- Anticonvulsant Effect of Flutamide in vitro Seizure Model
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Kim WJ, Lee SY, Lee BI
- KMID: 1480900
- J Korean Epilepsy Soc.
- 2008 Dec;12(2):92-95.
PURPOSE: Flutamide (4-nitro-3-t-trifluoromethyl-isobutyranilide) is an androgen-receptor antagonist with typical antiandrogenic effect, used to treat androgen-dependent disorders such as prostate cancer. However, some reports noted that flutamide has direct effects to... -
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- Anxiolytic Action of Taurine via Intranasal Administration in Mice
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Jung JH, Kim SJ
- KMID: 2456219
- Biomol Ther.
- 2019 Sep;27(5):450-456.
- doi: 10.4062/biomolther.2018.218
Taurine has a number of beneficial pharmacological actions in the brain such as anxiolytic and neuroprotective actions. We explored to test whether taurine could be transported to the central nervous... -
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- The expression of the immediate early genes, c-fos, krox-24 and the late response gene, BKNF induced by antiepileptic drugs
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Suh SC, Park YC, Kim SK
- KMID: 2066085
- J Korean Neurol Assoc.
- 1997 Jun;15(3):542-554.
The expression of the c-fos and krox-24 (immediate early genes: IEGs) and the BDNF (late response gene) were investigated by convulsants such as kainate (KA, 200 micrometer), N-methyl-D-aspartate (NMDA, 10... -
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- Effect of GABA on the contratility of small intestine isolated from rat
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Huh JY, Kwon OC, Ha JH, Lee KY, Kim WJ
- KMID: 2377364
- Yeungnam Univ J Med.
- 1991 Dec;8(2):95-105.
- doi: 10.12701/yujm.1991.8.2.95
This study was designed to investigate the effect of GABA and related substances on the spontaneous contraction of rat small intestine. The rats (Sprague-Dawley), weighing 200-250g, were sacrificed by cervical... -
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- Effects of iontophoretically applied naloxone, picrotoxin and strychnine on dorsal horn neuron activities treated with high frequency conditioning stimulation in cats
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Jeong Y, Baik EJ, Nam TS, Paik KS
- KMID: 1066884
- Yonsei Med J.
- 1995 Aug;36(4):336-347.
- doi: 10.3349/ymj.1995.36.4.336
Transcutaneous electrical nerve stimulation(TENS), acupuncture-needling, and electroacupuncture are useful non-ablative methods in medical practice for relief of pain. These procedures appear to work by causing an increased discharge in afferent... -
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- Spinal Antinociceptive Mechanism of Isoflurane and Enflurane via the GABAA Receptor in Rats
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Choi DK, Kim YK, Ham KD, Hwang JH
- KMID: 1759990
- Korean J Anesthesiol.
- 2003 May;44(5):701-708.
- doi: 10.4097/kjae.2003.44.5.701
Background: Several studies have suggested that the spinal cord may be an important site of anesthetic action and have established that general anesthetics potentiate the effects of GABA at the... -
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- NMDA Receptor-dependent Inhibition of Synaptic Transmission by Acute Ethanol Treatment in Rat Corticostriatal Slices
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Choi SJ, Kim KJ, Cho HS, Kim SY, Yim DS, Cho YJ, Hahn SJ, Sung KW
- KMID: 1587467
- Korean J Physiol Pharmacol.
- 2006 Dec;10(6):303-307.
The effects of ethanol on corticostriatal synaptic transmission were examined, using extracellular recording and analysis of population spike amplitudes in rat brain slices, to study how acute ethanol intoxication impairs... -
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- Effect of diazepam on the oxytocin induced contraction of the isolated rat uterus
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Park YK, Lee SH, Kwon OC, Ha JH, Lee KY, Kim WJ
- KMID: 2377592
- Yeungnam Univ J Med.
- 1992 Dec;9(2):359-381.
- doi: 10.12701/yujm.1992.9.2.359
This study was designed to investigate the effect of diazepam on the spontaneous contraction and oxytocin induced contraction of the isolated rat uterus. Female rat (Sprague-Dawley) pretreated with oophorectomy and... -
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- Influence of GABAergic Receptors on Catecholamine Secretion in the Isolated Rat Adrenal Glands
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Hong SP, Lim DY, Oh JH, Choi CH, Yoo HJ, Lee JJ, Heo JB, Jang Y, Kim JH, Kang JW
- KMID: 2093551
- Korean Circ J.
- 1995 Dec;25(6):1197-1207.
- doi: 10.4070/kcj.1995.25.6.1197
BACKGROUND: The influence of gamma-aminobutyric acid(GABA), which is well-known as a major inhibitory neurotransmitter in central nervous system, on secretion of catecholamines(CA) was investigated in the isolated perfused rat adrenal... -
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- Korean red ginseng excitation of paraventricular nucleus neurons via non-N-methyl-D-aspartate glutamate receptor activation in mice
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Shen Y, Bhattarai , Park SJ, Lee GS, Ryu PD, Han SK
- KMID: 2407616
- J Vet Sci.
- 2018 Mar;19(2):172-178.
- doi: 10.4142/jvs.2018.19.2.172
It has been reported that Korean red ginseng (KRG), a valuable and important traditional medicine, has varied effects on the central nervous system, suggesting its activities are complicated. The paraventricular... -
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- Glycine- and GABA-mimetic Actions of Shilajit on the Substantia Gelatinosa Neurons of the Trigeminal Subnucleus Caudalis in Mice
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Yin H, Yang EJ, Park SJ, Han SK
- KMID: 2071731
- Korean J Physiol Pharmacol.
- 2011 Oct;15(5):285-289.
- doi: 10.4196/kjpp.2011.15.5.285
Shilajit, a medicine herb commonly used in Ayurveda, has been reported to contain at least 85 minerals in ionic form that act on a variety of chemical, biological, and physical... -
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- Somatostatin Inhibits Gonadotropin Releasing Hormone Neuronal Activities in Juvenile Mice
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Park SA, Bhattarai , Han SK
- KMID: 2169171
- Endocrinol Metab.
- 2011 Sep;26(3):210-217.
- doi: 10.3803/EnM.2011.26.3.210
BACKGROUND: The gonadotropin releasing hormone (GnRH) neurons perform a pivotal function in the central regulation of fertility. Somatostatin (SST) is an important neuromodulatory peptide in the central nervous system and... -
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