deficits and prevents amyloid plaque deposition in amyloid protein precursor/presenilin 1 mice
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Ye JY, Li L, Hao QM, Qin Y, Ma CS
- KMID: 2466568
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):39-46.
- doi: 10.4196/kjpp.2020.24.1.39
Alzheimer's disease (AD) is the most common neurodegenerative disorder causing dementia worldwide, and is mainly characterized by aggregated β-amyloid (Aβ). Increasing evidence has shown that plant extracts have the potential... -
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- Efficacy and Safety of Pulse Magnetic Therapy System in Insomnia Disorder: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial
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Liao J, Wang S, Zhou B, Liang W, Ma P, Lin M, Lin W, Li C, Zhang X, Li H, Cui Y, Hu J, Qin Y, Deng Y, Fu A, Zhu T, Zhang S, Qu Y, Xing L, Li W, Feng F, Yao X, Zhang G, Pan J
- KMID: 2543114
- Psychiatry Investig.
- 2023 Jun;20(6):559-566.
- doi: 10.30773/pi.2022.0362
Objective This study’s objective is to assess the efficacy and safety of Pulsed Magnetic Therapy System (PMTS) in improving insomnia disorder. Methods Participants with insomnia disorder were randomly assigned to receive... -
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- Feasibility of a Clinical-Radiomics Model to Predict the Outcomes of Acute Ischemic Stroke
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Zhou Y, Wu D, Yan S, Xie Y, Zhang S, Lv W, Qin Y, Liu Y, Liu C, Lu J, Li J, Zhu H, Liu WV, Liu H, Zhang G, Zhu W
- KMID: 2532203
- Korean J Radiol.
- 2022 Aug;23(8):811-820.
- doi: 10.3348/kjr.2022.0160
Objective: To develop a model incorporating radiomic features and clinical factors to accurately predict acute ischemic stroke (AIS) outcomes. Materials and Methods: Data from 522 AIS patients (382 male [73.2%]; mean... -
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