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Recent Progress in the Medical Therapy of Pituitary Tumors

Langlois F, McCartney , Fleseriu M

Management of pituitary tumors is multidisciplinary, with medical therapy playing an increasingly important role. With the exception of prolactin-secreting tumors, surgery is still considered the first-line treatment for the majority...
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Comparisons between Macroadenomas and Microadenomas in Cushing's Disease: Characteristics of Hormone Secretion and Clinical Outcomes

Hwang YC, Chung JH, Min YK, Lee MS, Lee MK, Kim KW

It has been suggested that the patients with Cushing's disease secondary to pituitary macroadenomas (>10 mm) have higher basal adrenocorticotropic hormone (ACTH) levels, which are less suppressible on high-dose dexamethasone...
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A patient with Cushing disease lateralizing a pituitary adenoma by inferior petrosal sinus sampling using desmopressin: a case report

Lim JH, Kim SJ, Jung MK, Kim KE, Kwon AR, Chae HW, Kim DH, Kim HS

A 14-year-old girl was referred for evaluation of the etiology of Cushing syndrome. During the previous 2 years, she had experienced weight gain, secondary amenorrhea, growth retardation, and back pain....
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Clinical Guidelines for the Diagnosis and Treatment of Cushing's Disease in Korea

Hur KY, Kim JH, Kim BJ, Kim MS, Lee EJ, Kim SW

Cushing's disease (CD) is a rare disorder characterized by the overproduction of adrenocorticotropic hormone due to a pituitary adenoma that ultimately stimulates excessive cortisol secretion from the adrenal glands. Prior...
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Long-term follow-up on Cushing disease patient after transsphenoidal surgery

Jeong I, Oh M, Kim JH, Cho JH, Choi JH, Yoo HW

Cushing disease is caused by excessive adrenocorticotropic hormone (ACTH) production by the pituitary adenoma. Transsphenoidal surgery is its first-line treatment. The incidence of Cushing disease in children and adolescents is...
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Cushing's Disease in an Obese Patient Accompanied by Recurrent Urinary Tract Infection and Nephrolithiasis

Hyun S, Kim JW, Hong MK, Kim MY, Lee SE, Lee SH, Kim J, Ahn J

  • KMID: 2270962
  • Korean J Obes.
  • 2011 Dec;20(4):219-221.
Cushing's disease can cause obesity, diabetes and hypertension. Nephrolithiasis is prevalent in obese population. A variety of factors influence the formation of nephrolithiasis such as gender, diet, and urinary excretion...
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Limited Diagnostic Utility of Plasma Adrenocorticotropic Hormone for Differentiation between Adrenal Cushing Syndrome and Cushing Disease

Hong AR, Kim JH, Hong ES, Kim IK, Park KS, Ahn CH, Kim SW, Shin CS, Kim SY

BACKGROUND: Measurement of the plasma adrenocorticotropic hormone (ACTH) level has been recommended as the first diagnostic test for differentiating between ACTH-independent Cushing syndrome (CS) and ACTH-dependent CS. When plasma ACTH...
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Surgical Outcomes of Pituitary Apoplexy

Kim JK, Park BJ, Cho KT, Lee SK, Cho MK, Kim YJ

  • KMID: 1904918
  • J Korean Neurosurg Soc.
  • 2005 Dec;38(6):450-455.
OBJECTIVE: Pituitary apoplexy is a rare clinical syndrome caused by pituitary hemorrhage, hemorrhagic infarction, or ischemic infarction within a pituitary tumor or surrounding structure. We analyzed surgical outcomes of pituitary...
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A rare case of multiple pituitary adenomas in an adolescent Cushing disease presenting as a vertebral compression fracture

Song JY, Mun SJ, Sung SK, Hwang JY, Baik SK, Kim JY, Cheon CK, Kim SY, Kim YM

Cushing disease in children and adolescents, especially with multiple pituitary adenomas (MPAs), is very rare. We report 17-year-old boy with MPAs. He presented with a vertebral compression fracture, weight gain,...
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A Case of Bilateral Adrenal Myelolipomas with Congenital Adrenal Hyperplasia

Lee JH, Kim JY, Kwon JW, Lee JK, Jeon EJ, Jung ED

Adrenal myelolipoma (AML) is a rare, usually benign, and nonfunctioning tumor. About 7-15% of adrenal incidentalomas are AMLs, composed of normal hematopoietic elements and mature adipose tissue. AML is usually...
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Cushing Disease Diagnosed with Bilateral Simultaneous Inferior Petrosal Sinus Sampling

Kim S, Lee SH, Chong HH, Lee WK, Hong MH

  • KMID: 2294784
  • J Korean Acad Fam Med.
  • 2003 Aug;24(8):746-751.
The most common endogenous cause of Cushing's syndrome is Cushing's disease. The evaluation of patients with suspected Cushing's disease and syndrome requires an understanding of the proper use and limitations...
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The Eosinophil Count Tends to Be Negatively Associated with Levels of Serum Glucose in Patients with Adrenal Cushing Syndrome

Lee Y, Yi HS, Kim HR, Joung KH, Kang YE, Lee JH, Kim KS, Kim HJ, Ku BJ, Shong M

BACKGROUND: Cushing syndrome is characterized by glucose intolerance, cardiovascular disease, and an enhanced systemic inflammatory response caused by chronic exposure to excess cortisol. Eosinopenia is frequently observed in patients with...
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