- Optimal Concentration of Thrombin to Activate Platelet for Wound Healing
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Eum SJ, Han SK, Chun KW, Kim WK
- KMID: 2203118
- J Korean Soc Plast Reconstr Surg.
- 2009 Jan;36(1):19-23.
PURPOSE: Platelet transplantation is a novel therapeutic strategy for acceleration of wound healing. When applying platelets, efficacy of adding thrombin to stimulate growth factor release from platelets has already been... -
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- Olibanum Extract Inhibits Vascular Smooth Muscle Cell Migration and Proliferation in Response to Platelet-Derived Growth Factor
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Choi OB, Park JH, Lee YJ, Lee CK, Won KJ, Kim J, Lee HM, Kim B
- KMID: 2071659
- Korean J Physiol Pharmacol.
- 2009 Apr;13(2):107-113.
- doi: 10.4196/kjpp.2009.13.2.107
Olibanum (Boswellia serrata) has been shown to have anti-inflammatory, anti-arthritic and anti- cancer effects. This study determined the role of a water extract of olibanum in platelet-derived growth factor (PDGF)-stimulated... -
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- Increased Growth Factors in Children with Mycoplasma pneumoniae Pneumonia
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Lee HJ, Kim JY, Park HJ, Kim WT, Kim JK, Choi EJ, Lee KH, Lee KH, Chung HL
- KMID: 2315014
- Pediatr Allergy Respir Dis.
- 2010 Mar;20(1):41-47.
PURPOSE: Mycoplasma pneumoniae is a common causative agent of community acquired pneumonia in children and is well known to cause various respiratory and extrapulmonary diseases. We determined whether growth factors,... -
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- Dermatofibrosarcoma Protuberans: A Study of Clinical, Pathologic, Genetic, and Therapeutic Features in Korean Patients
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Zheng Z, Piao J, Lee JH, Kim SE, Kim SC, Chung KY, Roh MR
- KMID: 2070022
- Yonsei Med J.
- 2015 Mar;56(2):440-446.
- doi: 10.3349/ymj.2015.56.2.440
PURPOSE: Dermatofibrosarcoma protuberans (DFSP) carries a translocation resulting in the collagen type I alpha 1 (COL1A1)-platelet-derived growth factor beta (PDGFB) fusion gene, which is responsible for PDGFB activation. The purpose... -
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- miR-379 Inhibits Cell Proliferation, Invasion, and Migration of Vascular Smooth Muscle Cells by Targeting Insulin-Like Factor-1
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Li K, Wang Y, Zhang A, Liu B, Jia L
- KMID: 2374211
- Yonsei Med J.
- 2017 Jan;58(1):234-240.
- doi: 10.3349/ymj.2017.58.1.234
PURPOSE: MicroRNAs are small non-coding RNAs that play important roles in vascular smooth muscle cell (VSMC) function. This study investigated the role of miR-379 on proliferation, invasion, and migration of... -
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- Platelet-Rich Plasma: Quantitative Assessment of Growth Factor Levels and Comparative Analysis of Activated and Inactivated Groups
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Lee JW, Kwon OH, Kim TK, Cho YK, Choi KY, Chung HY, Cho BC, Yang JD, Shin JH
- KMID: 2120808
- Arch Plast Surg.
- 2013 Sep;40(5):530-535.
- doi: 10.5999/aps.2013.40.5.530
BACKGROUND: Platelet-rich plasma (PRP) has more concentrated platelets than normal plasma (approximately 150-400x10(3) cell/dL). Platelets excrete several growth factors and cytokines that are associated with the healing and regeneration process.... -
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- Tetrahydrobiopterin Inhibits PDGF-stimulated Migration and Proliferation in Rat Aortic Smooth Muscle Cells via the Nitric Oxide Synthase-independent Pathway
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Jiang X, Kim B, Lin H, Lee CK, Kim J, Kang H, Lee P, Jung SH, Lee HM, Won KJ
- KMID: 2285400
- Korean J Physiol Pharmacol.
- 2010 Jun;14(3):177-183.
- doi: 10.4196/kjpp.2010.14.3.177
Tetrahydrobiopterin (BH4), an essential cofactor for nitric oxide synthase (NOS) activity, is known to play important roles in modulating both NO and superoxide production during vascular diseases such as atherosclerosis.... -
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- Effect of RHPDGF-BB and RhBMP-2 on Osseointegration of Titanium Implants at Periimplant Bone Defects Grafted with Hydroxyapatite: Micro-Ct and Histologic Analysis
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Park JH, Hwang SJ, Kim MJ
- KMID: 1474263
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2009 Nov;31(6):461-468.
PURPOSE: Platelet derived growth factor(PDGF)-BB and bone morphogenetic protein(BMP)-2 are wellknown representative growth factors. The purposes of this study were to investigate the effect of rhPDGFBB and rhBMP-2 on osseointegration... -
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- Scoparone interferes with STAT3-induced proliferation of vascular smooth muscle cells
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Park S, Kim JK, Oh CJ, Choi SH, Jeon JH, Lee IK
- KMID: 2155410
- Exp Mol Med.
- 2015 Mar;47(3):e145.
- doi: 10.1038/emm.2014.113
Scoparone, which is a major constituent of Artemisia capillaries, has been identified as an anticoagulant, hypolipidemic, vasorelaxant, anti-oxidant and anti-inflammatory drug, and it is used for the traditional treatment of... -
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- Effects of the immobilization of heparin and rhPDGF-BB to titanium surfaces for the enhancement of osteoblastic functions and anti-inflammation
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Huh JB, Lee JY, Lee KL, Kim SE, Yun MJ, Shim JS, Shim JS, Shin SW
- KMID: 2118125
- J Adv Prosthodont.
- 2011 Sep;3(3):152-160.
- doi: 10.4047/jap.2011.3.3.152
PURPOSE: This study was to investigate the effects of recombinant human platelet-derived growth factor (rhPDGF-BB) and heparin to titanium surfaces for enhancement of osteoblastic functions and inhibition of inflammation activity. MATERIALS... -
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- Loss of Heterozygosity Studies on Chromosome 9, 22 and 17p in 12 Various Pediatric Brain Tumors
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Jung HL, Lau CC
- KMID: 1535334
- Korean J Pediatr Hematol Oncol.
- 1998 Oct;5(2):293-303.
PURPOSE: The normal function of tumor suppressor genes is thought to be related to their ability to regulate cell proliferation and the loss of such function presumably leads to malignant... -
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- Enhanced skin wound healing by a sustained release of growth factors contained in platelet-rich plasma
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Yang HS, Shin J, Bhang SH, Shin JY, Park J, Im GI, Kim CS, Kim BS
- KMID: 1025165
- Exp Mol Med.
- 2011 Nov;43(11):622-629.
- doi: 10.3858/emm.2011.43.11.070
Platelet-rich plasma (PRP) contains growth factors that promote tissue regeneration. Previously, we showed that heparin-conjugated fibrin (HCF) exerts the sustained release of growth factors with affinity for heparin. Here, we... -
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