- Usefulness of platelet factor 4 as an evaluation of hemocompatibility of artificial materials
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Chae SL, Cho HI, Lee DH, Chun HS, Cha YJ, Park SS, Han DK, Kim YH
- KMID: 1688375
- Korean J Hematol.
- 1993 Nov;28(2):313-323.
No abstract available. -
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- Anti-Heparin-Platelet Factor 4 Antibody is a Risk Factor for Vascular Access Obstruction in Patients Undergoing Hemodialysis
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Lee EY, Hwang KY, Yang JO, Hong SY
- KMID: 1099796
- J Korean Med Sci.
- 2003 Feb;18(1):69-72.
- doi: 10.3346/jkms.2003.18.1.69
Since heparin is an anticoagulant commonly used in hemodialysis and the patients on hemodialysis are repeatedly exposed to heparin, heparin may be the cause of the development of heparin-dependent antibodies... -
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- The Management of Heparin-induced Thrombocytopenia with Thrombosis after Open Heart Surgery: A Case Report
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Kim JB, Choi SY, Park NH
- KMID: 2228202
- Korean J Crit Care Med.
- 2010 Sep;25(3):168-171.
- doi: 10.4266/kjccm.2010.25.3.168
Heparin-induced thrombocytopenia (HIT) is a prothrombotic, immune-mediated adverse reaction to heparin therapy. It is caused by antibodies binding to a complex of heparin and platelet factor 4, and this leads... -
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- Platelet Activation Markers (beta-thromboglobulin and platelet factor 4) and Clopidogrel Drug Response in Patients with Myocardiac Infarction
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Park Y, Kim J, Jung J, Kwon K, Koo S
- KMID: 1821781
- Lab Med Online.
- 2015 Jul;5(3):137-142.
- doi: 10.3343/lmo.2015.5.3.137
BACKGROUND: Dual antiplatelet therapy (aspirin and clopidogrel) is used to prevent adverse cardiac events in patients undergoing percutaneous coronary intervention (PCI). Some patients do not respond adequately to clopidogrel. Beta-thromboglobulin... -
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- Heparin-induced Thrombocytopenia Type II after Free Flap Operation
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Baek J, Park JH, Cha IH, Kim HJ
- KMID: 1960470
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2013 Nov;35(6):408-411.
After radical excision of a tumor in the maxillofacial area, functional and esthetic reconstruction is needed, including flap surgery. Among the many etiologies of flap failure, venous thrombosis is one... -
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- Characterization of Heparin:PF4 Isoantibody Interaction to Platelets in Heparin-Induced Thrombocytopenia/ Thrombosis
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Kim KY, Chang YJ, Suh JS, Kim JS
- KMID: 2146196
- Korean J Clin Pathol.
- 1997 Dec;17(6):944-955.
BACKGROUND: Heparin-induced thrombocytopenia/ thrombosis (HITT) is recognized as the most frequent and fatal symptom complexes in patients receiving heparin therapy. The antibodies of HITT are not directly bound to heparin... -
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- Usefulness of anti-PF4/heparin antibody test for intensive care unit patients with thrombocytopenia
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Park SH, Jang S, Shim H, Park GB, Park CJ, Chi HS, Hong SB
- KMID: 2251969
- Korean J Hematol.
- 2012 Mar;47(1):39-43.
- doi: 10.5045/kjh.2012.47.1.39
BACKGROUND: It is critical to differentiate heparin-induced thrombocytopenia (HIT) from disseminated intravascular coagulation (DIC) in heparinized intensive care unit (ICU) patients with thrombocytopenia because the therapeutic approach differs based on... -
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- The Incidence, Causes, and Prognostic Significance of New-Onset Thrombocytopenia in Intensive Care Units: A Prospective Cohort Study in a Korean Hospital
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Lim SY, Jeon EJ, Kim HJ, Jeon K, Um SW, Koh WJ, Chung MP, Kim H, Kwon OJ, Suh GY
- KMID: 2157956
- J Korean Med Sci.
- 2012 Nov;27(11):1418-1423.
- doi: 10.3346/jkms.2012.27.11.1418
This study was designed to investigate the incidence, causes, and outcomes of new-onset thrombocytopenia (NOT) in Korean intensive care units (ICUs). A prospective cohort study was conducted in medical ICUs... -
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- Identification of the Marker-Genes for Dioxin(2,3,7,8-tetradibenzo-p-dioxin)-Induced Immune Dysfunction by Using the High-Density Oligonucleotide Microarray
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Kim JA, Lee EJ, Kim HL
- KMID: 2166168
- Genomics Inform.
- 2004 Jun;2(2):75-80.
In a variety of animal species, the perinatal exposure of experimental animals to the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) leads to the immune dysfunction, which is more severe and persistent than that caused... -
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- Utility of ELISA Optical Density Values and Clinical Scores for the Diagnosis of and Thrombosis Prediction in Heparin-induced Thrombocytopenia
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Kim SY, Kim HK, Han KS, Kim I, Yoon SS, Park S, Kim BK
- KMID: 1096652
- Korean J Lab Med.
- 2011 Jan;31(1):1-8.
- doi: 10.3343/kjlm.2011.31.1.1
BACKGROUND: Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction caused by antibodies to the heparin/platelet factor 4 (PF4) complex, resulting in thrombocytopenia and prothrombotic state. HIT diagnosis is challenging and... -
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