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Sedative Effect of Sophora flavescens and Matrine

Lee HJ, Lee SY, Jang D, Chung SY, Shim I

The present study investigated the sedative effects of Sophora flavescens (SF) and its bioactive compound, matrine through performing locomotor activity test and the electroencephalography (EEG) analysis in the rat. The...
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A role for endocannabinoids in acute stress-induced suppression of the hypothalamic-pituitary-gonadal axis in male rats

Karamikheirabad M, Behzadi G, Faghihi M, Raoofian R, Ejtemaei Mehr S, Zuure WA, Sadeghipour HR

OBJECTIVE: Stress is known to be an inhibitor of the reproductive hypothalamic-pituitary-gonadal (HPG) axis. However, the neural and molecular connections between stress and reproduction are not yet understood. It is...
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Somatostatin Inhibits Gonadotropin Releasing Hormone Neuronal Activities in Juvenile Mice

Park SA, Bhattarai , Han SK

BACKGROUND: The gonadotropin releasing hormone (GnRH) neurons perform a pivotal function in the central regulation of fertility. Somatostatin (SST) is an important neuromodulatory peptide in the central nervous system and...
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Normal Sleep in Children and Adolescents

Nam SO

  • KMID: 1442105
  • J Korean Child Neurol Soc.
  • 2011 Aug;19(2):67-75.
Sleep is not just a rest for brain activity during daytime, but also has a vital function for memory consolidation after learning as well as restoration of both body and...
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Age-dependent Kisspeptin Effects on the GnRH Neurons in Male and Female Mice

Bhattarai , Park SA, Yin H, Park SJ, Jeon JG, Chang KW, Lee SY, Ryu PD, Han SK

BACKGROUND: The gonadotropin releasing hormone (GnRH) neurons play a pivotal role in the central regulation of fertility. Kisspeptin binds to the G-protein coupled receptor 54 (GPR54) and GPR54 has been...
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Neuroanatomy of Sleep-Wake Regulation and its Application to Pharmacotherapy

Kim HC

  • KMID: 2286720
  • Korean J Psychopharmacol.
  • 2007 May;18(3):133-142.
A current hypothesis of sleep-wake regulation proposes that the sleep process starts with the activation of sleep-promoting neurons located in the preoptic area of the anterior hypothalamus. This activation leads...
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A case of fever of unknown origin after removal of hypothalamic tumor

Park JH, Yu HS, Go JS, Bae WG, Shin J, Kim SJ, Shin DH

  • KMID: 2252776
  • Korean J Med.
  • 2003 Nov;65(Suppl 3):S894-S897.
The preoptic area and anterior hypothalamus plays a pivotal role in body temperature regulation, and damage in this region causes hyperthermia. This hyperthermia is particularly troublesome because of the possibility...
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Effect of serotonin uptake inhibitors on serotonin metabolism in the hypothalamus of freely moving rats

Song YS, Yoon SN, Jung DS, Yoo SH, Ryu HK, Kim HG

  • KMID: 1581021
  • Korean J Physiol Pharmacol.
  • 2000 Dec;4(6):439-444.
Tricyclic antidepressant clomipramine or selective serotonin reuptake inhibitors (SSRIs) have been commonly used for the treatment of premature ejaculation. In the present study, we analyzed the concentrations of serotonin and 5-hydroxyindoleacetic acid (5-HIAA)...
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Change of Serotonin Concentraions in Rat Medial Preoptic Area of Hypothalmus by Clomipramine and Various Selective Serotonin Reuptake Inhibitors

Song YS, Kim ME, Park YH, Kim HG

  • KMID: 1583109
  • Korean J Urol.
  • 2000 May;41(5):659-666.
No abstract available.
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A Case of Kallmann's Syndrome with Hypoplasia of Olfactory Bulb

Nam YS, Lee SH, Han SY, Yoon TK, Cha KY

  • KMID: 2235742
  • Korean J Fertil Steril.
  • 1999 Aug;26(2):281-285.
Kallmann's syndrome has both a general and specific connotation in describing general condition of gonadotropin-releasing hormone (GnRH) deficiency or a particular cluster of anomalies associated with primary eunuchoidism. The familial...
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Comparative effects on secretion of LH, FSH, prolactin, and testosterone by chronic and direct hypothalamic administration of nonylphenol to adult male rats

Park KS, Jang WC, Kim MK, Kim HG

  • KMID: 1554146
  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):215-222.
Nonylphenol (NP) is a widespread environmental pollutant that has been shown to exert both toxic and estrogenic effects on mammalian cells. As the effects of NP on the reproductive system of adult...
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Coexistence of Tyrosine Hydroxylase and Nicotinamide Adenine Dinucleotide Phosphate-Diaphorase in Hypothalamic Neurons of the Rat

Huh YB, Cho JS, Song CS, Ahn HK

  • KMID: 2092646
  • Korean J Anat.
  • 1998 Feb;31(1):119-126.
The presence and coexistence of nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-diaphorase) with tyrosine hydroxylase (TH) was investigated by combining NADPH-diaphorase histochemistry with TH immunohistochemistry in hypothalamic nuclei of the rat. TH-immunoreactive...
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Dopaminergic Neurons in the Diencephalon of Striped Field Mouse[Apodemus agrarius coreae]

Jung YG, Lee NS, Min SH, Kim MG

  • KMID: 2224602
  • Korean J Anat.
  • 1997 Dec;30(6):609-622.
The distributions and morphological characteristics of neurons displaying immunoreactivity to the catecholamine synthetic enzymes, tyrosine hydroxylase[TH], dopamine-beta-hydroxylase[DBH], and phenyletha-nolamine-N-methyltransferase[PNMT] were examined in the adjacent sections of the diencephalon of the...
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Central Neural Pathway for the Rat Tongue

Kim MO, Lee BH, Choi WS, Jo GJ, Seo SJ, Kim CH

  • KMID: 2224618
  • Korean J Anat.
  • 1997 Aug;30(4):375-388.
Bartha strain of pseudorabies virus[PRV-Ba] was utilized as a tracer to identify the neuronal axis of rat tongue muscles ; intrinsic muscles and extrinsic muscles, styloglossus, genioglossus, and hyoglossus muscle....
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The Effects of Gonadectomy and Prenatal Testosterone Injection on Galanin Immunoreactive Cells in the Medial Preoptic Area of Rats

Park IS, Kim JT

  • KMID: 1529462
  • Korean J Anat.
  • 1997 Jun;30(3):259-268.
Within the medial preoptic area[MPOA], several cytoarchitectonically defined cell groups are sexually dimorphic in their morphology. Specially, the sexual dimorphic nucleus of the preoptic area[SDN-POA] is reported an example of...
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