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Neuromuscular Block by Vecuronium and its Reversal with Pyridostigmine in Rabbits

Kim KH, Lee DH, Kim KS, Suh JK, Yoo HK, Seung IS, Chon SU

Despite the fact that the anticholinesterases, mainly neostigmine, has been used for many years to antagonize a nondepolarizing neuromuscular blockade, until recently nothing was known about their pharmacokinetics and dynamics...
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Growth hormone response to L-dopa and pyridostigmine in women with polycystic ovary syndrome

Lee KM, Lee EJ, Kim KR, Lee BS, Park KH, Bae HD, Chung YS, Lim SK, Lee HC, Huh KB

  • KMID: 1686872
  • J Korean Soc Endocrinol.
  • 1993 Sep;8(3):265-272.
No abstract available.
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Treatment of Dysphagia with Pyridostigmine Bromide in a Patient with the Pharyngeal-Cervical-Brachial Variant of Guillain-Barre Syndrome

Lee KL, Lim OK, Lee JK, Park KD

A 24-year-old male developed bulbar palsy, ophthalmoplegia, ptosis, and shoulder weakness bilaterally 2 weeks after he had experienced an upper respiratory infection. The electrodiagnostic study demonstrated axonal polyradiculoneuropathy. The repetitive...
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The Relationships between Administration Time of Pyridostigmine and the Recovery of Vecuronium-induced Neuromuscular Blockade

Kim CS, Shin JH, Han CS, Kim IH, Kim SY

BACKGROUND: The timing of administration may be an important factor in order to obtain maximal antagonizing effect of anticholinesterase on neuromuscular blockade. The objective of this study is to seek for...
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Myasthenia Gravis Appearing After Thymectomy: a Case Report and Review of the Literature

Kang SY, Lee JS, Choi JC, Kang JH

A small proportion of thymoma patients without myasthenia gravis (MG) have been observed to develop MG after total removal of the thymoma. However, the underlying cause is not yet known...
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The Effects of Pyridostigmine and Levosulpiride on the Contraction of Rabbit Urinary Bladders

Ko YH, Lee JG

  • KMID: 2293758
  • Korean J Urol.
  • 2003 Feb;44(2):180-185.
PURPOSE: This study was performed to identify the effects of bethanechol, pyridostigmine and levosulpiride, on the contraction of rabbit bladder strip tissue in a single agent administration, and to investigate...
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Response to neuromuscular blockade with rocuronium during general anesthesia in a patient with dermatomyositis: A case report

Kim SY, Lee YB

Dermatomyositis is an idiopathic inflammatory myopathy characterized by skin changes and muscle weakness. Depending on the involvement of various muscles, dermatomyositis can cause aspiration pneumonia, ventilatory impairment, and heart failure....
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Comparative Study on Neostigmine and Pyridostigmine during Vecuronium Reversal in Rabbits

Kim DW, Kim KH, Lee DH, Kim KS, Suh JK, Yoo HK, Seung IS, Chon SU

Anesthesiologists may have close relationship with muscle relaxants in clinical practice. Fourtunately, a few of the new muscle relaxants were discovered and used in clinic recently. Newly introduced non-depolarizing muscle...
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A Case with Ophthalmoplegia Following Snake Bite

Min JH, Do HS, Hong SW, Han SK, Kim IS, Ryu S, Kim SW, Yoo IS

  • KMID: 2331478
  • J Korean Soc Emerg Med.
  • 2006 Oct;17(5):509-511.
Ophthalmoplegia following snake bite is a rare but not serious neurotoxic complication. However, symptoms like diplopia, blurred vision, and ocular discomfort can be emotionally devastating for a patient. We experienced...
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Effect of neuromuscular blockade reversal by pyridostigmine on spectral entropy values during recovery from desflurane anesthesia: a prospective, randomized, double-blind, controlled trial

Kim E, Ryu JH, Byun SH

BACKGROUND: According to several studies investigating the relationship between muscle activity and electroencephalogram results, reversal of neuromuscular blockade (NMB) may affect depth of anesthesia indices. Therefore, we investigated the effect...
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Antagonism of Vecuronium - Induced Profound Meuromuscular Blockade with Early Administration of Neostigmine or Pyridostigmine

Kim JU, Lee IO, Yoon SM

To compare the time course of neostigmine and pyridostigmine antagonism of profound neu- romuscular blockade (no-twitch: when no response to peripheral nerve stimulation could be elicited) induced by vecuronium,...
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House-Hold Myasthenic Syndrome

Han DK, Choi SK, SONG JE

  • KMID: 1675875
  • J Korean Ophthalmol Soc.
  • 1967 Dec;8(3):31-36.
We have recently seen a myasthenic syndrome occurring in a mother, four out of five children, a young woman of non-blood relative. All developed this disease between April and June,...
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Effects of Neostigmine and Pyridostigmine on the Cardiovascular Responses in Inhalation Anesthesia

Kang HS, Lee GY, Lee CH

At the end of the operation, residual neuromusular blookade may be antagonized by anticholines-terase (edrophonium, neostigmine and pyridostigmine). Neostigmine is probably commonly used antagonist of nondepolarizing neuromuscular blocking agents. But,...
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Pyridostigmine for Treatment of Acute Colonic Pseudo-obstruction(Ogilvie's syndrome) in a Older Patient on CAPD

Choi JH, Nam YH, Seo IS, Lim JW, Jang YH, Kim BR, Yoon SJ, Kim HC

  • KMID: 2338705
  • J Korean Geriatr Soc.
  • 2007 Sep;11(3):162-166.
In acute colonic pseudo-obstruction(Ogilvie's syndrome, 1948), there is no distal obstruction but colonic obstruction symptom and distended colon is shown radiologicaly and clinically. The etiology of this syndrome are complex...
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Comparison of sugammadex and pyridostigmine bromide for reversal of rocuronium-induced neuromuscular blockade in short-term pediatric surgery: a prospective randomized study

An J, Kim E, Lee J, Kim H, Son J, Huh J, Woo K

BACKGROUND: Sugammadex reverses rocuronium-induced neuromuscular blockade quickly and effectively. Herein, we compared the efficacy of sugammadex and pyridostigmine in the reversal of rocuronium-induced light block or minimal block in pediatric...
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Postoperative Residual Curarization either after Continuous Infusions or Intermittent Bolus of Rocuronium or Vecuronium

Kang SY, Chung RK, Lee CH

BACKGROUND: Although the incidence of postoperative residual curarization (PORC) following the use of intermediate-acting neuromuscular blocking agents is lower than that of longer-acting neuromuscular blocking agents, it has been reported...
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Cardiac arrest following reversal of muscle relaxation by pyridostigmine: A case report

Jo JY, Yi JM, Lee YK, Ku SW, Park PH

  • KMID: 1908529
  • Anesth Pain Med.
  • 2014 Jul;9(3):205-208.
The anticholinesterase pyridostigmine is usually used as a reversal agent of non-depolarizing muscle relaxants in general anesthesia. Most adverse muscarinic effects of anticholinesterases are controlled by anticholinergics; however, there is...
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Prolonged Neuromuscular Blockade Following Succinycholine Administration in a Patient with Plasma Cholinestrase Variant

Cho CH, Baik HJ, Kim KS, Oh DJ

The authors experienced a case of plasma cholinesterase variant who received succinylcholine, atracurium and reversal with pyridostigmine, and showed prolonged neuromuscular blockade postoperatively, and was ventilated artificia1ly until complete recovery....
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Total intravenous anesthesia in a 10-month-old patient with congenital myotonic dystrophy undergoing endoscopic third ventriculostomy: A case report

Joh JH, Kim JY, Baek SH, Song JG, Lee YM, Kim JU

Myotonic dystrophy is a rare genetic disorder characterized by muscle atrophy and weakness. Surgical treatment of this condition poses various problems for the anesthesiologist. We describe the anesthetic management of...
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Mechanism of Impaired Growth Hormone Response in Children with Simple Obesity

Park MS, Park MJ, Kim HS, Kim DH

  • KMID: 2335101
  • J Korean Pediatr Soc.
  • 1994 Apr;37(4):457-463.
Obesity is associated with an impairment of the growth hormone secretion elicited by all stimuli known to date, but the basic mechanism of the alteration is unknown to date, but...
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