- A Case of Myelocytic Leukemia with Philadelphia Chromosome
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Kim TK, Lee SY, Lee WG, Park CM
- KMID: 1668206
- J Korean Pediatr Soc.
- 1980 Nov;23(11):970-974.
A 14 years old female patient with chronic myelocytic leukemia was presented. Characteristic blood features of peripheral blood smear and bone marrow findings, clinical symptoms and signs, Philadelphia chromosome are... -
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- A Novel Four-Way Translocation t(5;9;22;18)(q31;q34;q11.2;q21) in a Patient with Chronic Myelogenous Leukemia
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Kim WS, Park G, Jang SJ, Moon DS, Kang SH
- KMID: 2312282
- Lab Med Online.
- 2015 Apr;5(2):101-105.
- doi: 10.3343/lmo.2015.5.2.101
Chronic myelogenous leukemia (CML) is characterized by the presence of the Philadelphia chromosome, which is generated by a reciprocal t(9;22)(q34;q11) translocation. Variant Philadelphia chromosomes, found in 5-10% of CML cases,... -
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- A case of chronic myeloid leukemia with features of essential thrombocythemia in peripheral blood and bone marrow
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Byun YJ, Park BB, Lee ES, Choi KS, Lee DS
- KMID: 2172809
- Blood Res.
- 2014 Jun;49(2):127-129.
- doi: 10.5045/br.2014.49.2.127
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by overproduction of myeloid white blood cells. Philadelphia chromosome is an essential finding for CML diagnosis. Generally, a clinical diagnosis of... -
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- Two Cases of Philadelphia Chromosome-negative Essential Thrombocythemia Manifested bcr-abl Gene Rearrangement
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Jung TK, Lee NY, Suh JS
- KMID: 2146100
- Korean J Clin Pathol.
- 2001 Oct;21(5):327-330.
Discrepant results have been reported in terms of detecting bcr-abl transcripts in patients with essential thrombocythemia that are Philadelphia (Ph) chromosome-negative. We present two cases of Ph chromosome-negative essential thrombocythemia... -
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- A Case of Bone Marrow Necrosis in B-Acute Lymphoblastic Leukemia with Philadelphia Chromosome at Presentation
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Jeong IH, An GD, Lim HH, Woo KS, Kim KH, Kim JM, Lee JH, Han JY
- KMID: 2421008
- Lab Med Online.
- 2018 Oct;8(4):171-176.
- doi: 10.3343/lmo.2018.8.4.171
Bone marrow necrosis (BMN) is a pathologic state which is derived from various disease entities. Most commonly, it is accompanied by hematologic malignancies such as acute leukemia. The patients with... -
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- Complete remission of philadelphia chromosome-positive acute myeloid leukemia with imatinib mesylate
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Jang SB, Bae SH, Jung HR, Yoon SY, Jun EJ, Kang GW, Ryoo HM
- KMID: 2259216
- Korean J Med.
- 2010 Jan;78(1):132-137.
Philadelphia chromosome-positive acute myeloid leukemia (Ph+AML) is a rare disease characterized by a poor prognosis with resistance to standard chemotherapy. We report a patient with Ph+AML with a minor BCR-ABL-positive... -
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- A t(3;3)(q21;q26) Acute Myeloid Leukemia with the Philadelphia Chromosome as a Secondary Change
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Han JY, Kim KH, Kim JS, Kim HJ, Nam R
- KMID: 1537194
- Korean J Hematol.
- 2000 Feb;35(1):67-71.
The Philadelphia chromosome (Ph) appears as a secondary change at the onset of disease. However, a late-appearing or secondary Ph has also been observed in rare cases of chronic myeloid... -
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- Philadelphia chromosome-positive acute lymphoblastic leukemia in childhood
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Koo HH
- KMID: 2284374
- Korean J Pediatr.
- 2011 Mar;54(3):106-110.
- doi: 10.3345/kjp.2011.54.3.106
In pediatric patients with acute lymphoblastic leukemia (ALL), the Philadelphia chromosome translocation is uncommon, with a frequency of less than 5%. However, it is classified as a high or very... -
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- Myelodysplasia-Related Features of Acute Myeloid Leukemia Evolving From Philadelphia-Negative Myeloproliferative Neoplasms
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Kim JR, Cho YU, Bae MH, Kim B, Jang S, Seo EJ, Chi HS, Park CJ
- KMID: 2373561
- Ann Lab Med.
- 2016 Jul;36(4):377-379.
- doi: 10.3343/alm.2016.36.4.377
No abstract available. -
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- Chronosomal Abnormalities in Patients with Hemato-Oncologic Disease: Analysis of 42 Cases
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Lee SN
- KMID: 1965136
- Ewha Med J.
- 1992 Dec;15(4):303-308.
- doi: 10.12771/emj.1992.15.4.303
With development of new technology such as handing technique and high resolution banding technique, cytogenetic examination has been utilized greatly in diagnosis and treatment of patients with hemato-oncologic diseases. Forty two... -
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- Complete Hematologic Response and Cytogenetic Remission after Imatinib and Dexamethasone Treatment of a Ph+ Precursor B-cell Acute Lymphoblastic Leukemia in Renal Transplantation Patient
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Baek SK, Cho KS, Yang BH, Kim SY, Yoon HJ, Jeong K, Ihm CG
- KMID: 2252177
- Korean J Hematol.
- 2009 Mar;44(1):62-66.
- doi: 10.5045/kjh.2009.44.1.62
In this report, we present a case of a patient with Philadelphia chromosome-positive (Ph+) B-cell acute lymphoblastic leukemia after renal transplantation. The patient, a 65-year-old man, had received a kidney... -
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- A case of basophilic crisis in a patient with chronic myelogenous leukemia
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Kim MS, Kim KW, Kim HJ, Park SY, Lee KS
- KMID: 2080816
- Korean J Med.
- 2001 Sep;61(3):293-297.
Chronic myelogenous leukemia (CML) is a clonal disorder of pluripotent hematopoietic stem cell. Transformation of CML can take place at different stages of stem cell development. The common terminal event... -
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- A Case of Eosinophilic Leukemia
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Lim CU, Yu HJ, Lee YS
- KMID: 1678292
- Korean J Dermatol.
- 1981 Aug;19(4):533-539.
Eosinophilic leukemia is a rare variant of granulocytic leukemia. It has distinct clinical features to involve central nervous system, heart, lung and skin more frequently than other leukemia and laboratory... -
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- Three cases of Philadelphia (Ph) chromosome positive acute myeloid leukemia (AML) treated with imatinib mesylate (Glivec, STI571) and allogeneic hematopoietic stem cell transplantation after induction chemotherapy
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Yoon JH, Kim HJ, Nam HS, Park YJ, Eom KS, Min WS, Kim CC
- KMID: 2256446
- Korean J Med.
- 2007 Mar;72(3):326-330.
The Ph-chromosome is the hallmark of chronic myelogenous leukemia (CML), but it has also been reported infrequently for de novo AML. This cytogenetic variant of AML is characterized by a... -
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- The Outcome of Philadelphia Chromosome-Positive Adult ALL: Characteristics and Prognosis
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Song HH, Lee JH, Jeon BM, Lee JH, Seo EJ, Park CJ, Chi HS, Lee JS, Kim WK, Lee KH
- KMID: 1804470
- Cancer Res Treat.
- 2002 Aug;34(4):289-295.
The Philadelphia (Ph) chromosome is a well- known chromosome abnormality in adults with B-lineage ALL, and is associated with a poor prognosis. This study compared the clinical manifestations and prognosis... -
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- A Case of Chronic Neutrophilic Leukemia with Multiple Myeloma
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Kim KH, Kim OY, Jo CH, Lee SO, Yoon BH, Kang MW, Lim YK, Yeu HS, Lee MH
- KMID: 1849152
- Korean J Hematol.
- 1998 Oct;33(3):454-459.
Chronic neutrophilic leukemia(CNL) is a rare disorder characterized by persistent neutrophilia of mature cell type without evidence of infection, hepatosplenomegaly, elevated neutrophil alkaline phosphatase score and the absence of Philadelphia... -
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- Outcome of Treatment in Children with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
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Chung NG, Lee SJ, Kim SY, Jang PS, Cho B, Jeong DC, Kim HK
- KMID: 2278293
- Korean J Pediatr Hematol Oncol.
- 2003 Oct;10(2):189-197.
PURPOSE: The prognosis of Philadelphia chromosome-positive acute lymphoblastic leukemiaacute lymphoblastic leukemia with Philadelphia chromosome (Ph ALL) is generally poor and reports from large studies are scarce. We evaluated the clinical... -
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- A case of chronic neutrophilic leukemia
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Hong SC, Kim JH, Lee JM, Chung JO, Kim YK, Kim SY, Lee GI
- KMID: 2081233
- Korean J Med.
- 2006 Sep;71(3):328-332.
Chronic neutrophilic leukemia (CNL) is a rare myeloproliferative disorder characterized by clonal proliferation of mature neutrophils, hepatosplenomegaly, elevated leukocyte alkaline phosphatase score (ALP score) and a negative Philadelphia chromosome. To... -
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- Complete Remission by Imatinib Mesylate (Glivec) in a Child Relapsing with Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph (+) ALL) after Unrelated Donor Stem Cell Transplantation
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Kim YY, Yoo YK, Kim SY, Jang PS, Chung NG, Cho B, Jeong DC, Lee SJ, Kim HK
- KMID: 2278285
- Korean J Pediatr Hematol Oncol.
- 2003 Apr;10(1):110-114.
The prognosis of patients with Philadelphia chromosome positive acute lymphoblastic leukemia (Ph ALL) who relapsed after allogeneic stem cell transplantation (allo-SCT) is poor. Imatinib mesylate (Glivec (R) ) is an... -
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- The incidence of ABL Deletion on Derivative 9 Chromosome in Chronic Myelogenous Leukemia by Interphase Fluorescence In Situ Hybridization and its Association with Progression to Blast Crisis
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Jeong S, Lee DS, See CJ, Ko EK, Park S, Cho HI
- KMID: 2225972
- Korean J Clin Pathol.
- 2000 Dec;20(6):521-526.
BACKGROUND: Philadelphia(Ph) chromosome is found in about 95 percent of chronic myelogenous leukemia(CML) patients. Ph chromosome results from a reciprocal translocation between the long arms of chromosomes 9 and 22,... -
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