- Gut Hormones and Appetite Control: A Focus on PYY and GLP-1 as Therapeutic Targets in Obesity
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De Silva A, Bloom SR
- KMID: 2167358
- Gut Liver.
- 2012 Jan;6(1):10-20.
The global obesity epidemic has resulted in significant morbidity and mortality. However, the medical treatment of obesity is limited. Gastric bypass is an effective surgical treatment but carries significant perioperative... -
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- Food Intake and Gut Hormones
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Cho YH, Lee SY
- KMID: 2271026
- Korean J Obes.
- 2013 Dec;22(4):197-204.
Peptide hormones, which regulate appetite, energy expenditure and glucose homeostasis, are released from the gastrointestinal tract in response to nutrients and they communicate information to the brain regarding the current... -
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- Loss of CD10/NEP Expression in the Pulmonary Carcinogenesis
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Myoug N
- KMID: 1972963
- Cancer Res Treat.
- 2002 Feb;34(1):17-22.
PURPOSES: The cell surface metalloproteinase CD10/ neutral endopeptidase 24.11 (NEP) hydrolyzes a variety of peptide substrates and reduces cellular responses to specific peptide hormones. CD10/NEP has been recognized as modulating... -
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- Obesity and Functional Gastrointestinal Disorders
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Lee KJ
- KMID: 1775826
- Korean J Gastroenterol.
- 2012 Jan;59(1):1-7.
- doi: 10.4166/kjg.2012.59.1.1
Obesity is prevalent in Korea. An increase in food intake and a decrease in energy expenditure are responsible for obesity. Gut hormones play a role in controlling food intake. Obesity... -
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- Detection of the Gonadotropin Releasing Hormone (GnRH) and Its Receptor in Cancer Cell HT-1197 and HT-1376, and Effect of GnRH on Cancer Cell Cycle
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Baik SH, Kim MO, Bahk JY
- KMID: 2292368
- Korean J Urol.
- 2001 Feb;42(2):172-179.
Gonadotropin releasing hormone (GnRH) is believed to be pivotal hormone in hypothalamo-pituitary gonadal axis and the hypothalamus is believed as the exclusive organ producing GnRH and pituitary is for GnRH... -
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- A Case of Multicentric Duodenal Carcinoid
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Lee HK, Je SJ, Kwon SJ, Lee DY, Suh KH, Lee SM, Lee CK
- KMID: 1929556
- Korean J Gastrointest Endosc.
- 1999 Feb;19(1):93-97.
Carcinoid tumors are the most common endocrine tumors of gastrointestinal tract. Argentaffin cells are the origin of carcinoids. These cells belong to the amino precursor uptake and decarboxylation (APUD) system.... -
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- Peptide YY, Cholecystokinin, Insulin and Ghrelin Response to Meal did not Change, but Mean Serum Levels of Insulin is Reduced in Children with Prader-Willi Syndrome
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Paik KH, Jin DK, Lee KH, Armstrong , Lee JE, Oh YJ, Kim S, Kwon EK, Choe YH
- KMID: 1778350
- J Korean Med Sci.
- 2007 Jun;22(3):436-441.
- doi: 10.3346/jkms.2007.22.3.436
Prader-Willi syndrome (PWS) is a contiguous gene syndrome characterized by uncontrollable eating or hyperphagia. Several studies have confirmed that plasma ghrelin levels are markedly elevated in PWS adults and children.... -
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- Detection of the Expression of GnRH and GnRH Receptor mRNAs and Effect of GnRH on Prostate Cancer Cell Proliferation
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Bahk JY, Hyun JS, Chang YW, Lee H, Choi BS, Lee KI, Baik HC, Hong JW, Oh JY
- KMID: 2290106
- Korean J Urol.
- 1997 Sep;38(9):963-972.
Prostatic cancer is the typical hormone dependant cancer and several kinds of hormones are used for the treatment of prostate cancer. Since Harris had proposed the hypothalamo-pituitary gonadal axis, the... -
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- An Expression Levels Analysis of the Bitter Taste Receptors in the Murine Exocrine Glands
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Ki SY, Cho YK, Chung KM, Kim KN
- KMID: 2437479
- Int J Oral Biol.
- 2018 Mar;43(1):5-11.
- doi: 10.11620/IJOB.2018.43.1.005
Recent findings indicate that Type 2 taste receptors (T2Rs) are expressed outside the gustatory system, including in the gastrointestinal tracts and the exocrine glands, such as the submandibular (SM), parotid... -
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- Effects of steroids, gonadotropins and epidermal growth factor on ovarian surface epithelial cell proliferation in vitro
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Lee YM, Ilekis JV, Ferrrer K, Scoccia B
- KMID: 2270051
- Korean J Obstet Gynecol.
- 2001 Feb;44(2):229-234.
OBJECTIVE: This study was designed to investigate the ovarian carcinogenesis process related to various steroids and peptide hormones. METHODS: We tested the proliferative effect of estradiol (E), dihydrotestosterone (DHT), progesterone (P),... -
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- Changes of Coregulators, MAP Kinase Activity and p27/kip1 with Estrogen or Antiestrogen Treatment in Breast Cancer Cell Line
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Park S, Heo MK, Lee MJ, Kim JH, Park BW
- KMID: 2241932
- J Breast Cancer.
- 2008 Jun;11(2):56-63.
- doi: 10.4048/jbc.2008.11.2.56
PURPOSE: Estrogen, various polypeptide hormones and growth factors are associated with the development and progression of breast cancer. Coregulatory proteins are also associated with estrogen receptor (ER) transcriptional activity and... -
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- Pathophysiological Role of Hormones and Cytokines in Cancer Cachexia
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Kim HJ, Kim HJ, Yun J, Kim KH, Kim SH, Lee SC, Bae SB, Kim CK, Lee NS, Lee KT, Park SK, Won JH, Park HS, Hong DS
- KMID: 1120148
- J Korean Med Sci.
- 2012 Feb;27(2):128-134.
- doi: 10.3346/jkms.2012.27.2.128
We investigated the role of fasting hormones and pro-inflammatory cytokines in cancer patients. Hormones (ghrelin, adiponectin, and leptin) and cytokines (TNF-alpha, IFN-gamma, and IL-6) were measured by ELISA or RIA... -
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- Ghrelin; Influences on Helicobacter pylori-associated Gastric Diseases
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Choi JY, Hahm KB
- KMID: 782744
- Korean J Gastroenterol.
- 2006 Aug;48(2):75-81.
Recently, gastric Helicobacter pylori (H. pylori) colonization has been shown to affect the expression of leptin and ghrelin, hormones that control appetite and satiety. Gastric leptin, produced by chief and... -
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- Serum Concentrations of Insulin, Ghrelin, Adiponectin, Leptin, Leptin Receptor and Lipocalin-2 in Children with Celiac Disease Who Do and Do Not Adhere to a Gluten-Free Diet
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Janas RM, Rybak A, Wierzbicka-Rucińska A, Socha P, Śnitko R, Szaflarska-Popławska A, Stolarczyk A, Oralewska , Cytra-Jarocka E, Iwańczak , Grzybowska-Chlebowczyk U, Cichy W, Czaja-Bulsa G, Socha J
- KMID: 2412048
- Gut Liver.
- 2016 Jul;10(4):587-594.
- doi: 10.5009/gnl15404
BACKGROUND/AIMS: The roles of the many bioactive peptides in the pathogenesis of celiac disease remain unclear. To evaluate the serum concentrations of insulin, ghrelin, adiponectin, leptin, leptin receptor, and lipocalin-2... -
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- Gastric Autoantigenic Proteins in Helicobacter Pylori Infection
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Park JS, Lee SJ, Kim TH, Yeom J, Park ES, Seo JH, Jun JS, Lim JY, Park CH, Woo HO, Youn HS, Ko GH, Kang HL, Baik SC, Lee WK, Cho MJ, Rhee KH
- KMID: 1798129
- Yonsei Med J.
- 2013 Nov;54(6):1342-1352.
- doi: 10.3349/ymj.2013.54.6.1342
PURPOSE: This study tried to identify novel gastric autoimmune antigens that might be involved in aggravating the atrophic gastritis among patients with Helicobacter pylori infection using two-dimensional immunoblotting analysis. MATERIALS AND... -
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- Marked Suppression of Ghrelin Concentration by Insulin in Prader-Willi Syndrome
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Paik KH, Lee MK, Jin DK, Kang HW, Lee KH, Kim AH, Kim C, Lee JE, Oh YJ, Kim S, Han SJ, Kwon EK, Choe YH
- KMID: 1713157
- J Korean Med Sci.
- 2007 Apr;22(2):177-182.
- doi: 10.3346/jkms.2007.22.2.177
The plasma ghrelin has been reported to be elevated in Prader-Willi syndrome (PWS) and modulated by insulin. It was hypothesized that insulin might have a more pronounced effect on reducing... -
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