- Characterization of Heparin:PF4 Isoantibody Interaction to Platelets in Heparin-Induced Thrombocytopenia/ Thrombosis
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Kim KY, Chang YJ, Suh JS, Kim JS
- KMID: 2146196
- Korean J Clin Pathol.
- 1997 Dec;17(6):944-955.
BACKGROUND: Heparin-induced thrombocytopenia/ thrombosis (HITT) is recognized as the most frequent and fatal symptom complexes in patients receiving heparin therapy. The antibodies of HITT are not directly bound to heparin... -
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- Usefulness of anti-PF4/heparin antibody test for intensive care unit patients with thrombocytopenia
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Park SH, Jang S, Shim H, Park GB, Park CJ, Chi HS, Hong SB
- KMID: 2251969
- Korean J Hematol.
- 2012 Mar;47(1):39-43.
- doi: 10.5045/kjh.2012.47.1.39
BACKGROUND: It is critical to differentiate heparin-induced thrombocytopenia (HIT) from disseminated intravascular coagulation (DIC) in heparinized intensive care unit (ICU) patients with thrombocytopenia because the therapeutic approach differs based on... -
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- The Incidence, Causes, and Prognostic Significance of New-Onset Thrombocytopenia in Intensive Care Units: A Prospective Cohort Study in a Korean Hospital
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Lim SY, Jeon EJ, Kim HJ, Jeon K, Um SW, Koh WJ, Chung MP, Kim H, Kwon OJ, Suh GY
- KMID: 2157956
- J Korean Med Sci.
- 2012 Nov;27(11):1418-1423.
- doi: 10.3346/jkms.2012.27.11.1418
This study was designed to investigate the incidence, causes, and outcomes of new-onset thrombocytopenia (NOT) in Korean intensive care units (ICUs). A prospective cohort study was conducted in medical ICUs... -
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- Identification of the Marker-Genes for Dioxin(2,3,7,8-tetradibenzo-p-dioxin)-Induced Immune Dysfunction by Using the High-Density Oligonucleotide Microarray
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Kim JA, Lee EJ, Kim HL
- KMID: 2166168
- Genomics Inform.
- 2004 Jun;2(2):75-80.
In a variety of animal species, the perinatal exposure of experimental animals to the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) leads to the immune dysfunction, which is more severe and persistent than that caused... -
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- Utility of ELISA Optical Density Values and Clinical Scores for the Diagnosis of and Thrombosis Prediction in Heparin-induced Thrombocytopenia
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Kim SY, Kim HK, Han KS, Kim I, Yoon SS, Park S, Kim BK
- KMID: 1096652
- Korean J Lab Med.
- 2011 Jan;31(1):1-8.
- doi: 10.3343/kjlm.2011.31.1.1
BACKGROUND: Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction caused by antibodies to the heparin/platelet factor 4 (PF4) complex, resulting in thrombocytopenia and prothrombotic state. HIT diagnosis is challenging and... -
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