- Immunohistochemical and SSCP analysis of p53 in malignant lymphomas
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Park CK, Lee JD
- KMID: 1038162
- J Korean Med Sci.
- 1998 Aug;13(4):361-368.
- doi: 10.3346/jkms.1998.13.4.361
We immunohistochemically investigated Epstein-Barr virus (EBV)-positive and negative 31 malignant lymphomas (MLs) for p53 protein using a monoclonal antibody which is expressed on a wild type and mutant human... -
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- Oncogene interaction in basal cell carcinomas of human skin
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Ro YS
- KMID: 644859
- J Korean Med Sci.
- 1995 Apr;10(2):85-92.
- doi: 10.3346/jkms.1995.10.2.85
The expression of the p53 protein (p53) was compared with those of several oncogenes including c-fos (Fos), c-jun (Jun), and epidermal growth factor receptor (EGFR1) using immunohistochemistry in frozen and... -
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- Diagnostic p53 expression in gastric endoscopic mucosal resection
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Cho JH, Roe IH, Jin YJ
- KMID: 1731315
- J Korean Med Sci.
- 1999 Aug;14(4):412-416.
- doi: 10.3346/jkms.1999.14.4.412
Endoscopic mucosal resection (EMR) has been standardized for the treatment of intestinal type of intramucosal gastric carcinomas, and careful histological examination of the resected specimen is important for further treatment.... -
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- Human Papillomavirus 16/18 Expression of Endocervical Glandular Lesions: Relationship with p53 and MIB-1 Expressions
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Yoon HK, Kim YJ, Kang MS
- KMID: 648252
- J Korean Med Sci.
- 2001 Apr;16(2):169-174.
- doi: 10.3346/jkms.2001.16.2.169
The pathogenesis of endocervical glandular lesions are not clearly understood. The aims of this study are to evaluate the etiologic role of human papillomavirus (HPV) 16/18 and the relationship of... -
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- p53 Mutation and Epidermal Growth Factor Receptor Overexpression in Glioblastoma
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Yoon KS, Lee MC, Kang SS, Kim JH, Jung S, Kim YJ, Lee JH, Ahn KY, Lee JS, Cheon JY
- KMID: 648308
- J Korean Med Sci.
- 2001 Aug;16(4):481-488.
- doi: 10.3346/jkms.2001.16.4.481
Recent molecular studies indicate two different genetic pathways leading to the development of glioblastoma; final progression of astrocytoma and de novo formation. To define the mutual relationships of cytogenetic changes... -
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- The Role of Estrogen Receptor, Progesterone Receptor and p53 in Development of Stress Urinary Incontinence
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Bai SW, Jung YW, Kwon HS, Yoon JM, Shin JS, Kim SK, Park KH, Park JH
- KMID: 1103912
- Yonsei Med J.
- 2004 Oct;45(5):885-890.
- doi: 10.3349/ymj.2004.45.5.885
Recent studies have been reported the roles of the estrogen receptor (ER), progesterone receptor (PR) and p53 in the development of a pelvic organ prolapse (POP). The pathogenesis of stress... -
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- Apoptosis of Skeletal Muscle on Steroid-Induced Myopathy in Rats
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Lee MJ, Lee JS, Lee MC
- KMID: 648306
- J Korean Med Sci.
- 2001 Aug;16(4):467-474.
- doi: 10.3346/jkms.2001.16.4.467
Recently apoptotic cell death has been reported in differentiated skeletal muscle, where apoptosis was generally assumed not to occur. To investigate whether apoptosis may contribute to the steroid-induced myopathy, rats... -
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- Immunohistochemical Detection of p53 Expression in Patients with Preoperative Chemoradiation for Rectal Cancer: Association with Prognosis
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Huh JW, Lee WY, Kim SH, Park YA, Cho YB, Yun SH, Kim HC, Park HC, Choi DH, Park JO, Park YS, Chun HK
- KMID: 2352792
- Yonsei Med J.
- 2015 Jan;56(1):82-88.
- doi: 10.3349/ymj.2015.56.1.82
PURPOSE: The expression of p53 in patients with rectal cancer who underwent preoperative chemoradiationand and its potential prognostic significance were evaluated. MATERIALS AND METHODS: p53 expression was examined using immunohistochemistry in... -
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- Prognostic Value of Immunohistochemical Staining of p53, bcl-2, and Ki-67 in Small Cell Lung Cancer
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Paik KH, Park YH, Ryoo BY, Yang SH, Lee JC, Kim CH, Ki SS, Kim JM, Park MJ, Ahn HJ, Choi W, Chung JH
- KMID: 2157779
- J Korean Med Sci.
- 2006 Feb;21(1):35-39.
- doi: 10.3346/jkms.2006.21.1.35
Small cell lung cancer (SCLC) is one of the most fatal cancers in humans and many factors are known to be related to its poor prognosis. Immunohistochemical (IHC) stainings were... -
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- P53 overexpression in gastric adenocarcinoma with Helicobacter pylori infection
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Chang KH, Kwon JW, Kim BS, Hwang JH, Lee SK, Lee YC, Park HJ, Park IS, Kim HK
- KMID: 699939
- Yonsei Med J.
- 1997 Apr;38(2):117-124.
- doi: 10.3349/ymj.1997.38.2.117
Gastric carcinogenesis has been studied in various aspects. Helicobacter pylori (Hp) infection and mutation of the p53 tumor suppressor gene have recently been argued to be important factors... -
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- Papillary Immature Metaplasia of the Uterine Cervix: a Report of 5 Cases with an Emphasis on the Differential Diagnosis from Reactive Squamous Metaplasia, High-Grade Squamous Intraepithelial Lesion and Papillary Squamous Cell Carcinoma
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Kang GH, Min K, Shim YH, Kim KR
- KMID: 648359
- J Korean Med Sci.
- 2001 Dec;16(6):762-768.
- doi: 10.3346/jkms.2001.16.6.762
Papillary immature metaplasia (PIM) is a distinctive exophytic lesion of the uterine cervix and shares some histologic and cytologic features with ordinary squamous metaplasia (SM), atypical immature squamous metaplasia (AIM),... -
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- Effect of Helicobacter pylori on Gastric Epithelial Cell Kinetics and Expression of Apoptosis-related Proteins in Gastric Carcinogenesis
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Lee KM, Lee DS, Yang JM, Ahn BM, Lee EH, Yoo JY, Kim YJ, Chung IS, Sun HS, Park DH
- KMID: 772516
- Korean J Gastroenterol.
- 2003 Jul;42(1):12-19.
BACKGROUND/AIMS: We investigated apoptosis, cell proliferation and the expression of apoptosis-related proteins in the gastric epithelial cells of Helicobacter pylori (H. pylori)-negative and positive patients. METHODS: TUNEL staining, immunohistochemical... -
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- Canine biphasic synovial sarcoma: case report and immunohistochemical characterization
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Loukopoulos P, Heng HG, Arshad H
- KMID: 1120075
- J Vet Sci.
- 2004 Jun;5(2):173-180.
The clinical, radiological and pathologic features of a biphasic synovial sarcoma in the left elbow joint of a two-year-old male Rottweiler are presented. The tumor showed positive immunoreactivity for vimentin,... -
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- The Expression of Multiple Proteins as Prognostic Factors in Colorectal Cancer: Cathepsin D, p53, COX-2, Epidermal Growth Factor Receptor, C-erbB-2, and Ki-67
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Shin IY, Sung NY, Lee YS, Kwon TS, Si Y, Lee YS, Oh ST, Lee IK
- KMID: 1774523
- Gut Liver.
- 2014 Jan;8(1):13-23.
BACKGROUND/AIMS: A single gene mutation alone cannot explain the poor prognosis of colorectal cancer. This study aimed to establish a correlation between the expression of six proteins and the prognosis... -
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- Colorectal adenocarcinoma as a second malignant neoplasm following rhabdomyosarcoma of the urinary bladder: a case report
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Park SS, Kim BK, Kim CJ, Kim WS, Kim IO, Park KW, Shin HY, Ahn HS
- KMID: 1730650
- J Korean Med Sci.
- 2000 Aug;15(4):475-477.
- doi: 10.3346/jkms.2000.15.4.475
Following improvements in therapy for childhood malignancies, the striking increase in survival rate over the past 30 years has led to the increase risk of developing second malignant neoplasms (SMNs).... -
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- Involvement of mitogen-activated protein kinases and p21Waf1 in hydroxyurea-induced G1 arrest and senescence of McA-RH7777 rat hepatoma cell line
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Hong SH, Hong BS, Kim DC, Rho MS, Park JI, Rha SH, Jun HS, Jeong JS
- KMID: 1123771
- Exp Mol Med.
- 2004 Oct;36(5):493-498.
Hydroxyurea is commonly used to treat hematologic disorders and some type of solid tumors, but the mechanism for its therapeutic effect is not clearly known. In this study, we examined... -
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- Significance of Microsatellite Instability in Early Gastric Cancer Treated by Endoscopic Submucosal Dissection
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Kim KM, Kim YS, Cho JY, Jung IS, Kim WJ, Choi IS, Ryu CB, Kim JO, Lee JS, Jin SY, Shim CS, Kim BS
- KMID: 1112575
- Korean J Gastroenterol.
- 2008 Mar;51(3):167-173.
BACKGROUND/AIMS: Microsatellite instability (MSI) is defined as a change of any length due to either insertion or deletion of repeating units, in a microsatellite within a tumor when compared to... -
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- Expression of biliary antigen and its clinical significance in hepatocellular carcinoma
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Yoon DS, Jeong J, Park YN, Kim KS, Kwon SW, Chi HS, Park C, Kim BR
- KMID: 711681
- Yonsei Med J.
- 1999 Oct;40(5):472-477.
- doi: 10.3349/ymj.1999.40.5.472
In order to classify the hepatocellular carcinomas (HCCs) which had diverse clinicopathologic characteristics, we divided HCCs into two groups according to the expression of biliary antigen on the basis of... -
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