- Stem Cell Properties of Therapeutic Potential
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Seo GS
- KMID: 1018399
- Korean J Gastroenterol.
- 2011 Sep;58(3):125-132.
- doi: 10.4166/kjg.2011.58.3.125
Stem cell research is a innovative technology that focuses on using undifferentiated cells able to self-renew through the asymmetrical or symmetrical divisions. Three types of stem cells have been studied... -
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- Very small embryonic-like stem-cell optimization of isolation protocols: an update of molecular signatures and a review of current in vivo applications
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Shin DM, Suszynska , Mierzejewska K, Ratajczak , Ratajczak
- KMID: 2154275
- Exp Mol Med.
- 2013 Nov;45(11):e56.
As the theory of stem cell plasticity was first proposed, we have explored an alternative hypothesis for this phenomenon: namely that adult bone marrow (BM) and umbilical cord blood (UCB)... -
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- Efficient culture system for human embryonic stem cells using autologous human embryonic stem cell-derived feeder cells
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Yoo SJ, Yoon BS, Kim JM, Song JM, Roh SI, You S, Yoon HS
- KMID: 1089449
- Exp Mol Med.
- 2005 Oct;37(5):399-407.
Human embryonic stem cells (hESCs) need feeder cells for their maintenance in an undifferentiated state. In conventional culture systems, mouse embryonic fibroblasts (MEFs) serve as feeder cells to maintain hESCs.... -
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- Implications and limitations of cellular reprogramming for psychiatric drug development
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Tobe BT, Brandel MG, Nye JS, Snyder EY
- KMID: 2154278
- Exp Mol Med.
- 2013 Nov;45(11):e59.
Human-induced pluripotent stem cells (hiPSCs) derived from somatic cells of patients have opened possibilities for in vitro modeling of the physiology of neural (and other) cells in psychiatric disease states.... -
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- Disease-specific induced pluripotent stem cells: a platform for human disease modeling and drug discovery
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Jang J, Yoo JE, Lee JA, Lee DR, Kim JY, Huh YJ, Kim DS, Park CY, Hwang DY, Kim HS, Kang HC, Kim DW
- KMID: 1245263
- Exp Mol Med.
- 2012 Mar;44(3):202-213.
- doi: 10.3858/emm.2012.44.3.015
The generation of disease-specific induced pluripotent stem cell (iPSC) lines from patients with incurable diseases is a promising approach for studying disease mechanisms and drug screening. Such innovation enables to... -
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- Reactive oxygen species enhance differentiation of human embryonic stem cells into mesendodermal lineage
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Ji AR, Ku SY, Cho MS, Kim YY, Kim YJ, Oh SK, Kim SH, Moon SY, Choi YM
- KMID: 946650
- Exp Mol Med.
- 2010 Mar;42(3):175-186.
- doi: 10.3858/emm.2010.42.3.018
Recently, reactive oxygen species (ROS) have been studied as a regulator of differentiation into specific cell types in embryonic stem cells (ESCs). However, ROS role in human ESCs (hESCs) is... -
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- Use of Long-term Cultured Embryoid Bodies May Enhance Cardiomyocyte Differentiation by BMP2
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Kim YY, Ku SY, Jang J, Oh SK, Kim HS, Kim SH, Choi YM, Moon SY
- KMID: 2158201
- Yonsei Med J.
- 2008 Oct;49(5):819-827.
- doi: 10.3349/ymj.2008.49.5.819
PURPOSE: Human embryonic stem cells (hESCs) can proliferate for a prolonged period and differentiate into cardiomyocytes in vitro. Recent studies used bone morphogenetic protein 2 (BMP2) to generate cardiomyocytes from... -
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